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  1. 1481
    “…A pacemaker generator change for a frail woman was performed with a direct oral anticoagulant. …”
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    Exposed Hematoma After Pacemaker Generator Change
  2. 1482
    “…The frailty phenotype was categorized as robust, pre-frail or frail. Multimorbidity and a frailty indicator (approximating the deficit accumulation index) were derived from claims. …”
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    Frailty Phenotype and Healthcare Costs in Women in Late Life: The SOF study
  3. 1483
    “…The MSTN levels were significantly higher in frail participants than in participants who were not frail (2.93 ± 1.35 ng/mL vs 2.24 ± 0.84 ng/mL; P = 0.018). …”
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    A Prospective Case-Control Study Examining the Relationship Between Frailty and Serum Myostatin in Older Persons with Chronic Heart Failure
  4. 1484
    “…There was no significant difference in mortality rate between frail and non-frail aSAH patients, but this analysis only included two studies and should be interpreted cautiously. …”
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    Frailty as a Predictor of Outcomes in Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis
  5. 1485
    “…Various kinds of nutrient intakes, including three major nutrients, minerals, and vitamins in frail men, according to KCL, were the lowest. By contrast, there were no differences in nutrient intake between the robust, prefrail, and frail female groups according to KCL. …”
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    The Relationship between Dietary Habits and Frailty in Rural Japanese Community-Dwelling Older Adults: Cross-Sectional Observation Study Using a Brief Self-Administered Dietary History Questionnaire
  6. 1486
    “…Seventy‐three subjects were frail; the mean cystatin C levels in the frail and non‐frail groups were 1.28 mg/L (±0.39) and 1.12 mg/L (±0.27), respectively, and the difference was significant (P < 0.05). …”
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    Raised serum cystatin C can be a potential biomarker of frailty detected by cumulative deficit model
  7. 1487
    “…METHODS: We collected data on the residents’ background information, HRQoL by 15D, nutritional status by Mini Nutritional Assessment (MNA), frailty status (Fried’s phenotype criteria; pre-frail: 1–2 criteria and frail: 3–5) and energy intake (one- or two-day food records). …”
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    Associations Between Nutritional Status, Frailty and Health-Related Quality of Life Among Older Long-Term Care Residents in Helsinki
  8. 1488
    “…Protein consumption was associated with frailty status only in participants identified as frail according to the mFP. In addition, protein and BCAA intake was found to be greater in robust and pre-frail participants relative to their frail counterparts. …”
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    Protein-Related Dietary Parameters and Frailty Status in Older Community-Dwellers across Different Frailty Instruments
  9. 1489
    “…Significant decreases in measures of oxygen consumption were observed for frail humans but not in animal models. Conversely, no differences between frail and nonfrail humans were observed for apoptosis and autophagy, in contrast to animal models. …”
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    A systematic review and meta‐analysis of studies that have evaluated the role of mitochondrial function and iron metabolism in frailty
  10. 1490
    “…Comorbidity burden was higher among frail men, whereas social factors were poorer between frail women. …”
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    Frailty among chronic kidney disease patients on the kidney transplant waiting list: the sex–frailty paradox
  11. 1491
    “…Patients with a mean CFS value of 5 or higher were classified into the frail group. The 2-year survival rates or hospitalization-free rates after the initiation of dialysis were compared between the frail (mean CFS score ≥ 5) and non-frail (mean CFS score < 5) groups. …”
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    Clinical frailty assessment might be associated with mortality in incident dialysis patients
  12. 1492
    “…Hence, the identification of frail patients with gastrointestinal cancer would improve cancer treatment outcomes. …”
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    Frailty and surgical outcomes in gastrointestinal cancer: Integration of geriatric assessment and prehabilitation into surgical practice for vulnerable patients
  13. 1493
    por Toba, Ayumi, Ishikawa, Joji
    Publicado 2023
    “…Mortality is reported to be high among frail patients with lower BP, raising questions about appropriate BP targets for frail patients. …”
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    Current topics of frailty in association with hypertension and other medical conditions
  14. 1494
    “…Odds of hospitalisation in the last 12 months, and having falls in the past 2 years, were two times as high in frail adults compared with non-frail adults. Frail middle-aged and older adults had 33% and 39% higher odds, respectively, of having poor cognition than non-frail adults. …”
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    Frailty among middle-aged and older women and men in India: findings from wave 1 of the longitudinal Ageing study in India
  15. 1495
    “…Among 4923 TAVI patients, meta-analysis showed 12-month mortality rates of 19.1% for the frail cohort versus 9.8% for the non-frail cohort (RR 2.53 (1.63 to 3.95), p<0.001, I(2)=83%). …”
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    Clinical Frailty Scale as a predictor of adverse outcomes following aortic valve replacement: a systematic review and meta-analysis
  16. 1496
    “…However, there is a need for additional evidence to guide decision-making for the care of frail patients since frail persons are frequently excluded from studies, the differential impact of frailty is often not examined in clinical trials and few large-scale clinical trials examining frail cohorts have been conducted. …”
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    Frailty measurement and outcomes in interventional studies: protocol for a systematic review of randomised control trials
  17. 1497
    “…Furthermore, 199 (20.3%) would be classified as at least severely frail (CFS score 7–9), but 74.9% of this group is not severely frail according to the ID‐frailty index. …”
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    Determining Frailty in People With Intellectual Disabilities in the COVID‐19 Pandemic
  18. 1498
    “…The frail had significantly shorter EFS compared with the fit and intermediate group in our frailty index (fit vs. intermediate: HR = 1.34, 95% CI = 0.92–1.96, P = 0.132; fit vs. frail: HR = 2.06, 95% CI = 1.40–3.02, P < 0.001; and intermediate vs. frail: HR = 1.53, 95% CI = 1.22–1.92, P < 0.001, respectively). …”
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    Development of a new clinical index to easily assess frailty of elderly patients with multiple myeloma in Asian population
  19. 1499
    “…RESULTS: Fifty-six eligible participants were recruited, including 12 non-frail (age = 76.92 ± 7.32 years), and 40 pre-frail (age = 80.53 ± 8.12 years), and four frail individuals (age = 88.25 ± 4.43 years). …”
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    Frailty assessment using a novel approach based on combined motor and cardiac functions: a pilot study
  20. 1500
    “…Frailty was measured using a frailty index (FI) (scored 0.0–1.0) and stratified into tertiles: ‘frail’ (≥ 0.22), ‘pre-frail’ (0.13–0-21) and ‘non-frail’ (≤ 0.12). …”
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    A “snap-shot” visual estimation of health and objectively measured frailty: capturing general health in aging older women
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