“…Post-traumatic stress disorder (PTSD) is associated with impaired conditioned fear extinction learning, a ventromedial prefrontal cortex (vmPFC)-dependent process. …”
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“…Genetic variation in serotonin transporter (SERT) that reduces transcriptional efficiency is associated with higher anxiety and fear traits and a greater incidence of post traumatic stress disorder (PTSD). …”
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“…Social anxiety is characterized by a fear of being negatively evaluated by others (i.e., Fear of Negative Evaluation [FNE]). …”
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“…The ability to extinguish fear memory associations is impaired in PTSD individuals. …”
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“…Finally, in conjoint analyses with data from a previous sibling study (happy and fearful faces) we examined whether excitatory vmPFC-tDCS would reveal a general increase in processing of pleasant stimuli independent of the type of unpleasant stimuli applied (sad vs. fearful faces). …”
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“…In the present study, we examined a structural equation model whereby depression, social anxiety and lower life satisfaction predicted PFU severity, while analyzing mediating variables including rumination, fear of missing out (FoMO), and frequency of Facebook use, as well as age and gender as covariates. …”
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“…Besides, the relationship between error learning orientation and positive grieving is more positive for employees with lower levels of fear of face loss. Our findings help enrich the antecedents of learning from failure by shedding light on how and when error learning orientation matters. …”
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“…CONCLUSIONS: The effect of TMRK electro-acupuncture method on the regression of fear memory of PTSD rats may be through its repair of synaptic plasticity in amygdala and hippocampus.…”
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“…Although the biochemical signaling events in area CA1 of the hippocampus underlying memory acquisition, consolidation, retrieval, and extinction have been extensively studied, little is known about the activity dynamics of hippocampal neurons in CA1 during Pavlovian fear conditioning. Here, we use fiber-optic confocal microscopy coupled with the calcium indicator GCaMP6m to monitor neuron activity in freely moving mice during trace fear conditioning. …”
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“…Both the presence (or absence) of a mother hen and genetics may affect cognition, social interactions and fear. In this study, we showed that in our tests, genetics have a strong effect on fear and sociality. …”
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“…Together, these findings illustrate a unique epigenetic role of OGT via regulation of histone methylation mediated by EZH2 during memory consolidation of fear conditioned memories.…”
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“…This study aimed to analyze the details of “moving from fear to realization,” which is one category of a substantive theory of family engagement in tuberculosis prevention in children. …”
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“…BACKGROUND: Patients with head and neck cancer (HNC) are vulnerable to fear of cancer recurrence (FCR) and psychiatric morbidity. …”
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“…Furthermore, SD affected fear extinction through vHPC-IL proBDNF signaling, which was associated with NR2B subunits of NMDA receptors. …”
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“…We hypothesize that older adults with LBP are susceptible to disability based on the combination of two factors: fear of movement and dynamic inflammatory response to movement (DIR). …”
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“…BACKGROUND: Neuropeptide Y (NPY) has anxiolytic effects and facilitates extinction of cued and contextual fear in rodents, thereby acting as a resilience factor against exaggerated fear responses after adverse events. …”
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“…Cognitive function and memory were examined in young mice using the novel object recognition, contextual fear conditioning, and cued-fear extinction tests. …”
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“…Minimum clinically important differences (MCIDs), pre-post effect sizes, and 95% confidence intervals were examined for fear of movement using the Fear of Daily Activities Questionnaire (FDAQ) and Pain Outcomes Questionnaire-VA (POQ-VA; fear scale). …”
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