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  1. 483981
    “…In the study, 22 patients had a diagnosis of sepsis with varying degrees of AKI, while the remaining 11 were free of sepsis. Statistical analysis demonstrated that in patients with septic AKI versus those without, the following were significantly higher: serum NGAL (447.5 ± 35.7 ng/mL vs. 256.5 ± 31.8 ng/mL, P value 0.001), calprotectin (1030.3 ± 298.6 pg/mL vs. 248.1 ± 210.7 pg/mL, P value 0.049), urinary NGAL (434.2 ± 31.5 ng/mL vs. 208.3 ± 39.5 ng/mL, P value < 0.001), and SOFA score (11.5 ± 1.2 vs. 4.4 ± 0.5, P value < 0.001). …”
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    A combination of SOFA score and biomarkers gives a better prediction of septic AKI and in-hospital mortality in critically ill surgical patients: a pilot study
  2. 483982
    “…Analysis of progression-free survival (PFS) and overall survival (OS) showed statistically significant improvement for patients treated with Nab-Pac + Gem versus Gem. …”
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    Paclitaxel as Albumin-Bound Nanoparticles with Gemcitabine for Untreated Metastatic Pancreatic Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
  3. 483983
    “…METHODS: We retrospectively identified 88 participants with 186 pairs of DENSE and balanced steady state free precession (bSSFP) image slices acquired at the same locations across two institutions. …”
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    Comparison of left ventricular strains and torsion derived from feature tracking and DENSE CMR
  4. 483984
    “…Secondary endpoints include progression-free and overall survival. DISCUSSION: If the multimodal PRIDE concept provides high predictive performance for pCR, the results of this study will play an important role in accurate identification of esophageal cancer patients with a pCR to nCRT. …”
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    Preoperative image-guided identification of response to neoadjuvant chemoradiotherapy in esophageal cancer (PRIDE): a multicenter observational study
  5. 483985
    “…Microdialysate corticosterone levels were reduced by NaHS in both LPS pretreated and untreated rats. The formation of free radicals in the hippocampus significantly reduced in LPS pretreated rats, while in LPS untreated rats a significant increase was observed after NaHS infusion. …”
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    Hydrogen Sulfide Affects Radical Formation in the Hippocampus of LPS Treated Rats and the Effect of Antipsychotics on Hydrogen Sulfide Forming Enzymes in Human Cell Lines
  6. 483986
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    Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015
  7. 483987
    “…While the app prompted re-engagement at set intervals, participants were free to complete each task as many times as they wished. …”
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    A Mobile App Delivering a Gamified Battery of Cognitive Tests Designed for Repeated Play (OU Brainwave): App Design and Cohort Study
  8. 483988
    “…Sixty CTEPH patients (mean age: 55 years ± 13 years; 25 males) and 30 normal controls (mean age: 54 years ± 14 years; 14 males) were enrolled in this study. RV free wall (RVFW) systolic peak longitudinal strain (LS) including the basal, mid-, and apical-segments and the basal longitudinal and transverse displacement (basal-DL and basal-DT) were measured by STE. …”
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    The value of speckle-tracking echocardiography in identifying right heart dysfunction in patients with chronic thromboembolic pulmonary hypertension
  9. 483989
    “…We previously observed that a free drug area under the curve to MIC ratio (fAUC/MIC) >27.43 was predictive of survival when DAP was administered as monotherapy. …”
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    1643. Pharmacodynamics (PD) of Daptomycin (DAP) in Combination Therapy for Enterococcal Bloodstream Infection (BSI)
  10. 483990
    “…Using the previously measured mouse plasma binding (>99.9%), the free AUC /MIC values for stasis and 1-log(10) kill ranged from 2.1–2.7 and 3.2–5.2, respectively. …”
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    1346. The Tetrazole VT-1598 Is Efficacious in a Murine Model of Invasive Aspergillosis with a PK/PD Expected of a Mold-Active CYP51 Inhibitor
  11. 483991
    “…Eligible trials compared zinc (ZN), vitamin A, micronutrients (MN), probiotics, prebiotics, symbiotics, racecadotril, smectite(SM), loperamide, diluted milk, lactose-free formula(LCF), or their combinations, to placebo or standard treatment (STND), or among them. …”
