“…Three pairs of small interfering RNAs targeting YKL-40 (si-YKL-40-1/2/3) and the negative control (NC) were designed and used to transfect A549 cells, respectively, and the expression of YKL-40 was determined by RT-qPCR and Western blot. si-YKL-40-3 was screened out for subsequent experiments. In A549 cells, si-YKL-40-3 and si-NC were transfected and, then, IL-1β (20 ng/mL) was added in for culturing. …”
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“…On the other hand, increased expression of filaggrin, involucrin, and plakoglobin and decreased expression of vimentin were observed in constructs cultured in an air–liquid system. In vivo experiments demonstrated the potential of both hADM and hADM/hWJ-MSCs constructs to repair skin wounds with the formation of stratified epithelium, basement membrane and dermal papillae, improving the appearance of the repaired tissue. …”
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“…Tail vein-injected xenograft experiments were performed to study lung metastasis. …”
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“…The bone cement injectors were invented based on anatomical parameters of lumbar pedicle in Chinese elderly patients. Mechanical test experiments were performed on the bone cement injectors according to the three groups, namely, a local augmentation group, a full-length augmentation group, and a control group. …”
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“…Selected miRNAs were validated by qRT-PCR in 14 patients with T2DM on metformin monotherapy, without established CV disease and antiplatelet therapy during a stepwise hypoglycaemic clamp experiment and a follow-up 7 days after the clamp event. …”
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“…CONCLUSIONS: LC3 and Beclin-1 were more highly expressed in NOA testes and negatively correlated with the expression of miR-188-3p, suggesting that miR-188-3p may be involved in the process of autophagy in NOA. miR-188-3p may regulate its target gene ATG7 to participate in autophagy anDual luciferase experiment d affect the development of NOA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12958-022-00951-0.…”
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“…Interestingly, we identified a hPSC-BC population characterized by the expression of both CD144 and CD45. hPSC-ECs and hPSC-BCs were analyzed by flow cytometry and RT-qPCR; in vivo experiments have been realized by ischemic tissue injury model on a mouse dorsal skinfold chamber and hematopoietic reconstitution in irradiated immunosuppressed mouse from hPSC-ECs and hPSC-EB-CD144(+), respectively. …”
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“…IF assays were performed in both cancer cells and tumour xenograft paraffin sections to analyze the protein expression. The in vivo experiments in mouse model were performed to show the α5-nAChR-mediated immune escape via PD-L1 pathway. …”
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“…Compared with other preparations (Sal A solution, NLC-Sal A, DOX solution, DOX injection, Sal A/DOX solution, NLC-DOX, NLC-Sal A/DOX, and E-[c(RGDfK)(2)]/FA-NLC-Sal A/DOX) in this experiment, the prepared E-[c(RGDfK)(2)]/FA-NLC-Sal A/DOX had the best anti-tumor effect. …”
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“…Clinical observations, food intake, and rat weight were all recorded during the experiment. In addition, several biochemical parameters, organ weight, and histology of the liver and kidney were all evaluated. …”
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“…This is the normal condition in the Atlas experiment and need to be studied in great detail. The effect of the magnetic field on the shower development is to deflect the particles of the shower in the $\phi$ direction, and this effect can be very large for low energy electrons, that can be deflected up to 4 middle cell width. …”
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“…<br /> The reference to quantum mechanics will be proven to be profound: Brecht seizes on the problem of causality in quantum mechanics to counter the claim of objective necessities and strict determinism in social processes. The thought experiment of Heisenberg's microscope describes an unavoidable influence of the observer on its object. …”
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“…Here, we have investigated the lattice location and thermal stability of the implanted 3d TM probes $^{56}$Mn, $^{59}$Fe, $^{61}$Co and $^{65}$Ni in both lightly and heavily doped n- and p-type Si by means of emission channeling experiments. In all cases we identified ideal substitutional (S) sites, displaced bond-centered (near-BC) sites and displaced tetrahedral interstitial (near-T) sites. …”
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“…To evaluate potential nephrotoxic effects of such a therapy, an additional experiment was performed in mice without tumors. Therapeutic amounts of $^{177}$Lu-EC0800 were injected into the animals either with or without pre-injection of subtherapeutic amounts of PMX. …”
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“…Among the questions left open is the striking imbalance of matter and antimatter in our universe, which inspires experiments to compare the fundamental properties of matter/antimatter conjugates with high precision. …”
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“…&nbsp;À tour de rôle, a</span></span></span>rmés de balances, d’aimants ou encore d'une&nbsp;caméra infrarouge, ils ont réalisé diverses expériences. Certains ont&nbsp;même essayé de tricher avec un endoscope ! …”
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“…Now the real problem is to find the funds (about 1.3 billion US dollars) to make such a project become reality or, at least, reach the stage of a full-scale experiment The point is: who and why should take the risks of financing it? …”
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“…The acquired knowledge is sufficient to adopt this solution for the LHC accelerator at CERN, where about 5 km of this machine will be coated as well as the intersection vacuum chambers for the physics experiments. Meanwhile, coated chambers have already been successfully used on other accelerator, namely at ESRF (Grenoble, France) and Elettra (Trieste, Italy).…”
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“…Baianu KEYWORDS: FT-NIR and FT-IR Instruments, applications of FCS/NIR; Agricultural biotechnology; IR Chemical Imaging and NMR Microspectroscopy; DNA/RNA Micro-array analysis by NIR; High resolution and super-resolution FT-NIR/IR; IR Chemical Imaging by FPAW, Spotlight 300 Microspectrometer; Two photon NIR excitation for FCS; Single Cell and single molecule dynamics; FCS of molecules, single cells, Soybean oil, protein and moisture analysis; FT-NIR and FT-IR, high-resolution NMR of soybean oil in seeds and somatic embryos; chemical mutagenesis of soybean embryos; picomole FT-NIR and femtomole FCS-NIR analysis of single cells; phytochemicals detection in soybean seeds and cells by FT-NIR; high-power, femtosecond Ti:Sapphire NIR excitation for FCS, FCS/PCR; Nucleic acid hybridization, FT-IR and FT-NIR Images of Soybeans and Embryos; FT-IR and NIR Chemical Imaging Tests; Spatial Resolution Test in FT-NIR Micro-Imaging; FT-NIR Images of Soybeans and Embryos; FT-IR Reflectance Chemical Images; Somatic Embryos; NIR Reflectance Chemical Image of a Red Coat Azuki Red Bean; FT-NIR Chemical Imaging by Difference Spectroscopy (CIDS); High Resolution NMR Analysis of Soybean Oil in Somatic Embryos; HR NMR, H-1 NMR Spectrum of somatic soybean embryogenic cultures; TEM Micrograph of a Suspension of Soybean Somatic Embryos in Culture; Single Molecule Detection, two-photon excitation, one-photon excitation, three-photon-excitation, Fluorescence Correlation Spectroscopy (FCS); Fluorescence Resonance Energy Transfer (FRET); Fluorescence Lifetime Imaging Microscopy (FLIM); Fluorescence Recovery After Photobleaching (FRAP); Single Photon Confocal Fluorescence Correlation Spectroscopy; Inverted Epifluorescence Microscope; FCS auto-correlation, Fluorescence Fluctuations, Fluorescence Intensity, Fluorescence Correlation Spectroscopy and Imaging Experiments in Solutions and Plant Cell Suspensions; Pulsed, Two-Photon NIR Laser Excitation; Multi-photon (MPE) NIR excitation; FCS Alba Spectrometer Microspectrometer System; FCCS Cross-Correlation with Two Fluorescent Labels; FCCS Applications to DNA Hybridization.…”
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