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  1. 2501
    “…Nearly 80% of patients and caregivers agreed that advance care planning should be conducted when the patient was at a non-frail stage of disease. Patients’ frail stage of disease was considered the indicator for life-sustaining treatments withdrawal except for nutrition and fluid supplements, antibiotics or blood transfusions. …”
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    Preferences on the Timing of Initiating Advance Care Planning and Withdrawing Life-Sustaining Treatment between Terminally-Ill Cancer Patients and Their Main Family Caregivers: A Prospective Study
  2. 2502
    “…INTRODUCTION: Frail older adults are at an increased risk for adverse outcomes after an Emergency Department (ED) visit. …”
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    Frailty screening of Tunisian older adults: feasibility and usefulness in the Emergency Department
  3. 2503
    por Woods, Diana, Yefimova, Maria
    Publicado 2020
    “…Innovative technology may alert health providers to early signs of decline in frail older adults with multiple chronic conditions. …”
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    Using Big Data for Clinical Decision Making
  4. 2504
    “…DISCUSSION: Older adults who engaged in cultural activities every few months or more had a reduced risk of becoming frail and a slower progression of frailty over time. …”
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    Cultural Engagement Is a Risk-Reducing Factor for Frailty Incidence and Progression
  5. 2505
    “…Additional prevention efforts should be targeted toward adults who are immunocompromised, frail, and those living in lower socioeconomic quintiles. …”
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    Herpes zoster in older adults in Ontario, 2002–2016: Investigating incidence and exploring equity
  6. 2506
    “…During the COVID-19 pandemic, prolonged time until surgery and thus an increased rate of complications took a toll on frail patients with PFFs. This review aims to offer surgical guidelines for the treatment of PFFs in the elderly with a focus on pitfalls and challenges particularly relevant to frail patients.…”
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    Management of proximal femur fractures in the elderly: current concepts and treatment options
  7. 2507
    “…Observational, analytical, retrospective study using the database of a previous cross-sectional study containing information on 449 people aged 60 years and over, who participated in the ANDES-FRAIL project. The dependent variable was mobility, evaluated using the Short Physical Performance Battery; the independent variable was social support, evaluated using an item from the Edmonton Frail Scale. …”
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    Impacto del soporte social sobre la movilidad limitada en personas mayores de comunidades altoandinas peruanas
  8. 2508
    “…Frailty was present in 24.1% of the study sample (95% CI = 20.7–27.6) of whom 54.3% were found to be pre-frail and 21.6% were non-frail. The study variable most strongly associated with frailty was the female gender (OR = 20.54, 95% CI = 9.10–46.3). …”
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    Assessing Prevalence and Factors Related to Frailty in Community-Dwelling Older Adults: A Multinomial Logistic Analysis
  9. 2509
    “…We illustrate the approach using data from the SPRINT trial of antihypertensive intervention, comparing risk-benefit profiles for robust, pre-frail, and frail subpopulations, and in analysis of fall as a function of progressive risk factors. …”
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    A Novel Algorithm for Analysis of Multiple Endpoints Using Risk–Benefit Profiles
  10. 2510
    “…OBJECTIVE: This study aimed to assess the probability of reaching an adequate pharmacokinetic/pharmacodynamic (pK/pD) index for different cefepime dosages in frail patients with bacteremia treated in the emergency room. …”
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    Cefepime Dosing Requirements in Elderly Patients Attended in the Emergency Rooms
  11. 2511
    “…As such, LDMC is a well-tolerated treatment option for patients with mCRPC, including those who are older and frail. Furthermore, LDMC is considered more affordable than conventional mCRPC therapies. …”
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    Metronomic Chemotherapy for Advanced Prostate Cancer: A Literature Review
  12. 2512
    “…The KFACS participants were classified as robust or frail based on Fried’s frailty phenotype and excluded if they did not properly answer the questions, resulting in 1,066 robust and 165 frail participants. …”
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    Development of a Frailty Detection Model Using Machine Learning with the Korean Frailty and Aging Cohort Study Data
  13. 2513
    “…Based on the modified Fried frailty scale, the participants were divided into three categories: robust, pre-frail, and frail. A chi-square test (or Fisher’s test) examined the relationship between frailty categories and other variables. …”
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    Frailty and Associated Factors among the Elderly in Vietnam: A Cross-Sectional Study
  14. 2514
    “…OBJECTIVE: Patients with advanced diseases and frail older adults often face decisions regarding life-prolonging treatment. …”
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    Feasibility and effectiveness of tools that support communication and decision making in life-prolonging treatments for patients in hospital: a systematic review
  15. 2515
    “…At baseline, the urinary levels of these metabolites were significantly higher (i) in frail compared with non-frail patients, (ii) in persons with poorer FIM scores, and (iii) in persons with poorer compared SPPB scores. …”
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    (1)H NMR Urinary Metabolomic Analysis in Older Adults after Hip Fracture Surgery May Provide Valuable Information for Patient Profiling—A Preliminary Investigation
  16. 2516
    “…Frailty index (FI), based on 33 potential deficits, was used to categorize individuals as robust, pre-frail, or frail. RESULTS: A total of 18,010 older adults with diabetes were included in this study. …”
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    A study on the prevalence and related factors of frailty and pre-frailty in the older population with diabetes in China: A national cross-sectional study
  17. 2517
    “…Of the total group, 47 patients met criteria for ‘pre-frail’ and 10 met criteria for ‘frail’ using Fried criteria. …”
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    Frailty in Secure Forensic Mental Health Settings: A Study from Dundrum Hospital, Ireland
  18. 2518
    “…BACKGROUND: Availability of assisted PD (asPD) increases access to dialysis at home, particularly for the increasing numbers of older and frail people with advanced kidney disease. Although asPD has been widely used in some European countries for many years, it remains unavailable or poorly utilized in others. …”
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    Availability of assisted peritoneal dialysis in Europe: call for increased and equal access
  19. 2519
    “…Digital health technology has the potential to be useful for every field of cardiology, but notably in an office‐based setting with frequent contact with ambulatory older adults who may be pre‐frail or frail but who are still able to live at home. …”
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    Digital health in older adults for the prevention and management of cardiovascular diseases and frailty. A clinical consensus statement from the ESC Council for Cardiology Practice/Taskforce on Geriatric Cardiology, the ESC Digital Health Committee and the ESC Working Group on e‐Cardiology
  20. 2520
    “…BTX‐A likely has a higher risk of urinary tract infection and retention in older compared to younger populations, especially in the frail elderly. PTNS incurs the lowest risk, although adherence is poor, largely due to logistical burdens. …”
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    Third‐line therapy for overactive bladder in the elderly: Nuances and considerations
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