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  1. 2841
    “…CONCLUSIONS: MPI could help to identify less frail older adults hospitalized for COVID-19 who could benefit more from remdesivir treatment in terms of long-term survival.…”
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    The Role of Multidimensional Prognostic Index to Identify Hospitalized Older Adults with COVID-19 Who Can Benefit from Remdesivir Treatment: An Observational, Prospective, Multicenter Study
  2. 2842
    “…In addition, after adjusting for age, gender, BMI, ALT, sCr, and score on the FRAIL scale, the multivariate linear regression analysis showed that TT3 was positively associated with muscle strength and negatively associated with sarcopenia risk. …”
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    TT3, a More Practical Indicator for Evaluating the Relationship Between Sarcopenia and Thyroid Hormone in the Euthyroid Elderly Compared with FT3
  3. 2843
    “…BACKGROUND: Emergency departments are chaotic environments in which complex, frail older persons living in the community and residential aged care facilities are sometimes subjected to prolonged emergency department lengths of stay, excessive tests and iatrogenic complications. …”
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    A structure, process and outcome evaluation of the Geriatric Emergency Department Intervention model of care: a study protocol
  4. 2844
    “…An upright upper trunk in Fowler’s position might help to reduce orthostatic stress and facilitate routine activities and conversation in frail patients.…”
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    Assessment of effects of differences in trunk posture during Fowler’s position on hemodynamics and cardiovascular regulation in older and younger subjects
  5. 2845
    “…It was used both as a continuous score and as a categorical variable, defining ‘most frail’ a FI > 0.45. FI change across transplant (deltaFI, ΔFI) was calculated as the difference between year 1 FI (FI–Y1) and pre-transplant FI (FI–t0). …”
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    A frailty index predicts post-liver transplant morbidity and mortality in HIV-positive patients
  6. 2846
    “…BACKGROUND: In the United States, home-based primary care (HBPC) is increasingly proposed as a means of enabling frail elders to remain at home for as long as possible, while still receiving needed medical care. …”
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    The effects of home-based primary care on Medicare costs at Spectrum Health/Priority Health (Grand Rapids, MI, USA) from 2012-present: a matched cohort study
  7. 2847
    “…Objective frailty tools identified an even higher risk group for late mortality (HR 2.63, 95% CI 1.87–3.70, P < 0.001). Frail individuals undergoing TAVI have a mortality rate of 34 deaths per 100 patient years, compared with 19 deaths per 100 patient years in non-frail patients. …”
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    The relationship between preoperative frailty and outcomes following transcatheter aortic valve implantation: a systematic review and meta-analysis
  8. 2848
    “…METHODS: Randomized parallel group multicenter clinical trial located in primary care setting, among non-dependent and pre-frail patients > 70 years old, including 190 patients (95 intervention, 95 control group). …”
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    Effectiveness of an intervention in multicomponent exercise in primary care to improve frailty parameters in patients over 70 years of age (MEFAP-project), a randomised clinical trial: rationale and study design
  9. 2849
    “…RESULTS: 1768 (35.1%) participants completed the questionnaire. 68.9% of the respondents was frail on one or multiple domains and 51.6% of the respondents was frail based on the total score on the TFI. …”
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    A cross sectional study on the different domains of frailty for independent living older adults
  10. 2850
    “…When the question involves other frail people in various disease areas, information seems relevant for 60.1% of GPR considering patient with cancer or malignant hematologic disease and for 56.2% about patients affected by neurodegenerative disease. …”
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    Advance directives in France: do junior general practitioners want to improve their implementation and usage? A nationwide survey
  11. 2851
    “…Based on this, an 8-element frailty score with a 0–9 (least frail–most frail) scale was developed. A total of 142 patients, 54% women, mean age 83 (standard deviation 4) years, with severe and symptomatic aortic stenosis were assessed. …”
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    A novel geriatric assessment frailty score predicts 2-year mortality after transcatheter aortic valve implantation
  12. 2852
    “…Participants with serum 25(OH)D status < 50 nmol/L were about two times more likely to be frail compared to participants with serum 25(OH)D status ≥ 50 nmol/L. …”
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    The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults
  13. 2853
    “…Participants were dichotomized as frail or non-frail based on a validated frailty index calculated as the proportion of the number of deficits present to a total of 45 possible deficits ascertained in NHANES. …”
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    Body weight, frailty, and chronic pain in older adults: a cross-sectional study
  14. 2854
    “…METHODS: A cross sectional study in adult and older patients with body mass index equal to or lower than 35 kg/m(2) was carried out. BIA and Clinical Frail Scale scoring were performed during pre-operative evaluation. …”
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    Bioelectrical impedance analysis of body composition for the anesthetic induction dose of propofol in older patients
  15. 2855
    “…Efforts should be made to identify frail patients with CKD so that management strategies can be offered that aim to improve morbidity, mortality and patient-reported outcomes, including HRQOL and fatigue.…”
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    Frailty is independently associated with worse health-related quality of life in chronic kidney disease: a secondary analysis of the Frailty Assessment in Chronic Kidney Disease study
  16. 2856
    “…The secondary outcomes are changes in cognition scores, 24-hour movement behaviour, grip strength, weight, percentage robust, pre-frail and frail classification, rate of adverse medicine events, health-related quality of life and health resource use. …”
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    Reducing medicine-induced deterioration and adverse reactions (ReMInDAR) trial: study protocol for a randomised controlled trial in residential aged-care facilities assessing frailty as the primary outcome
  17. 2857
    “…The cohort included 138 (51%) robust, 87 (32.2%) vulnerable and 45 (16.7%) frail patients. The association between PIMs and LOS was not significant for the robust and frail subgroups. …”
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    Potentially Inappropriate Medication Use in Older Adults in the Preoperative Period: A Retrospective Study of a Noncardiac Surgery Cohort
  18. 2858
    “…This underlines the importance of focusing also on psychosocial well-being of frail older subjects to remain or promote their resilience.…”
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    Psychosocial resources related to survival among non-robust community-dwelling older people: an 18-year follow-up study
  19. 2859
    “…Participants were stratified into frail and non-frail using the Johns Hopkins (ACG) frailty-defining diagnosis indicator. …”
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    Impact of frailty on inpatient outcomes in thyroid cancer surgery: 10-year results from the U.S. national inpatient sample
  20. 2860
    por Dudel, Christian, Myrskylä, Mikko
    Publicado 2020
    “…We replicate the prior finding that frail individuals have longer life expectancy in disability. …”
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    Estimating the number and length of episodes in disability using a Markov chain approach
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