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    Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis
  12. 483992
    “…Currently approved HIV self-tests offer toll-free lines that are insufficient for initiating expedited linkages to counseling and care, accurate interpretation, and support during HIV self-testing. …”
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    An Unsupervised Smart App–Optimized HIV Self-Testing Program in Montreal, Canada: Cross-Sectional Study
  13. 483993
    “…At a median follow-up of 8 months, median progression-free survival was 15 months (95% CI, 11 to not estimable). …”
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    A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
  14. 483994
    “…Background: Different from males with Duchenne/Becker muscular dystrophy (DMD/BMD) in whom overt myopathy is the rule, muscular dystrophy (MD) female carriers are mostly free of skeletal muscle symptoms. However, similar to MD males, these females are also prone to cardiomyopathy. …”
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    Identification of Cardiomyopathy-Associated Circulating miRNA Biomarkers in Muscular Dystrophy Female Carriers Using a Complementary Cardiac Imaging and Plasma Profiling Approach
  15. 483995
    “…The platform was customized for a pediatric hemophilia population that required hands-free navigation to allow access to a child’s hands or arms for procedures. …”
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    A Novel Clinician-Orchestrated Virtual Reality Platform for Distraction During Pediatric Intravenous Procedures in Children With Hemophilia: Randomized Controlled Trial
  16. 483996
    “…In the overall population, the disease progression incidence rate was 0.57 [95% confidence interval (CI): 0.48–0.67] per person-year; median progression-free survival (PFS) was 22.4 (95% CI: 20.4–24.7) and overall survival (OS) was 45.0 (95% CI: 40.9–55.0) months. …”
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    Epidemiological characteristics, clinical outcomes and management patterns of metastatic breast cancer patients in routine clinical care settings of Greece: Results from the EMERGE multicenter retrospective chart review study
  17. 483997
    por Vidal, Roberto M., Muhsen, Khitam, Tennant, Sharon M., Svennerholm, Ann-Mari, Sow, Samba O., Sur, Dipika, Zaidi, Anita K. M., Faruque, Abu S. G., Saha, Debasish, Adegbola, Richard, Hossain, M. Jahangir, Alonso, Pedro L., Breiman, Robert F., Bassat, Quique, Tamboura, Boubou, Sanogo, Doh, Onwuchekwa, Uma, Manna, Byomkesh, Ramamurthy, Thandavarayan, Kanungo, Suman, Ahmed, Shahnawaz, Qureshi, Shahida, Quadri, Farheen, Hossain, Anowar, Das, Sumon K., Antonio, Martin, Mandomando, Inacio, Nhampossa, Tacilta, Acácio, Sozinho, Omore, Richard, Ochieng, John B., Oundo, Joseph O., Mintz, Eric D., O’Reilly, Ciara E., Berkeley, Lynette Y., Livio, Sofie, Panchalingam, Sandra, Nasrin, Dilruba, Farag, Tamer H., Wu, Yukun, Sommerfelt, Halvor, Robins-Browne, Roy M., Del Canto, Felipe, Hazen, Tracy H., Rasko, David A., Kotloff, Karen L., Nataro, James P., Levine, Myron M.
    Publicado 2019
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    Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS)
  18. 483998
    “…At final follow-up, 170 of 185 patients (92%) were pain free. For the 15 patients with persistent pain at final follow-up, no identifiable risk factors for persistent pain were identified. …”
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    Outcomes After the Operative Treatment of Bucket-Handle Meniscal Tears in Children and Adolescents
  19. 483999
    “…RESULTS: High CTSD mRNA levels correlated with shorter recurrence-free survival in TNBC, and extracellular cath-D was detected in the tumor microenvironment, but not in matched normal breast stroma. …”
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    Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies
  20. 484000
    “…Responses to CaCl(2) were assessed in arteries activated with phenylephrine (PE) and kept in Ca(2+)-free solution, in the absence and presence of the selective antagonist of L-type Ca(2+) channels nifedipine, cyclopiazonic acid (CPA) to block sarcoplasmic reticulum (SR) intracellular Ca(2+) release or specific inhibitors of PI3K, ERK-MAPK, or PKC. …”
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    Role of Phosphatidylinositol 3-Kinase (PI3K), Mitogen-Activated Protein Kinase (MAPK), and Protein Kinase C (PKC) in Calcium Signaling Pathways Linked to the α(1)-Adrenoceptor in Resistance Arteries
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