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3861“…The parameters of such models—free energy differences for equilibrium properties and in general rates for equilibrium and out-of-equilibrium observables—have to be measured by different experiments or calculated from multiple computer simulations. …”
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3862“…However, there are still remaining challenges to overcome to elucidate the free energy scheme of laccase. Obtaining thermodynamic data on intermediates is hard or even impossible with analytical techniques. …”
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3863por de Moliner, Fabio, Konieczna, Zuzanna, Mendive‐Tapia, Lorena, Saleeb, Rebecca S., Morris, Katie, Gonzalez‐Vera, Juan Antonio, Kaizuka, Takeshi, Grant, Seth G. N., Horrocks, Mathew H., Vendrell, Marc“…Herein we have built a library of benzodiazole amino acids and systematically examined them as reporters for background‐free fluorescence microscopy. We have identified amine‐derivatized benzoselenadiazoles as scalable and photostable amino acids for the straightforward solid‐phase synthesis of fluorescent peptides. …”
Publicado 2022
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3864por Oldehinkel, Marianne, Tiego, Jeggan, Sabaroedin, Kristina, Chopra, Sidhant, Francey, Shona M., O’Donoghue, Brian, Cropley, Vanessa, Nelson, Barnaby, Graham, Jessica, Baldwin, Lara, Yuen, Hok Pan, Allott, Kelly, Alvarez-Jimenez, Mario, Harrigan, Susy, Pantelis, Christos, Wood, Stephen J., McGorry, Patrick, Bellgrove, Mark A., Fornito, Alex“…We applied connectopic mapping to resting-state fMRI data to obtain the first-order and second-order striatal connectivity modes in two distinct samples: (1) 56 antipsychotic-free patients (26 females) with first-episode psychosis (FEP) and 27 healthy controls (17 females); and (2) a community-based cohort of 377 healthy individuals (213 females) comprehensively assessed for subclinical PLEs and schizotypy. …”
Publicado 2023
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3865
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3866“…Using DNA staining dyes such as SYBR Green I (SGI) and thioflavin T (ThT) to perform label-free detection of aptamer binding has been performed for a long time for both binding assays and biosensor development. …”
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3867“…In human bipedal walking, the plantar surface of the foot is in contact with the floor surface, so that a vertical free moment (VFM), a torque about a vertical axis acting at the centre-of-pressure due to friction between the foot and the ground, is generated and applied to the foot. …”
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3868“…However, growing concerns about the environmental and health effects of perfluorinated compounds have caused increased interest in fluorine-free alternatives. Polydimethylsiloxane (PDMS) is most promising. …”
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3869“…Therefore, approaches to functionalizing existing C–H bonds of free phenols have continuously attracted the attention of organic chemists. …”
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3870por Blázquez-Martín, Agustín, Ruiz-Bardillo, Ainara, Verde-Sesto, Ester, Iturrospe, Amaia, Arbe, Arantxa, Pomposo, José A.“…We report herein on a new platform for synthesizing stable, inert, and dispersible metal-free single-chain nanoparticles (SCNPs) via intramolecular metal-traceless azide–alkyne click chemistry. …”
Publicado 2023
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3871por Banka, Alison L., Guevara, M. Valentina, Brannon, Emma R., Nguyen, Nhien Q., Song, Shuang, Cady, Gillian, Pinsky, David J., Uhrich, Kathryn E., Adili, Reheman, Holinstat, Michael, Eniola-Adefeso, Omolola“…Our data represent initial work in developing cargo-free, anti-platelet therapeutics specifically for conditions of thromboinflammation.…”
Publicado 2023
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3873“…The only treatment for celiac disease is lifelong adherence to a gluten-free diet (GFD), and the best way to achieve adherence is through education from a registered dietitian who has expertise in celiac disease. …”
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3874“…In this issue of Cell Reports Methods, LaLone et al. have shown that quantitative confocal Raman spectral imaging, a label-free technique, can reliably monitor organoid development, drug accumulation, and drug metabolism.…”
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3875por Roshandel, Hootan, Shammami, Matthew, Lin, Shiyun, Wong, Yin-Pok, Diaconescu, Paula L.Enlace del recurso
Publicado 2023
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3876por Rodríguez-Prados, Macarena, Berezhnaya, Elena, Castromonte, Maria Teresa, Menezes-Filho, Sergio L., Paillard, Melanie, Hajnóczky, György“…To overcome this barrier, we have studied the mtCU in divalent-free conditions by assessing the Ru265-sensitive Na(+) influx using fluorescence-based measurement of mitochondrial matrix [Na(+)] (free sodium concentration) rise and the ensuing depolarization and swelling. …”
Publicado 2023
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3877“…Floor egg-laying behavior (FELB) is one of the most concerning issues in commercial cage-free (CF) houses because floor eggs (i.e., mislaid eggs on the floor) result in high labor costs and food safety concerns. …”
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3878por Aspasia, Spyridaki, Emmanuela-Kalliopi, Kotsoni, Nikolaos, Thalassinos, Eirini, Sfakianaki, Ioannis, Sfendourakis, Anastasia, Markaki“…OBJECTIVE: The only available treatment for coeliac disease (CD) is a lifelong strict gluten-free diet (GFD), which can be extremely challenging. …”
Publicado 2022
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3879“…We addressed this question with repeated presentation of an array of coloured shapes followed by verbal free recall after delays of 1 day, 1 week, and 1 month. …”
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3880