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2281“…We hypothesized that early adversity impairs the use of learning signals -negative, aversive prediction errors–to reduce fear in uncertainty. To test this hypothesis, we gave adolescent rats a battery of adverse experiences then assessed adult performance in probabilistic Pavlovian fear conditioning and fear extinction. …”
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2282por Sivamaruthi, Bhagavathi S., Madhumita, Rajkumar, Balamurugan, Krishnaswamy, Rajan, Koilmani E.“…All the individuals were subjected to passive avoidance test on PND-30 to test their fear memory. We show that single dose of C. sakazakii infection improved fear memory retention. …”
Publicado 2015
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2283por Wei, Pengfei, Liu, Nan, Zhang, Zhijian, Liu, Xuemei, Tang, Yongqiang, He, Xiaobin, Wu, Bifeng, Zhou, Zheng, Liu, Yaohan, Li, Juan, Zhang, Yi, Zhou, Xuanyi, Xu, Lin, Chen, Lin, Bi, Guoqiang, Hu, Xintian, Xu, Fuqiang, Wang, LipingEnlace del recurso
Publicado 2015
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2284por Sakane, Naoki, Kotani, Kazuhiko, Tsuzaki, Kokoro, Nishi, Masami, Takahashi, Kaoru, Murata, Takashi, Yamada, Kazunori, Okazaki, Kentaro, Yanagisawa, Katsuyuki, Yamada, Kenichi, Kuribayashi, Nobuichi, Totsuka, Yasuo, Hiyoshi, Toru, Naka, Motoji, Sugimoto, Masatake, Aoki, Yuji, Waki, Masako, Furuya, Miyuki, Kitaoka, Haruko, Oishi, Mariko, Shimizu, Ikki, Miyaoka, Hiroaki, Okada, Akira, Yamamoto, Toshikazu“…The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. …”
Publicado 2015
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2285por Carson, L.D., Henderson, J. Neil, King, Kama, Kleszynski, Keith, Thompson, David M., Mayer, Patricia“…Specific findings included significant fear and anxiety surrounding 1) the health and well-being of the unborn child, 2) the use of insulin injections, 3) blindness, 4) amputation, and 5) death. …”
Publicado 2015
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2286por Steenen, Serge A., van Wijk, Arjen J., van Westrhenen, Roos, de Lange, Jan, de Jongh, Ad“…Moreover, evidence suggests that propranolol is capable of inhibiting “memory reconsolidation” (that is, it blocks the process of storing a recently retrieved fear memory). Hence, the purpose of this trial is to determine the anxiolytic and fear memory reconsolidation inhibiting effects of the ß-adrenoreceptor antagonist propranolol on patients with high levels of fear in anticipation of a dental extraction. …”
Publicado 2015
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2287por Xiong, Hui, Cassé, Frédéric, Zhou, Yang, Zhou, Ming, Xiong, Zhi-Qi, Joëls, Marian, Martin, Stéphane, Krugers, Harm J.“…Blocking the mTOR pathway also prevented the memory enhancing effects of corticosterone in a contextual fear-conditioning paradigm. We conclude that activation of the mTOR pathway is essential for the effects of corticosterone on synaptic trapping of AMPARs and, possibly as a consequence, fearful memory formation.…”
Publicado 2015
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2288“…These experiments examined the relationship between the neurotrophic factor fibroblast growth factor 2 (FGF2) and individual differences in the expression of conditioned fear. Experiments 1 and 2 demonstrated that rats naturally expressing low levels of contextual or cued fear have higher levels of hippocampal FGF2 relative to rats that express high levels of conditioned fear and nonconditioned rats. …”
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2289“…Virtual reality (VR) is a capable means of activating phobic fear in patients. The representation of the patient’s body (e.g., the right hand) in VR enhances immersion and increases presence, but its effect on phobic fear is still unknown. …”
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2291“…We tried to investigate the functional connectome alterations in PDO to re-examine the precision and role of fear network model for the pathophysiology of PDO. …”
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2292por Pattwell, Siobhan S., Liston, Conor, Jing, Deqiang, Ninan, Ipe, Yang, Rui R., Witztum, Jonathan, Murdock, Mitchell H., Dincheva, Iva, Bath, Kevin G., Casey, B. J., Deisseroth, Karl, Lee, Francis S.“…Fear can be highly adaptive in promoting survival, yet it can also be detrimental when it persists long after a threat has passed. …”
Publicado 2016
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2293por Hölzel, Britta K., Brunsch, Vincent, Gard, Tim, Greve, Douglas N., Koch, Kathrin, Sorg, Christian, Lazar, Sara W., Milad, Mohammed R.“…Mindfulness has been suggested to impact emotional learning, but research on these processes is scarce. The classical fear conditioning/extinction/extinction retention paradigm is a well-known method for assessing emotional learning. …”
Publicado 2016
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2294“…After activation of D4R or weak fear conditioning, STDP stimulation induces LTD in the LA-ITC synapses. …”
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2295“…Freezing, a characteristic pattern of defensive behavior elicited by fear, is associated with a decrease in the heart rate. …”
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2296“…Here we expose inbred C57BL/6J mice to a fear-inducing odorant (2,4,5-trimethylthiazole; mT) to model predation-induced weight regulation. …”
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2297por Dunkley, Benjamin T, Pang, Elizabeth W, Sedge, Paul A, Jetly, Rakesh, Doesburg, Sam M, Taylor, Margot JEnlace del recurso
Publicado 2016
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2298“…Fear of pain (FOP) can increase risk for chronic pain and disability but little is known about corresponding neural responses in anticipation of potential pain. …”
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2299Reducing the Meta-Emotional Problem Decreases Physiological Fear Response during Exposure in Phobicspor Couyoumdjian, Alessandro, Ottaviani, Cristina, Petrocchi, Nicola, Trincas, Roberta, Tenore, Katia, Buonanno, Carlo, Mancini, Francesco“…Preliminary findings support the role of the meta-emotional problem in the maintenance of response to the fearful stimulus (primary problem).…”
Publicado 2016
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2300por Pishnamazi, Morteza, Tafakhori, Abbas, Loloee, Sogol, Modabbernia, Amirhossein, Aghamollaii, Vajiheh, Bahrami, Bahador, Winston, Joel S.“…Despite this impairment in fear recognition, very brief (100 msec) fearful cues could orient SF's spatial attention. …”
Publicado 2016
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