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  1. 536841
    “…RESULTS: Our data indicated that vimentin, αSMA, S100A4 and PFN2 levels were increased, and CD31 levels were reduced in glomerular endothelial cells of DN patients and rats. Our cell experiments showed that high glucose induced EndMT by augmenting PFN2 expression in HUVECs. …”
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    ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy
  2. 536842
    “…CONCLUSIONS: Despite positive telemedicine experiences, more support to facilitate video visits for patients and clinicians is needed. …”
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    Clinician Perspectives on Telemedicine: Observational Cross-sectional Study
  3. 536843
    “…A “medium” Cohen’s effect size of 0.5 showed a sizable, positive clinical effect of ASyMS on patients’ symptom experiences. Remote monitoring systems will be vital for future services, particularly with blended models of care delivery arising from the covid-19 pandemic. …”
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    Real time remote symptom monitoring during chemotherapy for cancer: European multicentre randomised controlled trial (eSMART)
  4. 536844
    “…Haplo-insufficient mice were utilized in these experiments in order to prevent potential systemic complications from elevated levels of mechanical stimulation produced by the MSI model. …”
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    1: Iqgap1 Signaling Promotes Foreign Body Response To Biomedical Implants
  5. 536845
    “…To further define the role of LMO3 in insulin-stimulated glucose uptake, insulin signaling, adipocyte bioenergetics, as well as endocrine function, experiments were conducted in 3T3-L1 adipocytes and newly differentiated human primary mature adipocytes, engineered for transient gain or loss of LMO3 expression, respectively. …”
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    LMO3 reprograms visceral adipocyte metabolism during obesity
  6. 536846
    “…Interviews revealed that factors undermining uptake were insufficient promotion and awareness building, and the platform of the intervention, with social media being less appealing due to previous negative experiences concerning discussion of sexuality on social media. …”
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    Uptake of and Engagement With an Online Sexual Health Intervention (HOPE eIntervention) Among African American Young Adults: Mixed Methods Study
  7. 536847
    “…Methods: This study was aimed to investigate the differences and similarities between CRS induced by COVID-19 and CAR-T therapy, then provide valuable experiences for early identification and controlling CRS progression in COVID-19. …”
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    Clinical Characterization and Risk Factors Associated with Cytokine Release Syndrome Induced By COVID-19 and Chimeric Antigen Receptor T-Cell Therapy
  8. 536848
    “…We assessed the effect of on-site access to PrEP on HIV incidence in this natural experiment. METHODS: We did a nested interrupted time-series study using data from the ECHO trial. …”
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    Incorporating oral PrEP into standard prevention services for South African women: a nested interrupted time-series study
  9. 536849
    “…The quasi‐experimental studies showed a small but not statistically significant benefit for the program group on official reports (odds ratio, 0.54; 95% CI [0.24–1.22], k = 7). One quasi‐experiment reported a nonsignificant effect for a victim report outcome (odds ratio, 1.76; 95% CI [0.50–6.14], k = 1). …”
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    Court‐mandated interventions for individuals convicted of domestic violence: An updated Campbell systematic review
  10. 536850
    “…After that, the microengineered endometrium was cultured for an additional 5–6 days (total ∼ 14 days) for the purpose of each experiment. PARTICIPANTS/MATERIALS, SETTING, METHODS: Microfluidic 3D cultures were maintained in endothelial growth Medium 2 with or without oestradiol and progesterone. …”
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    Three-dimensional microengineered vascularised endometrium-on-a-chip
  11. 536851
    “…Within the causal impact evaluation, we nested a mixed-methods performance evaluation measuring mentor mothers’ time use and eliciting their subjective experiences through in-depth interviews. At both points of follow-up, we observed no statistically significant differences between the video intervention and the control arm with regard to EBF rates and other infant feeding practices [EBF in the last 24 hours at 1 month: RR 0.93 (95% CI 0.86 to 1.01, P = 0.091); EBF in the last 24 hours at 5 months: RR 0.90 (95% CI 0.77 to 1.04, P = 0.152)]. …”
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    Evaluation of a community-based mobile video breastfeeding intervention in Khayelitsha, South Africa: The Philani MOVIE cluster-randomized controlled trial
  12. 536852
    “…MATERIAL AND METHODS: In this paper, according to the institutional protocol approved by the institutional ethics and research committee FMUSP n° 964/2017 and protocol was in accordance with current international regulations for the use of animals in Research: Reporting In Vivo Experiments (ARRIVE) guide. Ten male pigs weighing 20 to 22kg were used. …”
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    Videolaparoscopic prostatectomy in porcine model for training residents
  13. 536853
    “…Despite the relatively high prevalence of CP, information about the experiences and function of adults with CP in our society continues to be limited. …”
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    Well-Being of Ambulatory Adults With Cerebral Palsy: Education, Employment, and Physical Function of a Cohort Who Received Specialized Pediatric Care
  14. 536854
    “…At the end of the 9th week, rats in CCl(4) + Lac and CCl(4) + CM groups had lactulose gavage at a dose of 10 mL/kg body weight, while normal control and CCl(4) groups had gavage with the same volume of normal saline once a day for 21 days until the end of the experiment. Rats in CCl(4) + EA and CCl(4) + CM groups underwent acupuncture at Baihui (GV[DU]20), Shenting (GV[DU]24), and Zusanli (ST36) acupoints, among which EA at Baihui and Shenting acupoints were given once daily for 30 min lasting for 21 consecutive days. …”
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    Electroacupuncture Synergistically Inhibits Proinflammatory Cytokine Production and Improves Cognitive Function in Rats with Cognitive Impairment due to Hepatic Encephalopathy through p38MAPK/STAT3 and TLR4/NF-κB Signaling Pathways
  15. 536855
    “…Here, we examined whether exosomes from sleep apnea patients can alter melanoma cell properties, and whether such effects were attributable to selected microRNA candidates, and affected melanoma cells harboring different mutations differently. In these experiments, the divergent responses of three melanoma cell lines to exosomes from sleep apnea patients before and after treatment indicated that STK11 gene mutations in melanoma cells make them particularly responsive to sleep apnea by altering cellular metabolism, and that specific microRNAs appear to underlie such effects. …”
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    Heterogeneity of Melanoma Cell Responses to Sleep Apnea-Derived Plasma Exosomes and to Intermittent Hypoxia
  16. 536856
    “…These results are useful in understanding how altitude and temperature influence secondary hair follicle development. ABSTRACT: This experiment compared secondary hair follicles (SFs) in Tibetan cashmere goats from two different steppes that were at different altitudes and had different temperatures. …”
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    Altered Hypoxia-Induced and Heat Shock Protein Immunostaining in Secondary Hair Follicles Associated with Changes in Altitude and Temperature in Tibetan Cashmere Goats
  17. 536857
    “…As for the amplification factor, there was RKY+ZOL+PHA group>ZOL+PHA group>RKY+PHA group>RKY+ZOL group>PHA group>ZOL group>RKY group>PBMC control group. In the killing experiment, the killing rate ([Formula: see text] , %) of group ① to group ⑧ was 1.08 ± 0.03, 1.89 ± 0.14, 1.22 ± 0.11, 1.31 ± 0.09, 1.48 ± 0.10, 2.02 ± 0.21, 2.18 ± 0.27, and 2.37 ± 0.35, whereas the comparison between groups was F = 20.498 and p < 0.001. …”
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    Study on the Killing Effect of γδT Cells Activated by Rukangyin on Breast Cancer MDA-MB-231 Cells
  18. 536858
    “…Monopustular Puccinia spp. isolates were used for virulence genetics analysis. In experiments to study the specialization of rust species from wild-growing cereals on common wheat, 12 winter cultivars were used (Grom, Tanya, Yuka, Tabor, Bezostaya 100, Yubileynaya 100, Vekha, Vassa, Alekseich, Stan, Gurt, Bagrat). …”
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    Wild grasses as the reservoirs of infection of rust species for winter soft wheat in the Northern Caucasus
  19. 536859
    “…We aimed to evaluate the Parsortix microfluidic device for CTC enrichment and characterisation in HNSCC, seeking to optimise a sample collection and processing protocol that preserves CTC integrity and phenotype. Method: Spiking experiments of the FaDu and SCC040 HNSCC cell lines were used to determine the Parsortix capture rate of rare “CTC-like” cells. …”
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    Immediate Sample Fixation Increases Circulating Tumour Cell (CTC) Capture and Preserves Phenotype in Head and Neck Squamous Cell Carcinoma: Towards a Standardised Approach to Microfluidic CTC Biomarker Discovery
  20. 536860
    “…These mycotoxins could adversely affect the health of broilers, and the most effective method to mitigate the toxic effects of mycotoxins is the use of detoxifying agents. In the present experiment, broiler chickens were allotted into five groups. …”
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    Effect of a Mycotoxin Binder (MMDA) on the Growth Performance, Blood and Carcass Characteristics of Broilers Fed Ochratoxin A and T-2 Mycotoxin Contaminated Diets
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