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  1. 4621
    por Manzoni, Francesco, Ryde, Ulf
    Publicado 2018
    “…We have calculated relative binding affinities for eight tetrafluorophenyl-triazole-thiogalactoside inhibitors of galectin-3 with the alchemical free-energy perturbation approach. We obtain a mean absolute deviation from experimental estimates of only 2–3 kJ/mol and a correlation coefficient (R(2)) of 0.5–0.8 for seven relative affinities spanning a range of up to 11 kJ/mol. …”
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  2. 4622
    “…BACKGROUND: Free jejunal transfer (FJT) is a standard method of reconstruction after total pharyngo-laryngo-cervical esophagectomy (TPLE) in patients with advanced head and neck cancer. …”
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  3. 4623
    “…RESULTS: We found a statistically significant increase in free κ chains in both AChR- and MuSK-MG patients, while free λ chain levels were increased only in AChR-MG. …”
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  4. 4624
    “…Previous observations indicated seeding of denuded mesothelium by free-floating mesothelial cells may contribute to mesothelial healing. …”
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  5. 4625
  6. 4626
  7. 4627
    “…CONCLUSIONS: VAI was associated with hyperuricemia among individuals free of metabolic syndrome, and also a powerful indicator.…”
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  8. 4628
    “…This simple surfactant-free double miniemulsion polymerization technique opens a promising avenue for mass production of various complex hybrid nanostructures that are amenable to numerous applications.…”
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  9. 4629
    “…Objective  The anterior-lateral thigh (ALT) free flap is a flexible reconstructive option with fascia lata, fasciocutaneous, and musculocutaneous options. …”
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  10. 4630
  11. 4631
    “…We present a challenging case requiring staged reconstruction with two free latissimus dorsi flaps after the initial use of a medial gastrocnemius flap.…”
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  12. 4632
    “…Free-base meso-tetra(pentafluorophenyl)porphyrin, 1, is electrocatalytically active for hydrogen gas generation in the presence of p-toluenesulfonic acid. …”
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  13. 4633
  14. 4634
    “…A Rockwell indenter made of natural diamond was selected as the tool used, and the material of the workpiece was oxygen-free copper. Scratch topography was measured using a super-depth microscope to analyze the material deformation of the scratching process. …”
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  15. 4635
    “…CONCLUSIONS: Urban/rural and socioeconomic inequalities in C-section access did not change substantially after the countries implemented free C-section policies. User fee exemption is not enough. …”
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  16. 4636
    “…Here, we report the development of a Vibrio-based cell-free protein synthesis system (CFPS). Specifically, up to 0.4 g L(-1) eGFP could be successfully synthesized in small-scale batch reactions using cell-free extract obtained from fast-growing V. natriegens cultures. …”
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  17. 4637
    “…Fluorescence lifetime imaging microscopy (FLIM) of intrinsic fluorophores such as nicotinamide adenine dinucleotide (NADH) allows for label-free quantification of metabolic activity of individual cells over time and in response to various stimuli, which is not feasible using traditional methods due to their destructive nature and lack of spatial information. …”
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  18. 4638
    por Li, Jian, Zhang, Lingkai, Liu, Wanqiu
    Publicado 2018
    “…Then, we introduce the cell-free protein synthesis (CFPS)-based technology for natural product production. …”
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  19. 4639
    “…RESULTS: By general linear analysis, a significant linear trend between free triiodothyronine (FT3) and LDL-C level (linear coefficient r = –0.082, P = 0.001) and FT3 and total cholesterol (TC) level (r = –0.105, P = 0.031) was observed in the moderate-intensity statin group. …”
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  20. 4640
    “…Mitochondria play a key role in the pathophysiology of post-injury inflammation. Cell-free mitochondrial DNA (cf-mtDNA) is now understood to catalyse sterile inflammation after trauma. …”
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