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  1. 293661
    “…For example, azathioprine (with or without biologics) is associated with hepatosplenic T cell lymphoma (and other forms of lymphoma) in adolescent and young adult males more often than females. Methotrexate is associated with birth defects in the growing fetus and therefore should be avoided in adolescent and adult women of child-bearing age who are not using two or more forms of birth control. 12. …”
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  2. 293662
  3. 293663
    “…Higher risk of incident IBD was associated with baseline antibiotic use [aOR: 2.81 (95% CI: 1.67-4.73), p=0.0001] and hormonal medication use [aOR: 4.43 (95% CI: 1.78-11.01), p=0.001]. Among females, previous or current oral contraceptive use was also associated with IBD development [aOR: 2.17 (95% CI: 1.70-2.77), p=5.02E-10]. …”
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  4. 293664
    “…Clearly, the thymectomized MMC mice were susceptible to arthritis (five out of 18 developed arthritis; Fig. 2), and no significant differences in susceptibility between thymectomized and sham-operated mice, or between males and females, were seen. In accordance with earlier results [14], MMC transgenic mice had a significantly reduced susceptibility to arthritis as compared with the nontransgenic littermates (P < 0.0001 for arthritic scores, disease onset and incidence). …”
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  5. 293665
    “…Appendicitis is the most common surgical emergencies worldwide, with a lifetime risk of 6.9% in females and 8.6% in males (Körner 1997). For over 100 years, open appendectomy had been the established treatment for appendicitis, but current management has evolved with the advent of laparoscopy and now growing use of antibiotics for treatment of appendicitis. …”
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  6. 293666
    por Barbui, Tiziano, Iurlo, Alessandra, Masciulli, Arianna, Carobbio, Alessandra, Ghirardi, Arianna, Carioli, Greta, Sobas, Marta, Elli, Elena Maria, Rumi, Elisa, De Stefano, Valerio, Lunghi, Francesca, Marchetti, Monia, Daffini, Rosa, Gasior Kabat, Mercedes, Cuevas, Beatriz, Fox, Laura Maria, Andrade, Marcio, Palandri, Francesca, Guglielmelli, Paola, Benevolo, Giulia, Harrison, Claire N., Foncillas, Maria Angeles, Bonifacio, Massimiliano, Alvarez-Larran, Alberto, Kiladjian, Jean-Jacques, Bolaños, Estefanía, Patriarca, Andrea, Quiroz, Keina, Griesshammer, Martin, Garcia Gutierrez, Valentín, Marin Sanchez, Alberto, Magro, Elena, Ruggeri, Marco, Hernandez Boluda, Juan Carlos, Osorio, Santiago, Carreño Gomez-Tarragona, Gonzalo, Sagüés, Miguel, Kusec, Rajko, Navas, Begoña, Angona, Anna, Xicoy, Blanca, Lopez Abadia, Emma, Koschmieder, Steffen, Cattaneo, Daniele, Bucelli, Cristina, Cichocka, Edyta, Masternak, Anna, Cavalca, Fabrizio, Borsani, Oscar, Betti, Silvia, Bellini, Marta, Curto-Garcia, Natalia, Rambaldi, Alessandro, Vannucchi, Alessandro
    Publicado 2021
    “….: • Patients in the second wave were significantly different from those in the first wave, including parameters such as age (median: 63 vs. 71 years, p<.001), sex (females: 52% vs. 42%, p=0.037), MPN category (MF 24% vs. 34%, p=0.020), comorbidity (at least one comorbidity 63% vs. 74%, p=0.012), disposition (home: 68% vs. 23%, regular ward: 29% vs. 66%, ICU: 3% vs. 11%, p<.001), need of respiratory support (28% vs. 59%, p<.001) and degree of systemic inflammation (C-Reactive Protein: 51% vs. 74%, p=0.008; Neutrophil to Lymphocyte Ratio: 4.1 vs. 5.4, p=0.038). • In regard to COVID-19-directed therapy, in the second wave steroids were more frequently prescribed (28% vs. 40%, p=0.007), while the use of antibiotics, antivirals, hydroxychloroquine and experimental therapies was significantly less frequent (p<.001 for all the differences). …”
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  7. 293667
    “…The gender distribution of the sample has shown that males were more than females. Table 3 shows the psychiatric diagnosis made by the psychiatrist of the total sample. 64 (29.9%) of the patients had SMD (Severe Mental Disorders), 73 (32.8%) had CMD (Common Mental Disorders), and 36 (14.7%) had substance use disorders. …”
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