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  1. 484581
    “…Eligible studies also involved positive psychology interventions designed to enhance physician well-being or reduce physician burnout. Using free text and the medical subject headings we searched CINAHL, Ovid PsychINFO, MEDLINE, and Google Scholar (GS) electronic bibliographic databases from 2000 until March 2020. …”
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    Contribution of a positive psychology-based conceptual framework in reducing physician burnout and improving well-being: a systematic review
  2. 484582
    “…BACKGROUND: The ImPrEP México demonstration project is the first to distribute free HIV pre-exposure prophylaxis (PrEP) to men who have sex with men (MSM) and transgender women living in Mexico. …”
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    Barriers and facilitators to pre-exposure prophylaxis uptake among male sex workers in Mexico: an application of the RE-AIM framework
  3. 484583
    “…Strength was assessed by knee extensor 1-RM and isokinetic dynamometry ∼ every 10 d. Thigh fat free mass (TFFM) was measured by DXA at 0/3/6 weeks. …”
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    Omega-3 supplementation during unilateral resistance exercise training in older women: A within subject and double-blind placebo-controlled trial
  4. 484584
    “…The endpoints of progression-free survival (PFS) and overall response rate (ORR) were analyzed in the two groups, and the overall response [partial response (PR), stable disease (SD), and progressive disease (PD)] of each patient was determined using RECIST 1.1 evaluation criteria. …”
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    Activity of PD-1 Inhibitor Combined With Anti-Angiogenic Therapy in Advanced Sarcoma: A Single-Center Retrospective Analysis
  5. 484585
    “…METHODS: This is a prospective analysis of 492,479 participants free of stroke from the UK biobank. Incident stroke was identified through linkage to hospital admission and death registries using the International Classification of Diseases (ICD)-10 codes (I60, I61, I63, and I64). …”
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    Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials
  6. 484586
    “…At 12 months, 169 (16.4%) patients were seizure-free and 383 (37.2%) were seizure responders. The rate of seizure freedom was 22.3% in LEV-naive patients, 7.1% in patients with prior LEV use and discontinuation due to insufficient efficacy, and 31.2% in patients with prior LEV use and discontinuation due to AEs (p < 0.001); the corresponding values for ≥ 50% seizure frequency reduction were 47.9%, 29.7%, and 42.8% (p < 0.001). …”
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    Adjunctive Brivaracetam in Focal Epilepsy: Real-World Evidence from the BRIVAracetam add-on First Italian netwoRk STudy (BRIVAFIRST)
  7. 484587
    “…To investigate this finding in a free-living context, we aimed to examine associations of device-measured 24-h time-use compositions of sitting, standing, stepping, and sleeping with fasting glucose (FPG) and 2 h post-load glucose (2hPLG) levels, and to examine separately the associations with time-use compositions among those at lower and at higher risk of developing type 2 diabetes. …”
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    Contrasting compositions of sitting, standing, stepping, and sleeping time: associations with glycaemic outcome by diabetes risk
  8. 484588
    “…BACKGROUND: The invasive and complicated procedures involving the use of traditional stem cells limit their application in bone tissue engineering. Cell-free, tissue-engineered bones often have complex scaffold structures and are usually engineered using several growth factors (GFs), thus leading to costly and difficult preparations. …”
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    Graphene oxide-modified silk fibroin/nanohydroxyapatite scaffold loaded with urine-derived stem cells for immunomodulation and bone regeneration
  9. 484589
    “…METHODS: In a prospective, cross-sectional, monocentric study, 100 pain-free asymptomatic women, aged 20–64 years were enrolled. …”
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    Evaluation of 3D vertebral and pelvic position by surface topography in asymptomatic females: presentation of normative reference data
  10. 484590
    “…Fixed drug concentrations were the human plasma-free adjusted clinical trough concentrations (C(min)) or fixed at simulated C(min) after missing 1 to 4 consecutive doses (C(min)-1 to -4), with many replicates. …”
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    888. In Vitro Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence
  11. 484591
    “…Final MAP Bayesian parameter estimates were used to simulate free time above MIC (%ƒT >MIC) for various cefepime dosing regimens. …”
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    1109. Pharmacokinetics and Exposure of Cefepime in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)
  12. 484592
    “…Novel, independent predictors of ASB treatment included behavioral issues, such as falls or fatigue (odds ratio (OR): 1.8; 95% CI: 1.05-3.07), urine characteristics, such as cloudy or odorous urine (OR: 1.41; 95% CI: 1.13-1.75), voiding issues (OR: 1.86; 95% CI: 1.43-2.41), and a single, free text mention of a SIRS criteria (OR: 1.63; 95% CI: 1.16-2.3). …”
