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4801por Öster, Carl, Hendriks, Kitty, Kopec, Wojciech, Chevelkov, Veniamin, Shi, Chaowei, Michl, Dagmar, Lange, Sascha, Sun, Han, de Groot, Bert L., Lange, Adam“…Using solid-state nuclear magnetic resonance techniques tailored to characterize the interaction between water molecules and the ion channel, we show here that the selectivity filter of a potassium channel is free of water under physiological conditions. Our results are fully consistent with the direct knock-on mechanism of ion conduction but contradict the previously proposed water-mediated knock-on mechanism.…”
Publicado 2019
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4802por Choi, Yun-Seok, Bollinger, Sarah A., Prada, Luisa F., Scavone, Francesco, Yao, Tingting, Cohen, Robert E.“…The sensors bind specifically to free Ub, have K(d) values down to 60 pM, and, in concert with a newly developed workflow, allow us to distinguish and quantify the pools of free, protein-conjugated, and thioesterified forms of Ub from cell lysates. …”
Publicado 2019
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4803“…In addition, we propose a relaxation of the hard threshold in the connection probabilities, which opens up the possibility for obtaining sparse scale free networks with arbitrary scaling exponent.…”
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4804por Huang, Sheng, Chi, Yayun, Chi, Weiru, Guo, Rong, Su, Yonghui, Xue, Jingyan, Zhou, Shaoqiang, Wang, Jiankui, Yang, Zhuangqing, Nie, Jianyun, Shao, Zhimin, Chen, Dedian, Wu, Jiong“…RESULTS: LINC00309 high expression was an independent predictor for worse disease-free survival (HR = 2.127; 95% CI 1.074–4.212; p = 0.030) and associated with a shorter disease-free survival (p = 0.027), especially in hormone-positive breast cancer patients (p = 0.001). …”
Publicado 2019
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4805por Malik, Hafiz Abid Mahmood, Abid, Faiza, Mahmood, Nadeem, Wahiddin, Mohamed Ridza, Malik, Asif“…CONCLUSIONS: The results showed that the network topology exhibits the features of a scale-free network instead of a random network. Focal hubs are highlighted and the critical period is found. …”
Publicado 2019
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4806por Spagnolo, Anna Maria, Sartini, Marina, Di Cave, David, Casini, Beatrice, Tuvo, Benedetta, Cristina, Maria LuisaEnlace del recurso
Publicado 2019
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4807por Iamaguchi, Raquel Bernardelli, de Moraes, Marco Aurélio, Silva, Gustavo Bersani, Cho, Alvaro Baik, Iwase, Fernanda do Carmo, Wei, Teng Hsiang, de Rezende, Marcelo Rosa, Mattar, Rames“…The incidence of obesity is increasing and is associated with higher rates of free flap complications, which can lead to disastrous results. …”
Publicado 2019
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4808“…PURPOSE: In the last years, some studies investigated dosimetric benefits of a free flattening filter for the photon mode in the radiotherapy field. …”
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4809“…With the development of lead-free solders in electronic packaging, Sn-Cu lead-free solder has attracted wide attention due to its excellent comprehensive performance and low cost. …”
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4811por Hemmati, Saman Moritz, Ghadjar, Pirus, Grün, Arne, Badakhshi, Harun, Zschaeck, Sebastian, Senger, Carolin, Acker, Güliz, Misch, Martin, Budach, Volker, Kaul, David“…Primary endpoint was progression-free survival (PFS). RESULTS: This analysis included 99 patients with atypical meningioma (WHO grade II). …”
Publicado 2019
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4813“…This paper describes an integrative framework based on the behavioural literature to design better, equitable and ethically acceptable interventions for free-roaming cat management. ABSTRACT: In Australia, free-roaming cats can be found in urban and rural areas across the country. …”
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4814por Ofori, Edward, DeKosky, Steven T., Febo, Marcelo, Colon-Perez, Luis, Chakrabarty, Paramita, Duara, Ranjan, Adjouadi, Malek, Golde, Todd E., Vaillancourt, David E.“…In this paper, we test the hypothesis that free-water in the hippocampus will be more sensitive to early stages of cognitive decline than hippocampal volume, and that free-water in hippocampus will increase across distinct clinical stages of Alzheimer's disease. …”
Publicado 2019
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4815“…The only treatment currently available to combat celiac disease (CD) is strict adherence to a gluten-free diet (GFD), but there may be various determinants of its adherence, including food neophobia (FN), that is associated with sensory aversions, or fears of negative consequences of eating specific food products, that may be crucial for CD patients following a GFD. …”
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4816por Dubuc, Emilien, Pieters, Pascal A, van der Linden, Ardjan J, van Hest, Jan CM, Huck, Wilhelm TS, de Greef, Tom FA“…In this review, we discuss the uses of cell-free transcription–translation reactions for the development of synthetic genetic circuits, with a special focus on the use of microcompartments supporting this reaction. …”
Publicado 2019
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4817por Courtney, Eliza, Chok, Amanda Kay-Lyn, Ting Ang, Zoe Li, Shaw, Tarryn, Li, Shao-Tzu, Yuen, Jeanette, Ngeow, Joanne“…The aim of this study was to determine the impact of free cascade testing on uptake and identify other associated factors. …”
Publicado 2019
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4818“…The Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels were successfully synthesized using reversible addition-fragmentation chain-transfer (RAFT) and free radical polymerization (FRP). The gels were prepared while using different crosslinker feed and monomer concentration. …”
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4819por Titus, Andrea R., Kalousova, Lucie, Meza, Rafael, Levy, David T., Thrasher, James F., Elliott, Michael R., Lantz, Paula M., Fleischer, Nancy L.“…We examined area-based measures of exposure to smoke-free laws, as well as self-reported exposure to workplace smoke-free policies. …”
Publicado 2019
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4820por Wang, Guoying, Su, Ying, Yu, Jianglei, Li, Ruihong, Ma, Shangrong, Niu, Xiuli, Shi, Gaofeng“…The reaction capacity of three different membranes for free radicals are shown as follow, glycyrrhizin acid membrane > quercetin membrane > α-mangostin membrane. …”
Publicado 2019
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