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485081por Roux, Damien, Benichou, Nicolas, Hajage, David, Martin-Lefèvre, Laurent, de Prost, Nicolas, Lerolle, Nicolas, Titeca-Beauport, Dimitri, Boulet, Eric, Mayaux, Julien, Mégarbane, Bruno, Mahjoub, Khaoula, Carpentier, Dorothée, Nseir, Saad, Tubach, Florence, Ricard, Jean-Damien, Dreyfuss, Didier, Gaudry, Stéphane“…Evolution of procalcitonin level and catecholamine-free days as well as mortality did not differ whether beta-lactam trough concentration was above 4 times the MIC or not. …”
Publicado 2023
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485082por Gu, Yixin, Han, Jian, Wang, Wenjie, Zhan, Yu, Wang, Huijie, Hua, Wenyuan, Liu, Yue, Guo, Yafeng, Xue, Zhuang, Wang, Wei“…The juvenile H. otakii-fed dietary CNE had lower triglycerides (TG) and total cholesterol (TCHO) levels in the serum than fish-fed CNE-free diets (P < 0.05). The gene expression of peroxisome proliferator-activated receptor alpha (PPAR-α), hormone-sensitive lipase (HSL), and carnitine O-palmitoyltransferase 1 (CPT1) in the liver was significantly increased by including CNE in fish diets regardless of the inclusion level (P < 0.05). …”
Publicado 2022
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485083por Kaira, Kyoichi, Yamaguchi, Ou, Naruse, Ichiro, Umeda, Yukihiro, Honda, Takeshi, Watanabe, Satoshi, Ichikawa, Kosuke, Yanagisawa, Shin, Kasahara, Norimitsu, Higuchi, Tetsuya, Hashimoto, Kosuke, Miura, Yu, Shiono, Ayako, Mouri, Atsuto, Imai, Hisao, Iizuka, Kunihiko, Ishizuka, Tamotsu, Minato, Koichi, Suda, Satoshi, Kagamu, Hiroshi, Mori, Keita, Seki, Nobuhiko, Kuji, Ichiei“…To distinguish controlled from uncontrolled disease, RECIST, irRECIST, and PET criteria (PERCIST, iPERCIST, and EORTC) defined by MTV or TLG were found to be significant predictors of progression-free survival. To distinguish responders from non-responders, iPERCIST by SUL(peak) or EORTC by TLG were identified as significant indicators. …”
Publicado 2023
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485084por Kjeld, Simone G., Thygesen, Lau C., Danielsen, Dina, Jakobsen, Gitte S., Jensen, Marie P., Holmberg, Teresa, Bast, Lotus S., Lund, Lisbeth, Pisinger, Charlotta, Andersen, Susan“…The intervention program comprised smoke-free school hours, class-based activities, and access to smoking cessation support. …”
Publicado 2023
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485085por Shi, Yuankai, Qin, Xintian, Peng, Xingchen, Zeng, Aiping, Li, Jingao, Chen, Chuanben, Qiu, Sufang, Pan, Suming, Zheng, Yulong, Cai, Jing, Chen, Xiaopin, Qu, Shenhong, Lin, Lizhu, Huang, Jianli, Wu, Hui, Lu, Ying, Wang, Wei, Hu, Changlu, He, Xia, Yu, Zhonghua, Liu, Xiaojian, Xie, Bo, Liu, Anwen, Hu, Guangyuan, Jing, Shanghua, Zhang, Qingyuan, Guo, Renhua, Li, Qi, Hong, Jinsheng, Jin, Feng, Meng, Juan, Shi, Jianhua, Wang, Peiguo, Cui, Jiuwei, Yang, Kunyu, Zhang, Xuebang, Li, Xiaojiang, Shen, Liangfang, He, Yuxiang, Zhai, Limin, Sun, Xiuhua, Ge, Junyou, Qing, Yan, Zong, Dekang“…For FAS population, the IRC-assessed ORR was 26.5% (95%CI 19.2–34.9%), and disease control rate (DCR) was 56.8% (95%CI 47.9–65.4%). Median progression-free survival (PFS) was 2.8 months (95%CI 1.5–4.1) . …”
Publicado 2022
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485086por Saranaruk, Paksiree, Waraasawapati, Sakda, Chamgramol, Yaovalux, Sawanyawisuth, Kanlayanee, Paungpan, Natnicha, Somphud, Narumon, Wongkham, Chaisiri, Okada, Seiji, Wongkham, Sopit, Vaeteewoottacharn, Kulthida“…RESULTS: GEPIA analysis indicated GM-CSF and GM-CSFRα expressions were higher in CCA tissues than in normal counterparts, and high GM-CSFRα was related to the longer disease-free survival of the patients (p < 0.001). IHC analysis revealed that CCA cells differentially expressed GM-CSF, while GM-CSFRα was expressed on cancer-infiltrating immune cells. …”
