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484701por Buregyeya, Esther, Atusingwize, Edwinah, Sekandi, Juliet N., Mugambe, Richard, Nuwematsiko, Rebecca, Atuyambe, Lynn“…Facilitators were; physical capability (availability of free TB services in the public health facilities), social opportunity (availability of translators). …”
Publicado 2022
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484702“…A meta-analysis was performed to generate combined hazard ratio (HR) with 95% confidence intervals (CI) for disease-free survival (DFS), overall survival (OS), and risk ratio (RR) with 95% CI for disease recurrence and adverse events (AEs). …”
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484703por Lai, Tsai-Chun, Chen, Yu-Chen, Cheng, Hui-Hua, Lee, Tzu-Lin, Tsai, Jaw-Shiun, Lee, I.-Ta, Peng, Kuo-Ti, Lee, Chiang-Wen, Hsu, Lee-Fen, Chen, Yuh-Lien“…In addition, PM significantly increased the production of reactive oxygen species (ROS) in HUVECs and mitochondria treated with HG and decreased the expression of superoxide dismutase 1 (SOD1), a free radical scavenging enzyme. The coexposure group exhibited significantly increased ROS production in cells and mitochondria, a lower mitochondrial membrane potential, and increased levels of the autophagy-related proteins p62, microtubule-associated protein 1 light chain 3β (LC3B), and mitophagy-related protein BCL2 interacting protein 3 (Bnip3). …”
Publicado 2022
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484704“…Gene expression levels were compared between uninfected tomato plants (i.e., controls and plants infested with Lso-free psyllids) and infected plants (i.e., plants infested with psyllids infected with either Lso haplotype A or Lso haplotype B). …”
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484705por Li, Sheng-Tang, Zhang, Tao, Shi, Xue-Wen, Liu, Hua, Yang, Cheng-Wei, Zhen, Ping, Li, Song-Kai“…The fragment can move in upward, inferior, and lateral directions, which often causes low back pain and discomfort, abnormal sensation, and movement of lower limbs. The free disc fragments detached from the parent disc often mimic spinal tumors. …”
Publicado 2022
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484706por Pearson, Nicole, Finch, Meghan, Sutherland, Rachel, Kingsland, Melanie, Wolfenden, Luke, Wedesweiler, Taya, Herrmann, Vanessa, Yoong, Sze Lin“…The primary outcomes were kilojoules from discretionary foods and associated nutrients (saturated fat, free sugars, and sodium) packed in children’s lunch boxes. …”
Publicado 2022
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484707por Jones, Robin L., Ravi, Vinod, Brohl, Andrew S., Chawla, Sant, Ganjoo, Kristen N., Italiano, Antoine, Attia, Steven, Burgess, Melissa A., Thornton, Katherine, Cranmer, Lee D., Cheang, Maggie Chon U., Liu, Lingyun, Robertson, Liz, Adams, Bonne, Theuer, Charles, Maki, Robert G.“…Carotuximab plus pazopanib produced a median progression-free survival (PFS) of 7.8 months in pazopanib-naive patients with chemotherapy-refractory angiosarcoma in a phase 1/2 trial. …”
Publicado 2022
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484708por Karamzad, Nahid, Faraji, Esmaeil, Adeli, Shaghayegh, Sullman, Mark J. M., Pourghassem Gargari, Bahram“…The body composition indices (i.e., body fat percentage, fat mass, fat free mass, muscle mass, bone mass and total body water) were not significantly different between groups or across the trial. …”
Publicado 2022
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484709por Zerella, Maria Alessia, Zaffaroni, Mattia, Ronci, Giuseppe, Dicuonzo, Samantha, Rojas, Damaris Patricia, Morra, Anna, Fodor, Cristiana, Rondi, Elena, Vigorito, Sabrina, Botta, Francesca, Cremonesi, Marta, Garibaldi, Cristina, Penco, Silvia, Galimberti, Viviana Enrica, Intra, Mattia, Gandini, Sara, Barberis, Massimo, Renne, Giuseppe, Cattani, Federica, Veronesi, Paolo, Orecchia, Roberto, Jereczek-Fossa, Barbara Alicja, Leonardi, Maria Cristina“…Moreover, patients with oligometastatic disease synchronous with primary BC may benefit from APBI on the intact tumor in terms of tumor progression free survival. The study of response to RT can provide useful information about BC radiobiology, immunologic reactions, genomic expression, and radiomics features, to be tested on a larger scale. …”
Publicado 2022
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484710por Anderson, Lindsey J., Lee, Jonathan, Anderson, Barbara, Lee, Benjamin, Migula, Dorota, Sauer, Adam, Chong, Nicole, Liu, Haiming, Wu, Peter C., Dash, Atreya, Li, Yi‐Ping, Garcia, Jose M.“…There was no difference across groups in absolute REE (P = 0.061), %predicted REE (P = 0.18), circulating free fatty acids (FFA, P = 0.13) or parathyroid hormone‐related peptide (PTHrP; P = 0.88), or WAT protein expression of inflammation (IL‐6, P = 0.51; IL‐1β, P = 0.29; monocyte chemoattractant protein‐1, P = 0.23) or WAT protein or gene expression of browning (uncoupling protein‐1, UCP‐1; P = 0.13, UCP‐1, P = 0.14). …”
Publicado 2022