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    73. Identification of Novel Factors Associated with Inappropriate Treatment of Asymptomatic Bacteriuria Treatment in Acute and Long-term Care
  13. 484593
    “…Adverse Effects [Image: see text] CONCLUSION: Patients on IV TMP-SMX therapy were more likely to experience an ADE compared to PO, likely driven by the high volume of free water. Most patients on IV TMP-SMX were on other PO medications, suggesting a missed stewardship opportunity for IV to PO conversion to reduce patient harm. …”
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    56. High Frequencies of Adverse Drug Events with Intravenous vs Oral High-Dose Trimethoprim-Sulfamethoxazole: An Opportunity for Antibiotic Stewardship
  14. 484594
    “…Treatment resulted in reduction in fasting levels of triglycerides by 59.9 %, ANGPTL3 by 54.7 %, and in several other lipoproteins/lipids, including very low-density lipoprotein cholesterol by 53.5 %, non-high-density lipoprotein cholesterol by 20.9 %, and free fatty acids (FFA) by 41.7 %. The area under the curve for postprandial triglycerides, FFA, and glucose was reduced by 60 %, 32 %, and 14 %, respectively. …”
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    Selective targeting of angiopoietin-like 3 (ANGPTL3) with vupanorsen for the treatment of patients with familial partial lipodystrophy (FPLD): results of a proof-of-concept study
  15. 484595
    “…Plasma concentration of fluazuron at second and third application was increased (3.3 and 2.9 times, respectively) in calves under free suckling compared to cows. Nevertheless, both groups of cows and calves showed a significant increase in plasma concentration of fluazuron between times (4.9 times, p < 0.0001 and 2.8 times, p < 0.0001, respectively). …”
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    Is the suckling period and application pattern relevant for fluazuron against tick infestation in cows and their suckling calves?
  16. 484596
    por Tombak, Anıl, Pepedil Tanrıkulu, Funda, Durusoy, Salih Sertaç, Dinçyürek, Hüseyin Derya, Kaya, Emin, Ümit, Elif Gülsüm, Yavaşoğlu, İrfan, Mehtap, Özgür, Deveci, Burak, Özcan, Mehmet Ali, Terzi, Hatice, Okay, Müfide, Sayınalp, Nilgün, Yılmaz, Mehmet, Okan, Vahap, Kızıklı, Alperen, Özcan, Ömer, Çetin, Güven, Demircioğlu, Sinan, Aydoğdu, İsmet, Saydam, Güray, Davulcu, Eren Arslan, İlhan, Gül, Uçar, Mehmet Ali, Özet, Gülsüm, Akpınar, Seval, Turgut, Burhan, Berber, İlhami, Kurtoğlu, Erdal, Sönmez, Mehmet, Batur, Derya Selim, Yıldırım, Rahşan, Özkocamaz, Vildan, Güneş, Ahmet Kürşad, Sahip, Birsen, Ertop, Şehmus, Akay, Olga Meltem, Baştürk, Abdülkadir, Doğu, Mehmet Hilmi, Akdeniz, Aydan, Ünal, Ali, Seyhanlı, Ahmet, Gürkan, Emel, Çekdemir, Demet, Ferhanoğlu, Burhan
    Publicado 2021
    “…Treatment response, survival outcome including overall survival (OS) and progression-free survival (PFS), and safety data were analyzed. …”
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    Efficacy and Safety of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia: Retrospective Analysis of Real-Life Data
  17. 484597
    “…Assisted self-collection of specimens and barrier free communication may facilitate implementation in homeless shelters. …”
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    Monitoring for COVID-19 by universal testing in a homeless shelter in Germany: a prospective feasibility cohort study
  18. 484598
    “…Patients had comparable concentrations of growth hormone, insulin-like growth factor-I (IGF-I) and IGF-binding protein 1 (IGFBP1), but higher IGFBP3 (p = 0.030) than controls. Total and free cortisol, cortisol-binding globulin and albumin concentrations were comparable for patients and controls. …”
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    Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness
  19. 484599
    por Tao, Yali, Zhou, Hui, Niu, Ting
    Publicado 2021
    “…Outcome measures of efficacy included overall response rate (ORR), clinical benefit rate (CBR), stringent complete response rate (sCR), complete response rate (CR), very good partial response (VGPR), partial response rate (PR), minimal response (MR), rate of stable disease (SDR), rate of progressive disease (PDR) and median progression-free survival (mPFS). Safety was evaluated by the incidences of all grade adverse events and Grade≥3 adverse events. …”
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    Safety and Efficacy Analysis of Selinexor-Based Treatment in Multiple Myeloma, a Meta-Analysis Based on Prospective Clinical Trials
  20. 484600
    “…MAIN OUTCOMES AND MEASURES: The primary end point was investigator-assessed progression-free survival (PFS). Secondary end points included overall survival, objective response rate (ORR), disease control rate (DCR), duration of response, time to objective response, and safety. …”
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    Apatinib vs Placebo in Patients With Locally Advanced or Metastatic, Radioactive Iodine–Refractory Differentiated Thyroid Cancer: The REALITY Randomized Clinical Trial
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