Publicado 2023
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485087por Yoshida, Soichiro, Takahara, Taro, Arita, Yuki, Ito, Masaya, Hayakawa, Sara, Oguchi, Tomohiko, Komai, Yoshinobu, Numao, Noboru, Yuasa, Takeshi, Inoue, Masaharu, Ushijima, Hiroki, Kudo, Shigehiro, Shimano, Yasumasa, Nakamura, Yuki, Uchida, Yusuke, Uehara, Sho, Tanaka, Hajime, Yaegashi, Hiroshi, Izumi, Kouji, Yokoyama, Minato, Matsuoka, Yoh, Yoshioka, Yasuo, Konishi, Koji, Nakanishi, Katsuyuki, Nagahara, Akira, Hirakawa, Akihiro, Koike, Ryuji, Koga, Fumitaka, Nishimura, Kazuo, Mizokami, Atsushi, Yonese, Junji, Kageyama, Yukio, Yoshimura, Ryoichi, Fujii, Yasuhisa“…The primary endpoint will be radiological progression-free survival against progression of bone metastases on WB-DWI. …”
Publicado 2023
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485088por Song, Shanshan, Han, Dongmei, Zhang, Ning, Mao, Zhuang, Guo, Xin, Cheng, Guanghui“…Clinical outcomes including overall survival (OS), cancer specific survival (CSS), progression free survival (PFS), local control (LC) were analyzed. …”
Publicado 2023
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485089“…The IFX doses at week 52 varied greatly according to age at diagnosis The median number of IFX blood level dosage was 4 per patient over a year (IQR=3-5).At week 52, 83 patients (84.6%) achieved clinical remission with a median IFX level of 10.96 (7.05-15.59). 74 /83 (89%) were on monotherapy and 9/83(10.8%) on combotherapy IMAGE: [Image: see text] CONCLUSION(S): Early treatment for IBD with IFX as monotherapy and an early proactive optimization strategy is associated with a good sustained steroid free clinical remissionAt week 52, 83 patients (84.6%) achieved clinical remission with a median IFX level of 10.96 (7.05-15.59). 74 /83 (89%) were on monotherapy and 9/83(10.8%) on combotherapy.The majority of the patients required IFX optimization during their first year of treatment. …”
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485090por Li, Yong, Zhou, Aiping, Liu, Shuoyan, He, Ming, Chen, Keneng, Tian, Ziqiang, Li, Yin, Qin, Jianjun, Wang, Zhen, Chen, Haiquan, Tian, Hui, Yu, Yue, Qu, Wang, Xue, Liyan, He, Shun, Wang, Shuhang, Bie, Fenglong, Bai, Guangyu, Zhou, Bolun, Yang, Zhaoyang, Huang, Huiyao, Fang, Yan, Li, Benjamin, Dai, Xiangrong, Gao, Shugeng, He, Jie“…The primary endpoint was major pathological response (MPR), and the secondary endpoints were pathological complete response (pCR), R0 resection rate, event-free survival (EFS), overall survival (OS), and safety. …”
Publicado 2023
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485091por Shiragannavar, Varsha D., Sannappa Gowda, Nirmala G., Puttahanumantharayappa, Lakshana D., Karunakara, Shreyas H., Bhat, Smitha, Prasad, Shashanka K., Kumar, Divya P., Santhekadur, Prasanna K.“…In vitro: Steatosis was induced in HepG2 and Huh7 cells using free fatty acids [Sodium Palmitate (SP) and Oleate (OA)]. …”
Publicado 2023
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485092por Endo, Makoto, Kataoka, Tomoko, Fujiwara, Toshifumi, Tsukushi, Satoshi, Takahashi, Masanobu, Kobayashi, Eisuke, Yamada, Yoko, Tanaka, Takaaki, Nezu, Yutaka, Hiraga, Hiroaki, Wasa, Junji, Nagano, Akihito, Nakano, Kenji, Nakayama, Robert, Hamada, Tetsuya, Kawano, Masanori, Torigoe, Tomoaki, Sakamoto, Akio, Asanuma, Kunihiro, Morii, Takeshi, Machida, Ryunosuke, Sekino, Yuta, Fukuda, Haruhiko, Oda, Yoshinao, Ozaki, Toshifumi, Tanaka, Kazuhiro“…The primary endpoint is progression-free survival, and the secondary endpoints include overall survival, disease-control rate, response rate, and adverse events. …”
