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  1. 2581
    “…Based on their calculated GFI, between 61% and 64% of the REACH II caregivers were frail. Frail caregivers and their care recipient were less likely to go to the emergency department (-0.110 coefficient; p = 0.004 95% CI -0.184 -0.035) and were less likely to be hospitalized overnight during the past 6 months (-0.121 coefficient; p=0.004; 95% CI -0.203 -0.040). …”
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    FRAILTY IN REACH II CAREGIVERS: A SECONDARY DATA ANALYSIS
  2. 2582
    “…Participants were also assessed using the Fried Phenotype Criteria (FC) and were classified into three groups: robust, pre-frail, and frail. Mean-shift clustering algorithm was used to operationalize the FI by identifying the cut-off point for each group. …”
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    OPERATIONALIZING THE FRAILTY INDEX BASED ON WEARABLE SENSOR TO ASSESS FUNCTIONAL PERFORMANCE IN OLDER ADULTS
  3. 2583
    “…As many frail older adults are discharging to their own home, clinicians need to pay more attention to them. …”
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    FACTORS ASSOCIATED WITH HOSPITAL-TO-HOME DISCHARGE: USING A DECISION TREE ANALYSIS
  4. 2584
    “…Associations of the cytokines and metabolites with grip strength, walking speed, falls and outcomes were assessed in young, robust, pre-frail and frail participants. Age and frailty status positively correlated with IL6, TNFα, TNFαR1, IL1β (p<0.0001). …”
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    ALTERED TRYPTOPHAN DEGRADATION LINKS CHRONIC INFLAMMATION TO FUNCTIONAL DECLINE & FRAILTY IN MICE AND HUMANS
  5. 2585
    “…The highest prevalence of frailty was observed for Bangladeshis, with 32.9% classified as frail (95% CI, 29.2‐36.7); and the lowest prevalence of 14.0% (95% CI, 12.6‐15.5) was observed for the Black ethnic group. …”
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    Ethnic differences in the prevalence of frailty in the United Kingdom assessed using the electronic Frailty Index
  6. 2586
    “…Older patients are categorized into three conceptual groups: ‘fit patients’ who can undergo the same standard treatment given to younger patients, ‘frail patients’ for whom best supportive or palliative care is indicated and ‘vulnerable patients’ who fall between the fit and frail categories. …”
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    Geriatric Research Policy: Japan Clinical Oncology Group (JCOG) policy
  7. 2587
    “…We aimed to determine the prevalence of frailty and its association with cognitive status and functional fitness among pre-frail and frail Malaysian older adults residing in institutions on the west coast of Peninsular Malaysia. …”
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    Prevalence of Frailty and Its Association with Cognitive Status and Functional Fitness among Ambulating Older Adults Residing in Institutions within West Coast of Peninsular Malaysia
  8. 2588
    “…RESULTS: of 2,865 participants, 261 were frail at baseline and 423 became frail during follow-up. …”
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    Investigation of a possible association of potentially inappropriate medication for older adults and frailty in a prospective cohort study from Germany
  9. 2589
    “…Most patients (82%) with AF were frail and 53% were severely frail. CONCLUSION: Repeated screening in geriatric patients has a five times higher diagnostic yield than usual care. …”
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    Opportunistic screening for atrial fibrillation with a single lead device in geriatric patients
  10. 2590
    “…The research and development of pharmaceutical intervention is insufficient for the frail older adults, especially in preclinical stage for the frail individuals with osteoporosis. …”
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    Allicin Reversed the Process of Frailty in Aging Male Fischer 344 Rats With Osteoporosis
  11. 2591
    “…We suggest ways to define an integrated strategy that could involve both public institutional entities and the private sector to safeguard frail individuals and mitigate the impact of the outbreak.…”
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    The potential long-term impact of the COVID-19 outbreak on patients with non-communicable diseases in Europe: consequences for healthy ageing
  12. 2592
    “…DESIGN: We profiled the gut microbiota in 612 non-frail or pre-frail subjects across five European countries (UK, France, Netherlands, Italy and Poland) before and after the administration of a 12-month long MedDiet intervention tailored to elderly subjects (NU-AGE diet). …”
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    Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries
  13. 2593
    “…These data may help inform health care planners and targeted interventions and appropriate management for the frail older person.…”
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    The Clinical Frailty Scale: Estimating the Prevalence of Frailty in Older Patients Hospitalised with COVID-19. The COPE Study
  14. 2594
    “…The use of implementation research methods and case study design are recommended as an additional evaluation approach for researchers to consider, alongside suggested ways of improving methods of data collection with frail populations and cost analysis.…”
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    Advancing integrated care evaluation in shifting contexts: blending implementation research with case study design in project SUSTAIN
  15. 2595
    “…MEASUREMENTS AND MAIN RESULTS: We conducted 21 semi-structured interviews and identified five key themes: (1) prognostic uncertainty (2) subjectivity of good versus poor outcome (3) perceived inappropriate care (PIC) situations (including for frail elderly patients) (4) challenging nature of decision-making (5) clinician distress. …”
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    Clinicians’ Perceptions of the Appropriateness of Neurocritical Care for Patients with Spontaneous Intracerebral Hemorrhage (ICH): A Qualitative Study
  16. 2596
    “…Although many guidelines mentioned frailty, only three gave specific thresholds and targets for frail older adults. The quality of the guidelines was not related with the recommended targets. …”
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    Systematic Review of Guidelines on Antihypertensive Treatment in Older Adults: SPRINTing to More Heterogeneity?
  17. 2597
    “…To overcome these barriers, we conducted a feasibility study to evaluate a home-based exercise program with telephone coaching to improve mobility in frail older adults. Four non-demented, frail community-dwelling older adults were taught one of two exercise routines at our research center. …”
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    Home-Based Exercise Program With Telephone Coaching: A Feasibility Study
  18. 2598
    “…RESULTS: 62.1% of the participants were frail, 29.3% were prefrail, and 8.6% were robust. …”
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    Frailty assessment of older adults, first-time applicants of public home care service in Norway
  19. 2599
    “…This systematic review could help the surgeon in the adoption of frailty indexes, before the operation, and in preventing complications in frail patients.…”
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    The Impact of Frailty on Spine Surgery: Systematic Review on 10 years Clinical Studies
  20. 2600
    “…However, because it concerns an elderly and often frail population, (extensive) surgery may not always be feasible due to the associated morbidity. …”
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    Merkel Cell Carcinoma: New Trends
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