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485041por Xu, Bichun, Zhao, Xianzhi, Chen, Di, Zhao, Wenjuan, Wang, Xiaoyan, Ding, Changhua, Yuan, Zhiyong, Zhang, Huojun“…The effectiveness was assessed based on local control (LC), progression-free survival (PFS), and overall survival (OS), which were calculated using the Kaplan-Meier method. …”
Publicado 2023
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485042por Wang, Lingquan, Ni, Zhentian, Xu, Wei, Mei, Yu, Li, Chen, Zhu, Zhenggang, Liu, Wentao“…The Kaplan–Meier method was used to estimate the disease-free survival (DFS) and overall survival (OS) of the whole group. …”
Publicado 2023
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485043por Kanters, Steve, Ball, Graeme, Kahl, Brad, Wiesinger, Adriana, Limbrick-Oldfield, Eve H., Sudhindra, Akshay, Snider, Julia Thornton, Patel, Anik R.“…Kaplan-Meier (KM) curves for progression-free survival (PFS) and overall survival (OS) estimated by reconstructing digitized curves using the Guyot algorithm, and survival analyses were conducted, stratified by ≥2 prior LOT and ≥ 3 prior LOT groups (as defined in the source material). …”
Publicado 2023
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485044“…Key barriers: time and financial constraints, lack of free cessation medications and follow-up, deprioritisation and unclear targets in primary care, lack of knowledge of healthcare professionals, and unclear messaging to patients about available cessation support options. …”
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485045por Ávila, Mario I., Vajda, Élodie A., Jeffrey Gutiérrez, Eileen, Gibson, Daragh, Renteria, Mariela Mosquera, Presley, Nicolas, O’Reilly, Daniel, Tatarsky, Allison, Lobo, Neil F.“…BACKGROUND: Although most of Panamá is free from malaria, localized foci of transmission persist, including in the Guna Yala region. …”
Publicado 2023
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485046por Prickett, Timothy C R, Pearson, John F, Troughton, Richard W, Kennedy, Martin A, Espiner, Eric A“…METHODS: All of the 348 participants (205/348, 58.9% female; 53/348, 15.2% Māori or Pacifica ethnicity) participating in the original CHALICE study—free of history of heart or renal disease at age 50 years and who consented to further study—will be contacted, recruited, and restudied as previously described. …”
Publicado 2023
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485047por McGee-Vincent, Pearl, Mackintosh, Margaret-Anne, Jamison, Andrea L, Juhasz, Katherine, Becket-Davenport, Colleen, Bosch, Jeane, Avery, Timothy J, Glamb, Lauren, Hampole, Shilpa“…BACKGROUND: The National Center for PTSD, within the Department of Veterans Affairs (VA), has developed a suite of free, publicly available, evidence-informed apps that can reach an increasing number of veterans and bridge gaps in care by providing resources to those who are not engaged in mental health treatment. …”
Publicado 2023
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485048por Ainsworth, Hannah, Marshman, Zoe, Whiteside, Katie, Sykes, Debbie, Fairhurst, Caroline, Turner, Emma, Chestnutt, Ivor, Day, Peter, Dey, Donna, Elliott, Louise, El-Yousfi, Sarab, Hewitt, Catherine, Jones, Claire, Pavitt, Sue, Robertson, Mark, Torgerson, David, Innes, Nicola“…Participants were pupils aged 11–13 years (in year 7/S1 or year 8/S2) in secondary schools in England, Scotland, and Wales with above average pupil eligibility for free school meals. Following completion of pupil baseline questionnaires and dental assessments, year groups within schools were randomised to the intervention or control arm. …”
