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  1. 1581
    “…While the presence of frailty reduced the survival rate in women, no effect was observed in men. Importantly, frail women showed higher survival rates than did both frail and no frail men. …”
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    Inter-relationships between Gender, Frailty and 10-Year Survival in Older Italian Adults: an observational longitudinal study
  2. 1582
    “…ECOG PS (n = 1618) was investigated in frailty groups: frail (49%) and nonfrail (51%). Frail patients experienced worse progression-free and overall survival vs nonfrail patients. …”
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    A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial
  3. 1583
    “…The increasing number of frail elderly people in our aging society is becoming problematic: about 11% of community‐dwelling older persons are frail and another 42% are pre‐frail. …”
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    An opinion paper on the maintenance of robustness: Towards a multimodal and intergenerational approach using digital twins
  4. 1584
    por Wang, Tiantian, Zhao, Yanwei, Guo, Aimin
    Publicado 2020
    “…Dysphagia was more prevalent in frail and pre-frail patients (48.9% and 32.4%, respectively) than those who were non-frail (13.6%). …”
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    Association of swallowing problems with frailty in Chinese hospitalized older patients
  5. 1585
    “…RESULTS: A total of 13.39% of the patients were pre-frail and 17.32% were frail. Frail individuals had a shorter hospital stay, less ICU admission, higher mortality and delirium, with statistical significance. …”
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    Outcomes of hospitalized patients with COVID-19 according to level of frailty
  6. 1586
    “…Within the 30 complications, 16 occurred in the non-frail group (8%) and 14 in frail patients (24.5%), (p = 0.02). …”
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    La fragilidad como índice predictor en cirugía de columna
  7. 1587
    “…We identified 2 miRNAs able to significantly differentiate frail patients from robust subjects. Both miR-101-3p and miR-142-5p were found to be downregulated in the frail vs. robust group. …”
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    miRNome Profiling Detects miR-101-3p and miR-142-5p as Putative Blood Biomarkers of Frailty Syndrome
  8. 1588
    “…Patients were identified as “non-frail” (robust) or “prefrail/frail” if they fulfilled at least one frailty criteria. …”
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    Plasma Aromatase Activity Index, Gonadotropins and Estrone Are Associated with Frailty Syndrome in Post-Menopausal Women with Breast Cancer
  9. 1589
    “…This study aims to explore the experiences among frail older adults who did not complete an advance directive after an ACP conversation. …”
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    Experiences of Older Adults with Frailty Not Completing an Advance Directive: A Qualitative Study of ACP Conversations
  10. 1590
    “…A study was made of the effect of the PROMUFRA multicomponent frailty program upon physical frailty, kinanthropometry, pain and muscle function parameters in frail and pre-frail community-dwelling older people. …”
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    Frailty Status Improvement after 5-Month Multicomponent Program PROMUFRA in Community-Dwelling Older People: A Randomized Controlled Trial
  11. 1591
    “…RESULTS: Overall, 31.9% were frail, 58.3% were prefrail, and 9.8% were robust. …”
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    Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study
  12. 1592
    “…BACKGROUND: U.S. nursing homes provide long-term care to over 1.2 million older adults, 60% of whom were physically frail and 68% had moderate or severe cognitive impairment. …”
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    Trajectories of physical frailty and cognitive impairment in older adults in United States nursing homes
  13. 1593
    “…Frailty was identified as an important barrier to anticoagulant therapy with 52% of the frail population anticoagulated vs 67% non‐frail. …”
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    Frailty and oral anticoagulant prescription in adults with atrial fibrillation: A systematic review
  14. 1594
    por Alqahtani, Bader
    Publicado 2023
    “…A cutoff score of 6 or more medications distinguished frail from non-frail. Addressing polypharmacy in the older population might ameliorate the impact of physical frailty.…”
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    Number of medications and polypharmacy are associated with frailty in older adults: results from the Midlife in the United States study
  15. 1595
    “…AIMS: Although up to 25% of older adults are frail, assessing frailty can be difficult, especially in registry data. …”
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    Comparison of two different frailty scales in the longitudinal Swedish Adoption/Twin Study of Aging (SATSA)
  16. 1596
    “…Serum sirtuins level in mean+SD; SIRT1 (nonfrail –4.67 ± 0.48 ng/μL; frail – 3.72 ± 0.48 ng/μL; P < 0.0001), SIRT2 (nonfrail – 15.18 ± 2.94 ng/μL; frail – 14.19 ± 2.66 ng/μL; P = 0.016), and SIRT3 (nonfrail-7.72 ± 1.84 ng/μL; frail – 6.12 ± 0.97 ng/μL; P < 0.0001) levels were significantly lower among frail patients compared with the nonfrail. …”
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    Identification of serum sirtuins as novel noninvasive protein markers for frailty
  17. 1597
    “…The pooled RR of AKI after TAVR among the frail patients was 1.19 (95% CI 0.97–1.46, I(2) = 0), compared with non-frail patients. …”
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    Association of frailty status with acute kidney injury and mortality after transcatheter aortic valve replacement: A systematic review and meta-analysis
  18. 1598
    “…Slowness was a strong predictor of cognitive change in both frail and non-frail participants, especially for executive function (frail: Cohen’s d per year=-0.16, SE= 0.02; non-frail: Cohen’s d per year=-0.15, SE= 0.02). …”
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    PHYSICAL FRAILTY AND ITS ASSOCIATION WITH COGNITION: THE PREDICTIVE VALUE OF A SYNDROME BEYOND ITS COMPONENT PARTS
  19. 1599
    “…Of a total of 1269 transitions, 692 remained the same; the models used 549 transitions; 44% from robust to pre-frail or pre-frail to frail. Those recovering from pre-frail to robust had lower disease burden and higher nutritional intake. …”
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    Dietary Protein and Transitions Between Frailty States and to Death in Advanced Age: LiLACS NZ
  20. 1600
    “…Participants mean age was 68.38 (SD=8.49) years, 57.50% (n=617) Caucasian, 69.34% (n=744) non-Hispanic, 95.81% (n=1,028) male, and 36.72% (n=394) frail. 11.84%(n=127) screened positive for MCI and 15.38% (n=165) for dementia. 689 (75.88%) veterans were at high risk for dementia of whom 426 (61.83%) were non-frail and 263 (38.17%) were frail. …”
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    Dementia Risk in Older Veterans With Frailty: A Cross-Sectional Study
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