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484711por Liu, Xue-Feng, Zhu, Xiao-Dong, Feng, Long-Hai, Li, Xiao-Long, Xu, Bin, Li, Kang-Shuai, Xiao, Nan, Lei, Ming, Sun, Hui-Chuan, Tang, Zhao-You“…Secondary outcomes included objective response rate (ORR) and progression-free survival (PFS). A subcutaneous syngeneic HCC model was generated in C57BL/6 mice. …”
Publicado 2022
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484712“…METHODS: Four experimental DP surfactant formulations consisting of 70% of phospholipids (DPPC:POPG 7:3), 3% Super Mini-B (SMB) or its sulfur-free derivate B-YL as SP-B peptide mimic, 25% of lactose or trehalose as excipient, and 2% of NaCl were formulated using spray drying. …”
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484713por Tang, Zhaoqing, Wang, Yan, Yu, Yiyi, Cui, Yuehong, Liang, Liang, Xu, Chen, Shen, Zhenbin, Shen, Kuntang, Wang, Xuefei, Liu, Tianshu, Sun, Yihong“…At the data cutoff date (September 30, 2021), the median event-free survival was 42.6 (95% CI, 16.2 to not reached) months, and the median overall survival was not reached. …”
Publicado 2022
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484714por Jaworski, Beth K, Taylor, Katherine, Ramsey, Kelly M, Heinz, Adrienne J, Steinmetz, Sarah, Owen, Jason E, Tsai, Jack, Pietrzak, Robert H“…However, overall comfort with mobile devices and factors influencing the uptake and usage of mobile apps during the pandemic among older veterans are not well known. COVID Coach is a free, evidence-informed mobile app designed for pandemic-related stress. …”
Publicado 2022
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484715“…Finally, ROC analysis showed a significant advancement when introducing ePWV into established risk factors (0.787 vs. 0.810, p for comparison < 0.001), and reclassification analysis also confirmed significant improvement from ePWV to identify LVH prevalence (category-free net reclassification analysis = 0.421, p < 0.001; integrated discrimination index = 0.023, p < 0.001). …”
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484716por Beltrán-Camacho, Lucía, Eslava-Alcón, Sara, Rojas-Torres, Marta, Sánchez-Morillo, Daniel, Martinez-Nicolás, Mª Pilar, Martín-Bermejo, Victoria, de la Torre, Inés García, Berrocoso, Esther, Moreno, Juan Antonio, Moreno-Luna, Rafael, Durán-Ruiz, Mª Carmen“…Healthy CACs were incubated ex-vivo with the serum of either COVID-19 negative (PCR −/IgG −, n:8) or COVID-19 positive asymptomatic donors, at different infective stages: PCR +/IgG − (n:8) and PCR −/IgG + (n:8). Also, a label free quantitative approach was applied to identify and quantify protein differences between these serums. …”
Publicado 2022
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484717por Poteska, Renata, Rahbar, Kambiz, Semjonow, Axel, Schrader, Andres Jan, Boegemann, Martin, Schlack, Katrin“…RESULTS: In Kaplan-Meier analysis, ALP rising at 12 weeks with or without LDH-normalization was associated with significantly worse median progression-free survival (PFS) of 3 months vs. 5 months (Log rank P = 0.02) and 3 months vs. 5 months (P = 0.01), respectively and overall survival (OS) with 8 months vs. 15 months (P = 0.02) and 8 months vs. 17 months (P < 0.01). …”
Publicado 2022
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484718por König, Frederik, Grossmann, Nico C., Soria, Francesco, D’Andrea, David, Juvet, Tristan, Potretzke, Aaron, Djaladat, Hooman, Ghoreifi, Alireza, Kikuchi, Eiji, Hayakawa, Nozomi, Mari, Andrea, Khene, Zine-Eddine, Fujita, Kazutoshi, Raman, Jay D., Breda, Alberto, Fontana, Matteo, Sfakianos, John P., Pfail, John L., Laukhtina, Ekaterina, Rajwa, Pawel, Pallauf, Maximilian, Cacciamani, Giovanni E., van Doeveren, Thomas, Boormans, Joost L., Antonelli, Alessandro, Jamil, Marcus, Abdollah, Firas, Budzyn, Jeffrey, Ploussard, Guillaume, Heidenreich, Axel, Daneshmand, Siamak, Boorjian, Stephen A., Rouprêt, Morgan, Rink, Michael, Shariat, Shahrokh F., Pradere, Benjamin“…On multivariable analyses, achieving the pentafecta was associated with improved recurrence-free survival (RFS), CSS, and OS. No preoperative clinical factors predicted a failure to validate the pentafecta. …”
Publicado 2022
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484719por Riviere, Aaron J., Smith, Kristen S., Schaberg, Megan N., Greene, Michael W., Frugé, Andrew D.“…Lack of concordance between several inflammation-associated biomarkers and zonulin corroborate recent reports of limited utility of zonulin in obese adults free of lower gastrointestinal disease. Trial Registration information: https://clinicaltrials.gov/ct2/show/NCT03582306 (NCT03582306) registered on 07/11/2018. …”
Publicado 2022
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484720por Jin, Jia, Ji, Dongmei, Xia, Zuguang, Xue, Kai, Zhang, Qunling, Liu, Yizhen, Cao, Junning, Hong, Xiaonan, Gu, Juan J., Guo, Ye, Lv, Fangfang“…The primary endpoint was 3-year progression-free survival (PFS). Overall survival (OS) in this study was compared with those from a historical study (NCT 00854568159). …”
Publicado 2022
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