Publicado 2023
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485093por Savona, Michael R., McCloskey, James K, Griffiths, Elizabeth A., Yee, Karen, Zeidan, Amer M., Al-Kali, Aref, Deeg, H. Joachim, Patel, Prapti, Sabloff, Mitchell, Keating, Mary-Margaret, Dao, Kim-Hien, Zhu, Nancy, Gabrail, Nashat, Fazal, Salman, Maly, Joseph, Odenike, Olatoyosi, Kantarjian, Hagop, DeZern, Amy E., O'Connell, Casey L., Roboz, Gail J., Busque, Lambert, Wells, Richard A., Amin, Harshad, Randhawa, Jasleen K., Leber, Brian, Hao, Yong, Keer, Harold N., Azab, Mohammad, Garcia-Manero, Guillermo“…Of six patients with baseline RBC transfusion dependence 3 (50%) became transfusion independent. Leukemia-free survival was 28.2 months and after a median follow up of more than 33 months, median overall survival had not been reached. …”
Publicado 2021
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485094por Garcia-Manero, Guillermo, McCloskey, James K, Griffiths, Elizabeth A., Yee, Karen, Zeidan, Amer M., Al-Kali, Aref, Deeg, H. Joachim, Patel, Prapti, Sabloff, Mitchell, Keating, Mary-Margaret, Dao, Kim-Hien, Zhu, Nancy, Gabrail, Nashat Y., Fazal, Salman, Maly, Joseph, Odenike, Olatoyosi, Kantarjian, Hagop, DeZern, Amy E., O'Connell, Casey L., Roboz, Gail J., Busque, Lambert, Wells, Richard A., Amin, Harshad, Randhawa, Jasleen K., Leber, Brian, Hao, Yong, Keer, Harold N., Azab, Mohammad, Savona, Michael R.“…With approximately 32 months of median follow up, neither median leukemia-free survival (mLFS) nor mOS had been reached (Figure 1). …”
Publicado 2021
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485095por Fraser, Alan, 1955-Tabla de Contenidos: “…Physical legato is the foundation of piano technique -- 11. A capable hand can free your arm -- pt. IV. Hand strength and function B : the special role of the thumb and its relationship to the forefinger -- 12. …”
Publicado 2003
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485096por Ghys, Lars Herman L“…This systematic trend, described with only two free parameters, was confirmed for experimental $\beta$DF partial half-lives spanning over seven orders of magnitude. …”
Publicado 2015
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485097por Porobic, Tomica“…The apparatus is situated at CERN/ISOLDE laboratory and consists of a unique combination of a retardation spectrometer and two Penning traps, with one of them serving as a scattering-free source. This configuration is suited for a precise measurement of the energy spectrum of 35Ar recoiled daughter ions. …”
Publicado 2017
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485098por Caliva, Alberto“…This is made of deconfined quasi-free quarks and gluons. Based on the current cosmological picture, the quark-gluon plasma was the state of our universe few $\mu$s after the Big Bang. …”
Publicado 2018
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485099“…Finally, the appendix contains a short description of some of the tools described in the book that are available from IIASA, free of charge, for research and educational purposes. …”
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485100por Kundu, Sourav“…QCD predicts that at a high temperature and/or density, the nuclear matter will make a transition to a strongly interacting matter in which quarks and gluons are free to move, and not confined as in hadrons. Such an extreme state of matter is known as quark-gluon plasma (QGP) which existed in the early stages of the Universe after the Big Bang. …”
Publicado 2021
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