“…CONCLUSIONS: This study shows how rational strain engineering combined with an efficient design of experiment approach systematically uncovered the promoting effect of uncoupling for optimising the formation of the early oxygenated taxane precursors of Taxol®. …”
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“…In this study, QuEChERS coupled with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was established for the simultaneous determination of 40 plant growth regulators, fungicides, insecticides, and antibiotics in bean sprouts. In the HPLC-MS/MS experiment, gibberellic acid, 4-fluorophenoxyacetic acid, chloramphenicol, N6-(δ2-isopentenyl)-adenine, 6-benzylaminopurine, 4-chlorophenoxyacetic acid, and 2,4-dichlorophenoxyacetic acid (2,4-D) were analyzed by MS/MS with negative electrospray ionization (ESI(-)). …”
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“…In the experimental study section, 40 pilots from each of the early morning (4:00), noon (12:00) and evening (20:00) departures operating under the exemption policy were selected to collect KSS scale data and PVT test data during their duty periods, and a total of 120 other pilots operating under the CCAR-121 policy were selected for the same experiment. First, the KSS scale data results found that flight pilots, whether flying under the exemption policy or under the CCAR-121 policy, had overall similar KSS scores, maintained KSS scores below the fatigue risk threshold (i.e., KSS score < 6) during the flights and that the empirical KSS data and the model simulation results from the KSS data were overall identical at the test nodes during the flight and had nearly identical trends. …”
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“…To further elucidate the experiences of women reporting unwanted sex, open-ended responses to an item querying “how the coronavirus pandemic is affecting your sex life” were assessed using conventional content analysis. …”
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“…Next, standard addition experiments were performed under three spiking levels, including 15, 50, and 200 μg/L. …”
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“…Some extraction parameters affecting the extraction efficiency, such as solution pH, adsorbent amount, adsorption time, desorption solvent and its volume, and desorption time were optimized using the single factor experiment method. Under the optimized extraction conditions (30 mg of adsorbent, 15 min of adsorption time, 40 μL of ammonia, 600 μL of acetonitrile-formic acid (9∶1, v/v) as desorption solvent, 1 min of desorption time), the performance, and applicability of the proposed method were investigated by combining magnetic solid-phase extraction, high performance liquid chromatography, and UV-visible detector. …”
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“…Combined with gas chromatography-tandem mass spectrometry (GC-MS/MS), a new method for the determination of PAHs in environmental water samples was established. Single factor experiments were performed to investigate the effects of the SPME conditions on the analytical performance. …”
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“…Specifically it is recommended that national bulk tank SCC data are made available for public good research. Past experiences with Schedule 8 prescribing (no longer permitted from 28 January 2022) may influence current efforts towards improved intramammary AM stewardship. …”
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“…RESULTS: A total of 306 patients were enrolled in the follow-up experiment finally: 153 in the intervention group and 153 in the control group. …”
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“…Cette enquête en ligne faisait partie d’un projet de recherche international sur la COVID-19 visant à fournir des informations sur les expériences vécues par les femmes enceintes et les mères ayant accouché dans les 3 derniers mois, pendant la troisième vague de la pandémie. …”
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“…LIMITATIONS: Subjective experiences, such as an individual's response to therapy, are intrinsically challenging to quantify as objective, factual realities. …”
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“…Piezo1 flox-mucin2 Cre mice showed decreased mucus expression and increased methylation compared to wild-type mice. Cell experiments showed that mechanical stimulation induced the activation of Piezo1, decreased H3K9me3 and SUV39h1, and upregulated mucin2 expression. …”
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“…CASE STUDY METHODS: To complement current discussions, we present an exploratory virtual experiment to determine how Digestible Indispensable Amino Acid Scores (DIAAS) might play a role in nLCA development by correcting for amino acid quality and digestibility. …”
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“…METHODS AND RESULTS: Rats in the experimental group were intraperitoneally injected with a single dose of 60 mg/kg monocrotaline (MCT group, n = 32) on the first day of the experiment, whereas rats in the control group were injected with vehicle (CTL group, n = 32). …”
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“…CONCLUSIONS: The psychometric properties of the GHD-CTB–Child, GHD-CTB–Observer, and GHD-PTB support the validity of their use as PRO and ObsRO measures to capture the experiences associated with treatment burden for children with GHD and their parents/guardians in both clinical and research settings. …”
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“…We compared gene expression between three varying doses in the host and pathogen by contrasting experiment groups against the naïve control. RESULTS: A total of 4954 differentially expressed genes (DEGs) were detected after ASFV Ken12/1 infection, including 3055, 1771, and 128 DEGs in the high, medium, and low doses, respectively. …”
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“…The LHCb experiment is dedicated to precision measurements of CP violation and rare decays of B hadrons at the Large Hadron Collider (LHC) at CERN (Geneva) [1, 2]. …”
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“…This study allows to establish a broadband impedance model which can be use to predict the dynamics of the instability. A few experiments were done also with the use a gamma transition jump. …”
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“…Nowadays, an upgrade of the LHC to achieve instantaneous luminosities a factor of five larger than the LHC nominal value, thereby enabling the experiments to enlarge their data sample by one order of magnitude compared with the LHC baseline programme, has been developed, called the High Luminosity LHC (HL-LHC). …”
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“…DESIGN, SETTING, AND PARTICIPANTS: This cohort study used data from the Study of Healthy Aging in African Americans (STAR) and Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) study, which were harmonized longitudinal cohorts of racially and ethnically diverse adults aged 50 years and older from the San Francisco Bay area and Sacramento Valley in California. …”
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