“…In these animals the hemorrhagic areas were not infrequently 2 to 5 mm. in extent, and when occurring on the surface of the organ produced a separation of the capsule. Occasionally free blood was noted in the pelvis, and in the absence of hemorrhage within the pelvic lining, we assumed that it came from the uriniferous orifices of the calicos. …”
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“…As a reducing agent, at least 0.6 gm. per tube is required for the establishment of an adequate oxygen-free zone. 3. Culture media may be classified as reducing or non-reducing. …”
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“…It was found that without the addition of electrolyte the cataphoretic P.D. between particles and water is very minute near the point of neutrality (pH 5.8), often less than 10 millivolts, if care is taken that the solutions are free from impurities. Particles which in the absence of salts have a positive charge in water near the point of neutrality (pH 5.8) are termed positive colloids and particles which have a negative charge under these conditions are termed negative colloids. 2. …”
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“…It is labile and breaks down readily to yield coproporphyrin and the copper compound of coproporphyrin, and is apparently the source of the coproporphyrin which is often found free in the culture filtrates. In the work repeated earlier we had been unable to obtain this complex porphyrin, or porphyrin compound, directly from the bacteria. …”
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“…The question as to how much of the inhibitory power of plasma can be accounted for by the contained cholesterol (total or free) is one which can be answered only if the experimental conditions are defined with respect to initial concentration of lysin, time of contact, and several other variables. …”
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“…This latter is, in turn, determined by the innate tendency of the bacilli to return to an average of infectivity and by mouse individuals of greater resistance to restrict free growth and multiplication. In this manner, possibly, the epidemic spread is checked and the curve representing it made to fall more or less quickly to a base-line.…”
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“…Its form is obtainable at t(L) = 0.90 free from the influence of summating "cone" contributions, because then almost no overlapping occurs. …”
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“…The median progression-free survival and overall survival were 11.6 ± 0.4 and 18.1 ± 3.6 months respectively. …”
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“…Cardiotoxicity is the main dose-limiting side effect of doxorubicin in the clinic. Being a free radical producer, doxorubicin affects the heart specifically because of its low antioxidant capacity. …”
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“…However, quality of life data provided scientific evidence for clinical decision-making and conveyed helpful information concerning breast cancer patients' experiences during the course of the disease diagnosis, treatment, disease-free survival time, and recurrences; otherwise finding patient-centered solutions for evidence-based selection of optimal treatments, psychosocial interventions, patient-physician communications, allocation of resources, and indicating research priorities were impossible. …”
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“…The mechanisms of prevention and reversal of cataracts with NAC ophthalmic drug are considered which include prevention by the intraocular released carnosine of free-radical-induced inactivation of proprietary lens antioxidant enzymes (superoxide dismutase); prevention of carbohydrate and metal-catalyzed autooxidation of ascorbic acid-induced cross-linking glycation reactions to the lens proteins; transglycation properties of carnosine, allowing it to compete for the glycating agent, protecting proteins (lens crystallins) against modification; universal antioxidant and scavenging activity towards lipid hydroperoxides, aldehydes and oxygen radicals; activation with l-carnosine ingredient of proteasome activity in the lens; chaperone-like disaggregating to lens crystallins activity of NAC and of its bioactivated principal carnosine. …”
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“…The study end points were the proportion of patients achieving a 50% PSA response, progression-free survival (PFS), overall survival, and quality of life. …”
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“…Secondary outcomes were proportion of patients healed by 12 months, percentage and absolute change in ulcer size, proportion of time participants were ulcer-free, health related quality of life, and adverse events. …”
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