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  1. 2781
    “…While functional gains are unlikely to change discharge destination in this frail group, they can contribute to improvements in HRQoL. …”
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    Health-related Quality of Life among hospitalized older people awaiting residential aged care
  2. 2782
    “…In spite of frail conditions, eleven patients could be followed during 18 months. …”
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    Intraprostatic Botulinum Toxin Type A injection in patients with benign prostatic enlargement: duration of the effect of a single treatment
  3. 2783
    “…METHODOLOGY/PRINCIPAL FINDINGS: To assess potential mitochondrial genetic contributions to the likelihood of frailty, mitochondrial DNA (mtDNA) variation was compared in frail and non-frail older adults. Associations of selected SNPs with a muscle strength phenotype were also explored. …”
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    Polymorphisms in the Mitochondrial DNA Control Region and Frailty in Older Adults
  4. 2784
    “…Whole-body vibration (WBV) training is a type of exercise that seems beneficial in frail older persons to improve their functional mobility, but the evidence is inconclusive. …”
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    Whole body vibration for older persons: an open randomized, multicentre, parallel, clinical trial
  5. 2785
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    miR-127 Protects Proximal Tubule Cells against Ischemia/Reperfusion: Identification of Kinesin Family Member 3B as miR-127 Target
  6. 2786
    “…Up to one-third of the hospitalized frail elderly loses independent functioning in one or more activities of daily living as a result of the ‘hostile environment’ that is present in the acute hospitals. …”
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    Moving Towards the Age-friendly Hospital: A Paradigm Shift for the Hospital-based Care of the Elderly
  7. 2787
    por Larsen, Torben, Santana, Silvina
    Publicado 2012
    “…OBJECTIVES: This project of international collaboration assesses integrated home care (IHC) for frail elder somatic patients as compared to usual hospital care. …”
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    Workshop: health technology assessment of integrated home care for frial elder somatic patients
  8. 2788
    “…The predictive validity of these scales for mortality varied: for instance, hazard ratios/odds ratios (95% confidence interval) for mortality risk for frail relative to non-frail people ranged from 1.21 (0.78; 1.87) to 6.03 (3.00; 12.08) for the Phenotype of Frailty and 1.57 (1.41; 1.74) to 10.53 (7.06; 15.70) for the Frailty Index. …”
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    Measures of frailty in population-based studies: an overview
  9. 2789
    por Liao, Chun-Hou, Kuo, Hann-Chorng
    Publicado 2015
    “…However, increased risk of larger postvoid residual (PVR) urine and lower long-term success rates were noted in frail elderly patients; around 11% had acute urinary retention, while 60% had PVR urine volume >150 mL after treatment. …”
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    Practical Aspects of Botulinum Toxin-A Treatment in Patients With Overactive Bladder Syndrome
  10. 2790
    “…CONCLUSION: Psychological treatment is a feasible option for frail elderly with depressive symptoms. However, important questions about efficacy, generalizability, safety and cost-effectiveness remain.…”
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    Psychological Treatment of Depression in People Aged 65 Years and Over: A Systematic Review of Efficacy, Safety, and Cost-Effectiveness
  11. 2791
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    Clinical Subgroups in Bilateral Meniere Disease
  12. 2792
    “…The study population consisted of 80 HIV + men with a median age of 59 (IQR, 56–65), and most had an undetectable viral load (92%). 24% were frail, and 76% were non-frail. Frailty was associated with elevated Glucose transporter-1 (Glut1) expression on the total monocytes (p = 0.04), increased plasma levels of innate immune activation marker sCD163 (OR, 4.8; CI 1.4–15.9, p = 0.01), phosphatidylethanolamine PE(36:3) (OR, 5.1; CI 1.7–15.5, p = 0.004) and triacylglycerol TG(16:1_18:1_18:1) (OR, 3.4; CI 1.3–9.2, p = 0.02), but decreased expression of GM3 ganglioside, GM3(d18:1/18:0) (OR, 0.1; CI 0.0–0.6, p = 0.01) and monohexosylceramide HexCerd(d18:1/22:0) (OR, 0.1; CI 0.0–0.5, p = 0.004). …”
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    Immunometabolic and Lipidomic Markers Associated With the Frailty Index and Quality of Life in Aging HIV+ Men on Antiretroviral Therapy
  13. 2793
    “…Frail participants also showed a higher presence of carotid plaques and CACs. …”
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    Frailty and Risk of Cardiovascular Diseases in Older Persons: The Age, Gene/Environment Susceptibility-Reykjavik Study
  14. 2794
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    Conserved Bacterial-Binding Peptides of the Scavenger-Like Human Lymphocyte Receptor CD6 Protect From Mouse Experimental Sepsis
  15. 2795
    “…Of 40 083 patients, 8803 (22%) were frail. At 4±2 years of follow‐up, age‐ and sex‐standardized mortality rate per 1000 person‐years was higher in frail (33; 95% confidence interval, 29–36) compared with nonfrail (22; 95% confidence interval, 19–24) patients. …”
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    Association of Frailty and Long‐Term Survival in Patients Undergoing Coronary Artery Bypass Grafting
  16. 2796
    “…Older adults, especially frail older adults, form the main users of medical and social care services. …”
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    Frailty syndrome: implications and challenges for health care policy
  17. 2797
    “…AST was not available in patients significantly more dependent in ADL and more frail. OH was diagnosed in 57 (16.2%) patients, significantly more frequently in men (systolic- 45,5%, systolic-diastolic-40,0%). …”
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    Health and Functional Determinants of Orthostatic Hypotension in Geriatric Ward Patients: A Retrospective Cross Sectional Cohort Study
  18. 2798
    por Xie, Boqin
    Publicado 2019
    “…These findings notably imply to the development of interventions for older frail adults from the neighborhood perspective.…”
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    SOCIAL COHESION AFFECTS THE ASSOCIATION BETWEEN FRAILTY AND DISABILITY IN COMMUNITY-DWELLING OLDER ADULTS
  19. 2799
    “…By using an established frailty definition, individuals with three or more of the following deficits were considered frail: 1) body mass index less than or equal to 18.5, 2) low grip strength, 3) severe fatigue, 4) slow 4‐m walking speed, and 5) low physical activity. …”
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    The Impact of Frailty on Changes in Physical Function and Disease Activity Among Adults With Rheumatoid Arthritis
  20. 2800
    “…The aim of this study was to determine the FA profile and pro-antioxidant status in sarcopenic frail elderly patients enrolled in a nutritional and physical activity program and to evaluate their correlation with clinical markers. …”
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    Fatty Acid Profile and Antioxidant Status Fingerprint in Sarcopenic Elderly Patients: Role of Diet and Exercise
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