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  1. 1661
    “…Propensity scoring yielded similar findings. Compared with non-frail participants not prescribed statins, the adjusted HR for institutionalisation for non-frail participants prescribed statins was 1.43 (95% CI 0.81 to 2.51); for frail participants not prescribed statins, it was 2.07 (95% CI 1.11 to 3.86) and for frail participants prescribed statins, it was 4.34 (95% CI 2.02 to 9.33). …”
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    Statin use and clinical outcomes in older men: a prospective population-based study
  2. 1662
    “…Seventy (29.3%) patients were classified as frail (EFS ≥ 3). In non-frail patients, the EQ-5D-5 L index did not change (0.71(± 0.22) to 0.68(± 0.33) points, P = 0.22); in frail patients, the EQ-5D-5 L index decreased from 0.55(±0.26) to 0.44 points (±0.33) (P = 0.022). …”
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    Impact of frailty on health-related quality of life 1 year after transcatheter aortic valve implantation
  3. 1663
    “…The target sample will consist of 256 community-dwelling non-frail and pre-frail adults of 65 years or older with an increased risk of falls. …”
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    The (cost-)effectiveness of an implemented fall prevention intervention on falls and fall-related injuries among community-dwelling older adults with an increased risk of falls: protocol for the in balance randomized controlled trial
  4. 1664
    “…BACKGROUND: Patients with end-stage renal disease are known to be particularly frail, and the cause is still widely seen as being directly related to specific factors in renal replacement therapy. …”
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    A Pilot Observational Study Assessing Long-Term Changes in Clinical Parameters, Functional Capacity and Fall Risk of Patients With Chronic Renal Disease Scheduled for Hemodialysis
  5. 1665
    “…The prevalence of robust, prefrail, and frail patients was 5%, 36.9%, and 58.1%, respectively. …”
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    Potentially Inappropriate Medications among Elderly with Frailty in a Tertiary Care Academic Medical Centre in Saudi Arabia
  6. 1666
    “…Frailty was associated with mortality (pre-frail: HR = 1.48; p = 0.02 and frail: HR = 1.68; p = 0.03), disability (pre-frail: β = 5.02; p < 0.01; frail: β = 13.29; p < 0.01) and quality of life (pre-frail: β = − 2.23; p < 0.01; frail: β = − 4.38; p < 0.01). …”
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    Disability, quality of life and all-cause mortality in older Mexican adults: association with multimorbidity and frailty
  7. 1667
    “…We used the SPPB to capture both a categorical score with frailty categories assigned as 0–6 (frail), 7–9 (pre-frail), and 10–12 (non-frail) and continuous score. …”
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    Evaluating frailty in Medicaid Home and Community-based Services clients: a feasibility and comparison study between the SHARE-FI and SPPB
  8. 1668
    “…For total quality‐of‐life, the odds of being in the group with a median score or more decreased for frail older people (OR 0.30) versus non‐frail and increased for those with medical insurance from employer versus basic (OR 2.30) and those doing exercise ≥30 min 3 days/week or more versus less (OR 2.12). …”
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    Associations between frailty, sociodemographic characteristics and quality‐of‐life among community‐dwelling older adults: A cross‐sectional study
  9. 1669
    “…Fifty (33.1%) were identified as non-frail, 49 (32.5%) as pre-frail, and 52 (34.4%) as frail by SHARE-FI. …”
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    Turkish version of the SHARE-Frailty Instrument for primary care: reliability and validity in the nursing home setting
  10. 1670
    “…Exercise programs that optimize the health of frail older adults seem to be different from those recommended for healthy older adults. …”
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    The Effectiveness of Exercise Interventions for the Management of Frailty: A Systematic Review
  11. 1671
    “…A prevalence of 21.8% (95% CI 17.4–26.9) was established when both frail and pre-frail conditions were included, and a prevalence of 3.2% (95% CI 1.7–5.9) if only frail individuals were considered. …”
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    Prevalence of Cognitive Frailty, Do Psychosocial-Related Factors Matter?
  12. 1672
    “…Our goal was to understand the factors associated with wellness among First Nations adults in Ontario who were considered frail. METHODS: Using the First Nations Regional Health Survey, we created a profile of First Nations adults (aged 45+) who were categorized as “frail” (weighted sample size = 8121). …”
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    Wellness in the Face of Frailty Among Older Adults in First Nations Communities
  13. 1673
    “…Frailty was assessed using the Cardiovascular Health Study criteria, with pre-frail and frail participants defined as frail and the other participants categorized into the robust group. …”
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    Activity diversity is associated with the prevention of frailty in community-dwelling older adults: The Otassha Study
  14. 1674
    “…We propose an effective model for managing vaccinations in frail patients in a specialist hospital setting.…”
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    MAURIVAX: A Vaccination Campaign Project in a Hospital Environment for Patients Affected by Autoimmune Diseases and Adult Primary Immunodeficiencies
  15. 1675
    “…The purpose of our study is to examine the minimal clinically important difference (MCID) for the 6-minute walk distance (6MWD) among frail Asian older adults. METHODS: Data from the “Evaluation of the Frails’ Fall Efficacy by Comparing Treatments” study were analyzed. …”
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    The minimal clinically important difference of six-minute walk in Asian older adults
  16. 1676
    “…BACKGROUND: Average life expectancy is rising, resulting in increasing numbers of elderly, frail individuals presenting with coronary artery disease and requiring percutaneous coronary intervention (PCI). …”
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    Impact of frailty on outcomes after percutaneous coronary intervention: a prospective cohort study
  17. 1677
    “…RESULTS: One thousand two hundred and eighty persons were recruited; 52 deaths were reported at 1 year of follow-up (robust 1.8%, frail 10.1% and very frail 19.1%, P < 0.001). The mean rate of use of hospital services was 692.2 per 1000 observation/year (robust 589.5, frail 1191.1 and very frail 848.4, P < 0.001). …”
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    Frailty as a predictor of mortality and hospital services use in older adults: a cluster analysis in a cohort study
  18. 1678
    “…The FRAGIRE, FRAIL Scale, Edmonton Frail Scale and IVCF-20 instruments were the most frequently analyzed in relation to clinimetric properties. …”
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    Instruments for the detection of frailty syndrome in older adults: A systematic review
  19. 1679
    “…CONCLUSIONS: Frailty is comparatively common in older patients attending physiotherapy care in Germany, with one out of three individuals being frail and every second individual being physically frail or prefrail. …”
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    Prevalence of frailty in older adults in outpatient physiotherapy in an urban region in the western part of Germany: a cross-sectional study
  20. 1680
    “…We applied untargeted, comprehensive LC-MS metabolomic analysis to human blood from 19 frail and nonfrail elderly patients who were clinically evaluated using the Edmonton Frail Scale, the MoCA-J for cognition, and the TUG for mobility. …”
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    Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility
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