“…The phenotypic spectrum in affected 46XY males may vary from surgically repairable defects including cryptorchidism and hypospadias to complete feminization of external gonads, accompanied by symptoms of adrenal dysfunction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Decision-makers should consider that benefits of P4P be monitored not only for patient metrics but also for provider metrics in terms of gender equality especially given feminization of primary care medical workforces.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, data show an improvement in the quality of life for transgender people who use feminizing hormone therapy. With few transgender-specific data, guidance may be drawn from cisgender (nontransgender) data, with a focus on hormonal birth control and postmenopausal hormone replacement therapy (HRT). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nix, a gene in the M-locus, was shown to be a male-determining factor (M factor) as somatic knockout of Nix led to feminized males (M/m) while transient expression of Nix resulted in partially masculinized females (m/m), with male reproductive organs but retained female antennae. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The clinical significance of erythrocytosis following testosterone therapy, as well as anemia following feminizing HT, requires further investigation.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The research revealed that under the influence of macroeconomic conditions, the change in the sociocultural context in 2006–2019 contributed to expansion of the geography of migration flows from Uzbekistan, the emergence of such phenomena as the “feminization” of migration and its “rejuvenation” against the background of certain elements of egalitarianism in an initially patriarchal society. …”
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Feminization-1 (FEM-1) is considered a substrate recognition subunit of CUL2-RING E3 ubiquitin ligase complexes, which refers to sex determination by modulating TRA-1 stability in C. elegans. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is often used in combination with estrogens in trans women to achieve feminization. However, CPA has been associated with side effects such as changes in liver enzyme concentrations and increases in prolactin concentrations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The effects of RNAi-mediated gene knockdown of MroDmrt11E on the differentially expressed and sex-related candidate genes, such as transformer, fruitless, feminization, insulin-like androgenic gland gene, Dmrt gene family, were primarily focused on, and their possible molecular regulatory relationships in sexual differentiation were analyzed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Overall, videos on masculinizing GAS had higher quality and reliability than videos on feminizing GAS (P < 0.001). Chest surgery videos were of higher quality than those on genital surgery (P ≤ 0.001). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The individuals carrying this genotype expressed only female-specific transcripts of feminizer and double-sex genes. By comparing the sequences differences between the csd pair identified in our study with those described earlier, we conclude that functional heterozygosity of the csd gene is dependent not only on the number of the amino acid differences but also on the sequence context and position of the change. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Transgender individuals with Klinefelter syndrome need to manage a unique risk profile if they desire feminizing gender‐affirming hormone therapy.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Importantly, co-immunofluorescence demonstrated that Raptor deficiency induced SCs dedifferentiation into a progenitor state; the Raptor-mutant gonads showed some ovarian somatic cell features, accompanied by enhanced female steroidogenesis and elevated estrogen levels, yet the zona pellucida 3 (ZP3)-positive terminally feminized oocytes were not observed. In vitro experiments with primary SCs suggested that Raptor is likely involved in the fibroblast growth factor 9 (FGF9)-induced formation of cell junctions among SCs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: This research indicates that nursing as a career choice for men is still underpinned by a lack of understanding of the actual role of the nurse and what nurses do, and is more supported by a societal perception that nursing is still a feminized profession. Findings can be used to make recommendations for change in the profession to strengthen diversity in the workforce and redefine the recruitment of men into nursing. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In a reciprocal experiment, feminization of the oenocytes and nervous system in males by expression of transformer (traF) elicited high levels of courtship and little or no aggression from control males. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Wolbachia can induce several reproductive phenotypes in their insect hosts including feminization, male-killing, parthenogenesis and cytoplasmic incompatibility (CI). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In arthropods, they manipulate the reproduction of their hosts to facilitate their own spread in host populations, causing cytoplasmic incompatibility, parthenogenesis induction, feminization of genetic males and male-killing. In this study, we investigated Wolbachia infection and studied wsp (Wolbachia surface protein) sequences in three wasp species associated with the unisexual galls of A. mukaigawae with the aim of determining the transmission mode and the reason for multiple infections of Wolbachia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In other cases, signs of feminization, hyperpigmentation or alopecia may be observed, most commonly associated with Sertoli cell tumours (SCT). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also identified sex differences in the transcript levels and activity of hepatic and adipose glucocorticoid metabolizing enzymes. Estrogen treatment feminized the pattern of DIO-induced changes in glucocorticoid metabolism, rendering males similar to females. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Altogether, the results show that EE2 has a great effect on gene expression in juvenile rainbow trout. The feminization process seems to result from the altered transcription of genes implicated in normal female gonad differentiation, resulting in expression similar to that observed in normal females (i.e. the repression of key testicular markers cyp17a1, cyp11b, tbx1), as well as from other genes (including transcription factors) that respond specifically to the EE2 treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso