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484441por Haehl, Erik, Rühle, Alexander, Klink, Rabea, Kalckreuth, Tobias, Sprave, Tanja, Gkika, Eleni, Zamboglou, Constantinos, Meiß, Frank, Grosu, Anca-Ligia, Nicolay, Nils H.“…MATERIAL AND METHODS: In this retrospective single-center analysis, locoregional control (LRC), progression-free survival (PFS) and overall survival (OS) of elderly patients > 65 years with cSCC of the head-and-neck region undergoing radiotherapy between 2010 and 2019 were calculated. …”
Publicado 2021
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484442por Sun, Mingyu, Tang, Chuangang, Liu, Jun, Jiang, Wenli, Yu, Haifeng, Dong, Fang, Huang, Caiguo, Rixiati, Youlutuziayi“…High mRNA expression levels of SOCS2 (p < 0.001), SOCS3 (p < 0.001), and SOCS4 (p < 0.01), and a low expression level of SOCS5 (p < 0.001) were predicted to be significantly associated with better recurrence-free survival (RFS). Multivariate analysis showed that SOCS2 was an independent prognostic factor for RFS. …”
Publicado 2021
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484443por Alves-Ferreira, Miguel, Quintas, Marlene, Sequeiros, Jorge, Sousa, Alda, Pereira-Monteiro, José, Alonso, Isabel, Neto, João Luís, Lemos, Carolina“…METHODS: A case-control study was performed comprising 183 migraineurs (148 females and 35 males) and 265 migraine-free controls (202 females and 63 males). Tagging single nucleotide polymorphisms of NRXN2 were genotyped to assess the association between NRXN2 and migraine susceptibility. …”
Publicado 2021
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484444por Bustamante, Prisca, Tsering, Thupten, Coblentz, Jacqueline, Mastromonaco, Christina, Abdouh, Mohamed, Fonseca, Cristina, Proença, Rita P., Blanchard, Nadya, Dugé, Claude Laure, Andujar, Rafaella Atherino Schmidt, Youhnovska, Emma, Burnier, Miguel N., Callejo, Sonia A., Burnier, Julia V.“…METHODS: We used the highly sensitive digital droplet PCR (ddPCR) assay to quantify UM driver mutations (GNAQ, GNA11, PLCβ4 and CYSTLR2) in cell-free DNA (cfDNA). cfDNA was analyzed in six well established human UM cell lines with known mutational status. cfDNA was analyzed in the blood and aqueous humor of an UM rabbit model and in the blood of patients. …”
Publicado 2021
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484445por Artegoitia, Virginia M., Krishnan, Sridevi, Bonnel, Ellen L., Stephensen, Charles B., Keim, Nancy L., Newman, John W.“…METHODS: Diet patterns and quality were evaluated using 24 h recall-based Healthy Eating Index (HEI-2015) in free-living apparently healthy men (n = 184) and women (n = 209) 18–65 y of age with BMIs of 18–44 kg/m(2). …”
Publicado 2021
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484446por Horwich, P., MacKay, C., Bullock, M., Taylor, S. M., Hart, R., Trites, J., Geldenhuys, L., Williams, B., Rigby, M. H.“…One other patient with positive final margins received escalated therapy for additional negative prognostic factors. Recurrence free survival at 3 years was 88.4 and 50.7% for negative and positive final margins respectively (p = 0.048). …”
Publicado 2021
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484447por Gao, Jing-Wei, Hao, Qing-Yun, Gao, Ming, Zhang, Kun, Li, Xiong-Zhi, Wang, Jing-Feng, Vuitton, Dominique A., Zhang, Shao-Ling, Liu, Pin-Ming“…METHODS: We included 12,320 Atherosclerosis Risk in Communities Study participants (aged 54.3 ± 5.7 years) free of a history of PAD at baseline (visit 1: 1987–1989). …”
Publicado 2021
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484448High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcomepor Jamshidi, Maral, Fagerholm, Rainer, Muranen, Taru A., Kaur, Sippy, Potdar, Swapnil, Khan, Sofia, Netti, Eliisa, Mpindi, John-Patrick, Yadav, Bhagwan, Kiiski, Johanna I., Aittomäki, Kristiina, Heikkilä, Päivi, Saarela, Jani, Bützow, Ralf, Blomqvist, Carl, Nevanlinna, Heli“…We found that while high miR-30d expression is typical for aggressive tumors, it predicts better metastasis-free (p(BDDM) = 0.035, HR = 0.63, 95% CI = 0.4–0.9) and breast cancer-specific survival (p(BCS) = 0.018, HR = 0.61, 95% CI = 0.4–0.9), especially in HER2-positive (p(BDDM) = 0.0009), ER-negative (p(BDDM) = 0.003), p53-positive (p(BDDM) = 0.011), and highly proliferating (p(BDDM) = 0.0004) subgroups, and after adjuvant chemotherapy (p(BDDM) = 0.035). …”
Publicado 2021
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484449por Fehrenbach, Uli, Wuensch, Tilo, Gabriel, Pia, Segger, Laura, Yamaguchi, Takeru, Auer, Timo Alexander, Beetz, Nick Lasse, Denecke, Christian, Kröll, Dino, Raakow, Jonas, Knitter, Sebastian, Chopra, Sascha, Thuss-Patience, Peter, Pratschke, Johann, Hamm, Bernd, Biebl, Matthias, Geisel, Dominik“…These imaging biomarkers were correlated with major complications, anastomotic leakage, postoperative pneumonia, duration of postoperative hospitalization, disease-free survival (DFS), and overall survival (OS). Results: Preoperatively, sarcopenia was identified in 58 patients (68.2%), and sarcopenic obesity was present in 7 patients (8.2%). …”
Publicado 2021
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484450por Duerinck, Johnny, Schwarze, Julia Katharina, Awada, Gil, Tijtgat, Jens, Vaeyens, Freya, Bertels, Cleo, Geens, Wietse, Klein, Samuel, Seynaeve, Laura, Cras, Louise, D’Haene, Nicky, Michotte, Alex, Caljon, Ben, Salmon, Isabelle, Bruneau, Michaël, Kockx, Mark, Van Dooren, Sonia, Vanbinst, Anne-Marie, Everaert, Hendrik, Forsyth, Ramses, Neyns, Bart“…GB recurrence was diagnosed in 26 patients (median progression-free survival (PFS) is 11.7 weeks (range 2–152)); 21 patients have died due to progression. …”
Publicado 2021
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484451“…Menarcheal age was significantly and inversely associated with fat mass index (FMI) (β = − 0.080 cm, 95% CI (− 0.13, − 0.03), p = 0.002), but not with waist circumference and fat free mass index (FFMI) (p > 0.05). Birth weight SDS was positively and significantly associated with waist circumference (β = 0.035 cm, 95% CI (0.01, 0.06), p = 0.009), FMI (β = 0.087 cm, 95% CI (0.01, 0.16), p = 0.027), and FFMI (β = 0.485 cm, 95% CI (0.17, 0.80), p = 0.003). …”
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484452por Wang, Hongwu, Huang, Peng, Zhang, Ruibiao, Feng, Xueyong, Tang, Qiulin, Liu, Sixi, Wen, Feiqiu, Zeng, Li, Liu, Yufeng, Wang, Tianyou, Ma, Lian“…This study recruited 224 children (aged 3–6 years, exposed group) who lived in Guiyu and 204 children (aged 3–6 years, control group) who lived in a town free of e-waste pollution. Blood levels of lead, Hb, ferritin, folate and vitamin B(12) were tested in all children. …”
Publicado 2021
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484453“…BACKGROUND: Certification of seed potato as free of viruses is essential for stable potato production. …”
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484454por Stampini, Viviana, Monzani, Alice, Caristia, Silvia, Ferrante, Gianluigi, Gerbino, Martina, De Pedrini, Alberto, Amadori, Roberta, Rabbone, Ivana, Surico, Daniela“…Descriptive analysis was performed for both groups of participants, whereas a Poisson analysis was used to measure the association between some structural variables (age, education, socio-economic data, partner support, contact, free time, previous children, and pregnancy trimester) and anxiety or depression, difficulties in healthy eating and reduction in physical activity after lockdown started. …”
Publicado 2021
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484455“…RESULTS: Of the 336 cancer-free ADS enrolled in the Clinical Breast Care Project, 77 had a family history that met National Comprehensive Cancer Network criteria for genetic testing for BRCA1/2 and 2 had a family history of colon cancer meeting the criteria for genetic testing for Lynch syndrome. …”
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484456“…We aimed to compare worldwide government responses to the spread of COVID-19, to examine the relationship between response level, response timing and the epidemic trajectory. METHODS: Free publicly-accessible data collected by the Coronavirus Government Response Tracker (OxCGRT) were used. …”
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484457por Iwanami, Shoya, Ejima, Keisuke, Kim, Kwang Su, Noshita, Koji, Fujita, Yasuhisa, Miyazaki, Taiga, Kohno, Shigeru, Miyazaki, Yoshitsugu, Morimoto, Shimpei, Nakaoka, Shinji, Koizumi, Yoshiki, Asai, Yusuke, Aihara, Kazuyuki, Watashi, Koichi, Thompson, Robin N., Shibuya, Kenji, Fujiu, Katsuhito, Perelson, Alan S., Iwami, Shingo, Wakita, TakajiEnlace del recurso
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484458por Gao, Guoying, Zhou, Chengzhi, Huang, Yucheng, Hong, Ziying, Yu, Pei, Chen, Ying, Gao, Jiabo, Zhang, Kening, Xie, Zhanhong, Zhang, Jiexia, Li, Shiyue, Masashi, Nagata, Qin, Yinyin“…The primary endpoints were progression-free survival (PFS), and overall survival (OS). RESULTS: Among the 52 patients (DC, n=25; GC, n=27), the median follow-up time was 12.3 months. …”
Publicado 2021
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484459por Terzolo, Massimo, Fassnacht, Martin, Perotti, Paola, Libe, Rossella, Lacroix, André, Kastelan, Darko, Haak, Harm Reinout, Arlt, Wiebke, Loli, Paola, Decoudier, Bénédicte, Lasolle, Helene, Bancos, Irina, Quinkler, Marcus, Villares Fragoso, Maria Candida Barisson, Canu, Letizia, Puglisi, Soraya, Kroiss, Matthias, Dusek, Tina, Bourdeau, Isabelle, Baudin, Eric, Berchialla, Paola, Beuschlein, Felix, Bertherat, Jerome Yves, Berruti, Alfredo“…The randomized controlled study ADIUVO compared the efficacy of adjuvant mitotane treatment vs. observation in prolonging recurrence-free survival (RFS) in ACC patients at low-intermediate risk of recurrence. …”
Publicado 2021
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484460por Martín, Nerea Itza, Fresno, Luis Salamanca, Palma, Cristina Mora, Marcos, Miguel Saenz De Pipaon, Casado, Isabel Gonzalez, Barros, Angel Campos“…Newborns older than 7 days of age, with diagnostic criteria of hyperinsulinism: non ketotic hypoglycemia with detectable insulin, low free fatty acids, glucose infusion rate > 10mg/kg/min, and positive response to glucagon test, were recruited. …”
Publicado 2021
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