Publicado 2023
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485049por Jake Shortt, Galettis, Peter, Cheah, Chan Y., Davis, Joanne, Ludford-Menting, Mandy, Link, Emma K., Martin, Jennifer H., Koldej, Rachel, Ritchie, David“…Hence, the MTD was not defined. Median progression-free and overall survival were 57 (range 29–539) days and 33 (95% CI 9.7– > 44) months, respectively. …”
Publicado 2023
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485050por Davies, Caitlin R., Guo, Tianyu, Burke, Edwina, Stankiewicz, Elzbieta, Xu, Lei, Mao, Xueying, Scandura, Glenda, Rajan, Prabhakar, Tipples, Karen, Alifrangis, Constantine, Wimalasingham, Akhila Ganeshi, Galazi, Myria, Crusz, Shanthini, Powles, Thomas, Grey, Alistair, Oliver, Tim, Kudahetti, Sakunthala, Shaw, Greg, Berney, Daniel, Shamash, Jonathan, Lu, Yong-Jie“…OBJECTIVE: In this study we investigate the potential of using CTCs and their gene expression to predict post-docetaxel tumour response, OS and progression free survival (PFS). METHODS: Peripheral blood was sampled from 18 mCRPC and 43 mHSPC patients, pre-docetaxel treatment, for CTC investigation. …”
Publicado 2023
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485051por Cluesman, Sabrina R., Gwadz, Marya, Freeman, Robin, Collins, Linda M., Cleland, Charles M., Wilton, Leo, Hawkins, Robert L., Leonard, Noelle R., Silverman, Elizabeth, Maslow, Carey B., Israel, Khadija, Ritchie, Amanda, Ory, Sarah“…Across components, a non-judgmental and pressure-free approach and attention to structural and cultural factors were seen as vital to high levels of engagement, but lacking in most medical/social service settings. …”
Publicado 2023
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485052por Lin, Yu-Jia, Chang, Hsiao-Ting, Lin, Ming-Hwai, Chen, Ru-Yih, Chen, Ping-Jen, Lin, Wen-Yuan, Hsieh, Jyh-Gang, Wang, Ying-Wei, Hu, Chung-Chieh, Liou, Yi-Sheng, Chiu, Tai-Yuan, Tu, Chun-Yi, Cheng, Bo-Ren, Chen, Tzeng-Ji, Chen, Fang-Pey, Hwang, Shinn-Jang“…Medical professionals should establish a friendly and barrier-free communication model, encourage patients to share CAM experiences, and provide evidence-based information on the use of CAM products and services, to reduce the potential damage caused by harmful use.…”
Publicado 2023
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485053por Cheng, Daoan, Zhao, Weiqing, Chen, Rui, Li, Dong, Tang, Shuxian, Fang, Cheng, Ji, Mei“…The primary endpoints were pathological tumor response (PTR) and event-free survival (EFS). The different clinic-pathological features were compared by the Kruskal-Wallis test for continuous variables and the Chi-square (χ(2)) test for categorical variables. …”
Publicado 2023
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485054por Brunklaus, Andreas, Feng, Tony, Brünger, Tobias, Perez-Palma, Eduardo, Heyne, Henrike, Matthews, Emma, Semsarian, Christopher, Symonds, Joseph D, Zuberi, Sameer M, Lal, Dennis, Schorge, Stephanie“…We integrated our findings into a free online webtool to facilitate functional sodium channel gene variant interpretation (http://SCN-viewer.broadinstitute.org).…”
Publicado 2022
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485055por Bricker, Jonathan, Miao, Zhen, Mull, Kristin, Santiago-Torres, Margarita, Vock, David M“…We also examined whether 13 baseline variables that included a variety of demographics (eg, race and ethnicity, gender, and age) and smoking characteristics (eg, use of e-cigarettes and confidence in being smoke free) might improve this prediction. RESULTS: The AUC for each logistic regression model using only the first 7 days of log-in count variables was 0.94 (95% CI 0.90-0.97) for iCanQuit, 0.88 (95% CI 0.83-0.93) for QuitGuide, 0.85 (95% CI 0.80-0.88) for WebQuit.org, and 0.60 (95% CI 0.54-0.66) for Smokefree.gov. …”
