“…In conclusion, efflux pumps may play an important role in INH acquired resistance in MDR M. tuberculosis, especially in those strains having no mutations in genes associated with INH resistance; basal expression levels of some efflux pump genes are higher in MDR isolates than in pan-sensitive isolates and the basal expressional differences may be helpful to diagnose and treat resistant tuberculosis.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…For the normalization of RT-qPCR with two dyes, SYBR Green and EvaGreen, the expressional stability of seven candidate reference genes in 43 O. fragrans samples was analyzed using geNorm, NormFinder and BestKeeper. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As deficiency in its corresponding receptor signaling complex ERBB2/ERBB3 leads to postnatal colonic hypo/aganglionosis we assessed the distributional and expressional pattern of the NRG1-ERBB2/ERBB3 system in the human colon and explored the neurotrophic capacity of NRG1 on cultured enteric neurons. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both transcriptional induction and potential feedback repression mediate the expressional regulation of the genes involved in Fe uptake and translocation in response to Fe deficiency. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The correlation between miR-26a or PLAG1 expressional abnormality and occurrence of pituitary adenoma is still unknown, as is its association with invasiveness of pituitary adenoma. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among parasitic factors altering host gene expression, CpBV-H4 alone explained 16.3% of these expressional changes. To characterize the joining sites of CpBV-H4 on host chromosomes, ChIP-Seq (chromatin immunoprecipitation followed by deep sequencing) was applied to chromatins extracted from parasitized larvae. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These results suggest that the methylation of the EPHB4 gene is prevalent in childhood ALL and may result in expressional inactivation, which consequently promotes ALL pathogenesis and is associated with an unfavorable prognosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Since these gene products are known to play a role in maturation and motility of sperm, a defect of at least MM-1α transcriptional activity is thought to induce expressional changes of these genes, resulting in male infertility.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, the OA model rats received miR-9 agomir for further expressional assay. Cartilage tissue samples from the OA patients exhibited significantly lower miR-9 and Col2A1 expression levels when compared with the control rats, whilst the expression level of MMP-13 was upregulated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The patients were followed up from 5 months to 13.5 years for survival analysis. The expressional levels of pAkt and Beclin 1 in invasive ductal breast cancer tissues, and the normal paracancerous tissues were measured by immunohistochemistry. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In ejaculated somatic cells of CP/CPPS patients we found that ESR1 and ESR2 were both significantly higher methylated in CpG-promoters and expressionally down-regulated in comparison to controls. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, fifteen miRNAs along with housekeeping gene were randomly selected and subjected to RT-PCR expressional validation. A total of 32927 targets are also predicted and annotated for these newly profiled wheat miRNAs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Studies involving clock-gene expressional patterns in fish peripheral tissues have attracted considerable attention. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results imply that epigenetic rather than genetic alterations are associated with the development of the distinct expressional and functional features, which define this MF phenotype in the tumor microenvironment.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CA9 suppression by inhibitors (S4 and U104) decreased viability and migration of MM cells, accompanied by overexpression of TFRC, IREB1/2 and FPN1(SLC40A1) and by downregulation of FTH/FTL. This expressional pattern was similar to that of erastin-induced ferroptosis in the same cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cis-element prediction and co-expression assay were used to confirm the expressional correlation between genes that are responsible for SGA biosynthesis and disease resistance. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This higher levels of SA in cucumber roots was consistent with the higher expressional levels of SA pathway genes PR1 and PR3. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To explore the potential functions and clinical significances of peroxisomes during lung cancer development and progression, we investigated the expressional profiles of peroxisome pathway genes and their correlations with clinical features in non-small cell lung cancer (NSCLC). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our results revealed the expressional changes associated with heat tolerance and identified potential key genes in the regulation of this process. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Levels of cytokines, anti-CII antibodies, and the proliferation and lineages of T cells from the draining lymph nodes were measured using ELISA and flow cytometry, respectively. The expressional changes, including STAT1, STAT3, Nrf2, KEAP-1, and heme oxygenase-1 (HO-1) changes in the paw tissues, were evaluated by Western blot assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso