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  1. 1921
    “…NTE MM being a quite heterogeneous population, there are still a number of groups of patients that are in need of more efficient therapy, avoiding unnecessary toxicity, particularly for the frail patients. The use of triplet regimen with a melphalan-prednisone (MP) backbone has long been the standard of care for NTE MM, often dedicated to non-frail patients. …”
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    Three Drug Combinations in the Treatment of Fit Elderly Multiple Myeloma Patients
  2. 1922
    “…Falls are an important health threat among frail older people. Physicians are often the first to contact for health issues and can be seen as designated professionals to provide fall prevention. …”
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    Fall Prevention in Dutch Physician Practices: A Descriptive Study
  3. 1923
    “…However, little is known about how older people understand and perceive the term “frailty”, and what it means for them to be designated as frail. To address this concern, a scoping review was undertaken to map the breadth of primary research studies that focus on community-dwelling older adults’ perceptions and understanding of frailty language, as well as explore the potential implications of being classified as frail. …”
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    Perceptions and Understandings of Frailty Language: A Scoping Review
  4. 1924
    “…The COVID-19 pandemic has disproportionately impacted frail older adults, especially residents of long-term care (LTC) facilities. …”
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    Considering Frailty in SARS-CoV-2 Vaccine Development: How Geriatricians Can Assist
  5. 1925
    “…Frailty status was assessed using the Edmonton Frail Scale (EFS). Sarcopenia was defined due to the EWGSOP2 criteria and ultrasonography was used to evaluate muscle mass. …”
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    Impact of frailty and ultrasonography-based sarcopenia on the development of postoperative complications in gastrointestinal cancer patients
  6. 1926
    “…Several studies reported the significant benefits of virtual reality (VR) exercises in frail older adults to decrease the anxiety of falling and to induce improvements in behavioural and cognitive abilities in rehabilitation processes. …”
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    Enhancement of Anticipatory Postural Adjustments by Virtual Reality in Older Adults with Cognitive and Motor Deficits: A Randomised Trial
  7. 1927
    “…Clinical and prognostic differences between symptomatic and asymptomatic older patients with COVID-19 are of great interest since frail patients often show atypical presentation of illness. …”
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    Usefulness of lung ultrasound for selecting asymptomatic older patients with COVID 19 pneumonia
  8. 1928
    “…RESULTS: Sixty-two (17.2%) participants were frail, 199 (55.3%) pre-frail and 99 (27.5%) robust. …”
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    Frailty associations with socioeconomic status, healthcare utilisation and quality of life among older women residing in regional Australia
  9. 1929
    “…Therefore, to create supportive communities for frail older adults, appropriate measures have been taken to establish community centers within their walking distance. …”
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    Role of community centers in promoting sustainable regional life of community-dwelling older adults with frailty
  10. 1930
    “…Meta-analysis based on the random-effects model will be conducted to compare the outcomes between frail and non-frail patients. The evidential quality of the findings will be assessed with the GRADE profiler. …”
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    Influence of preoperative frailty on quality of life after cardiac surgery: Protocol for a systematic review and meta-analysis
  11. 1931
    “…At baseline, 79 patients (51 elderly and 28 middle-aged) were frail. The CVD frail patients showed functional dependency and a poor QoL compared to the non-frail (p < 0.001) and within each subgroup at follow-up. …”
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    Exploring the Relationship between Frailty, Functional Status, Polypharmacy, and Quality of Life in Elderly and Middle-Aged Patients with Cardiovascular Diseases: A One-Year Follow-Up Study
  12. 1932
    “…Compared to edentulousness, having teeth was associated with lower odds of cognitive impairment and higher odds of being robust or pre-frail. Denture-wearers compared with edentulous persons were less likely to be male, had higher education level and more likely be robust or pre-frail. …”
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    Association between dentition and frailty and cognitive function in community-dwelling older adults
  13. 1933
    “…Patients were divided into 3 groups (not frail, prefrail, and frail), and frailty was measured with the 5-item FRAIL scale. …”
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    Predictors associated with prefrailty in older Taiwanese individuals with type 2 diabetes
  14. 1934
    “…METHODS: A cross-sectional survey was conducted and participants were divided into three groups: non-frail group, pre-frail group, and frail group. Our sample included 100 individuals randomly selected from each group for the dietary survey. …”
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    Study on the Association Between Dietary Habits, Patterns and Frailty of the Elderly: A Cross-Sectional Survey from Communities in China
  15. 1935
    “…Half (49%) were confirmed as frail after CGA. All instruments differentiated frail from non-frail states, although the CFS (AUROC: 0.91) and PRISMA-7 (AUROC: 0.90) had higher accuracy compared to the VIP-4 (AUROC: 0.84) and VIP-3 (AUROC: 0.84). …”
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    Frailty Screening in the Emergency Department: Comparing the Variable Indicative of Placement Risk, Clinical Frailty Scale and PRISMA-7
  16. 1936
    “…The toxicities may offset the benefits of anti-myeloma therapy in frail patients. The accurate evaluation of frailty status before chemotherapy is essential. …”
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    Development and validation of a chemotherapy tolerance prediction model for Chinese multiple myeloma patients: The TM frailty score
  17. 1937
    “…Frail individuals had higher prospective and retrospective falling rates and higher 3-year mortality. …”
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    Relationships between orthostatic hypotension, frailty, falling and mortality in elderly care home residents
  18. 1938
    por Davenport, Andrew
    Publicado 2021
    “…The CFS is a useful screening tool that can be readily performed by dialysis staff to identify frail patients. Frailty in HD patients was associated with increasing age, comorbidity, fat weight and inflammation and reduced muscle strength and muscle mass. …”
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    Application of the Clinical Frailty Score and body composition and upper arm strength in haemodialysis patients
  19. 1939
    “…Exercise is effective in reducing falls for frail aging people (RaR, 0.75; 95% CI, 0.68–0.82) and participants with ND (0.53, 0.43–0.65) [dementia (0.64, 0.51–0.82), Parkinson’s disease (0.49, 0.39–0.69), and stroke survivors (0.40, 0.27–0.57)]. …”
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    Exercise for prevention of falls and fall-related injuries in neurodegenerative diseases and aging-related risk conditions: a meta-analysis
  20. 1940
    “…The frailty index (FI) based on 33 potential deficits was used to classify individuals as robust (FI < 0.12), pre-frail (FI ≧0.12 and <0.25) and frail (FI ≥0.25). …”
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    Prevalence and factors associated with frailty and pre-frailty in the older adults in China: a national cross-sectional study
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