Publicado 2023
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485056por Cui, Chuanliang, Chen, Yu, Luo, Zhiguo, Zou, Zhengyun, Jiang, Yu, Pan, Hongming, Fan, Qingxia, Zhao, Jianfu, Xu, Qing, Jiang, Renbing, Wang, Xuan, Ma, Taiyang, Guo, Zhen, Si, Lu, Chi, Zhihong, Sheng, Xinan, Dou, Yiwei, Tan, Qian, Wu, Di, Guo, Jun“…The secondary endpoints were disease control rate (DCR), duration of response (DOR), progression-free survival (PFS), overall survival (OS), and toxicity. …”
Publicado 2023
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485057por Liu, Zijing, Xu, Tiankai, Chang, Pengyu, Fu, Weijia, Wei, Jiaying, Xia, Chengcheng, Wang, Qiang, Li, Man, Pu, Xiaoyu, Huang, Fuxue, Ge, Chao, Gao, Yan, Gong, Shouliang, Liu, Chengjiang, Dong, Lihua“…The primary outcomes were progression-free survival (PFS) and overall survival (OS), and the secondary outcomes were abscopal response rate (ARR), abscopal control rate (ACR), adverse events rate, and pneumonia rate. …”
Publicado 2023
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485058por Xu, Chong-Rui, Chen, Qixun, Zhou, Chengzhi, Wu, Lin, Li, Wen, Zhang, Huizhong, Li, Yongsheng, Xu, Fei, Xiong, Jianping, Wang, Qiming, Zhang, Haibo, Jiang, Yuequan, Yin, Haitao, Wu, Qingchen, Dai, Qiangsheng, Hu, Jian, Chen, Jianhua, Zhang, Jian, Wu, Gang, Yin, Jun, Zhao, Jianfu, Liu, Baogang, Shan, Jianzhen, Sheng, Liming, Chen, Qunqing, Han, Zhengxiang, Shi, Huaqiu, Liu, Yimin, Chen, Jun, Wu, Yi-Long“…The primary outcome was the objective response rate (ORR) and secondary outcomes were disease control rate (DCR), 6-month progression-free survival (PFS), overall survival (OS), and treatment-related adverse events (TRAEs). …”
Publicado 2023
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485059por Tomlins, Scott A., Khazanov, Nickolay A., Bulen, Benjamin J., Hovelson, Daniel H., Shreve, Melissa J., Lamb, Laura E., Matrana, Marc R., Burkard, Mark E., Yang, Eddy Shih-Hsin, Edenfield, William Jeffery, Dees, E. Claire, Onitilo, Adedayo A., Thompson, Michael, Buchschacher, Gary L., Miller, Alan M., Menter, Alexander, Parsons, Benjamin, Wassenaar, Timothy, Hwang, Leon C., Suga, J. Marie, Siegel, Robert, Irvin, William, Nair, Suresh, Slim, Jennifer N., Misleh, Jamal, Khatri, Jamil, Masters, Gregory, Thomas, Sachdev, Safa, Malek, Anderson, Daniel M., Kwiatkowski, Kat, Mitchell, Khalis, Hu-Seliger, Tina, Drewery, Stephanie, Fischer, Andrew, Plouffe, Komal, Czuprenski, Eric, Hipp, Jennifer, Reeder, Travis, Vakil, Hana, Johnson, D. Bryan, Rhodes, Daniel R.“…IRS real-world progression free survival (rwPFS) and overall survival (OS) prediction was validated in an independent cohort of trial patients. …”
Publicado 2023
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485060por Hou, Xue, Li, Meichen, Wu, Guowu, Feng, Weineng, Su, Jin, Jiang, Honghua, Jiang, Guanming, Chen, Jing, Zhang, Baishen, You, Zhixuan, Liu, Qing, Chen, Likun“…Several studies have shown that adding chemotherapy to EGFR-TKIs could improve progression-free survival (PFS) in patients with EGFR-mutant advanced NSCLC; however, the efficacy of these agents in patients with brain metastases remains unclear. …”
Publicado 2023
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