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485581por Haddad, Lisa B., Swaims-Kohlmeier, Alison, Mehta, C. Christina, Haaland, Richard E., Brown, Nakita L., Sheth, Anandi N., Chien, Hsin, Titanji, Kehmia, Achilles, Sharon L., Lupo, Davis, Hart, Clyde E., Ofotokun, IghoEnlace del recurso
Publicado 2020
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485582por Kumar, Gayathri S., Pezzi, Clelia, Wien, Simone, Mamo, Blain, Scott, Kevin, Payton, Colleen, Urban, Kailey, Hughes, Stephen, Kennedy, Lori, Cabanting, Nuny, Montour, Jessica, Titus, Melissa, Aguirre, Jenny, Kawasaki, Breanna, Ford, Rebecca, Jentes, Emily S.Enlace del recurso
Publicado 2020
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485583por Feldstein, Leora R., Bennett, Sarah D., Estivariz, Concepcion F., Cooley, Gretchen M., Weil, Lauren, Billah, Mallick Masum, Uzzaman, M. Salim, Bohara, Rajendra, Vandenent, Maya, Adhikari, Jucy Merina, Leidman, Eva, Hasan, Mainul, Akhtar, Saifuddin, Hasman, Andreas, Conklin, Laura, Ehlman, Daniel, Alamgir, A., Flora, Meerjady SabrinaEnlace del recurso
Publicado 2020
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485584Publicado 2020“…The 3- and 5-year overall survival (OS) rates of LELC patients were 87.5% and 50.0%, disease-free survival (DFS) rates were 87.5% and 50.0%, respectively. …”
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485585por Chen, Jia-Liang, Zhou, Xin, Liu, Bo-Long, Wei, Xu-Hong, Ding, Hong-Lu, Lin, Zhi-Jun, Zhan, Hai-Lun, Yang, Fei, Li, Wen-Biao, Xie, Jun-Cong, Su, Min-Zhi, Liu, Xian-Guo, Zhou, Xiang-Fu“…Western blot and immunofluorescence staining measured the expression of tumor necrosis factor-α/nuclear factor-κB (TNF-α/NF-κB), interleukin-1β (IL-1β), and N-methyl-d-aspartate receptor type 2B subunit (NR2B) of the N-methyl-d-aspartate receptor in the L6–S1 spinal dorsal horn (SDH) and hippocampus. RESULTS: Free Mg(2+) was reduced in the serum and CSF of the CYP-induced cystitis rats on days 8, 12, and 20 after the first CYP injection. …”
Publicado 2020
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485586por Bulteau, Samuel, Laurin, Andrew, Volteau, Christelle, Dert, Cécile, Lagalice, Lydie, Schirr-Bonnans, Solène, Bukowski, Nicolas, Guitteny, Marie, Simons, Luc, Cabelguen, Clémence, Pichot, Anne, Tessier, Fabienne, Bonnin, Annabelle, Lepage, Adeline, Vanelle, Jean-Marie, Sauvaget, Anne, Riche, Valery-Pierre“…The following criteria will be compared between arm A or B and arm C: rates of responders; remission and disease-free survival; clinical evolution; tolerance; observance; treatment modifications; hospitalization; suicide attempts; work stoppage; marital / professional statues; and quality of life at 12 and 24 months. …”
Publicado 2020
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485587por Chen, Shaojun, Hua, Li, Feng, Chengjun, Mo, Qia, Wei, Mengzhuan, Shen, Yongqi, Lin, Zhan, Li, Guisheng, Xu, Junyi, Guo, Chengxian, Huang, Haixin“…After chemotherapy with FOLFIRI, there was no significant difference in response rate (RR) (p = 0.729; p = 0.745) or in median progression-free survival (mPFS) between the wild-type, mutant treatment of UGT1A1*28 and UGT1A1*6 (7.0 m vs 7.4 m, p = 0.427; 6.9 m vs 7.0 m p = 0.408). …”
Publicado 2020
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485588por Weisser, Burkhard, Predel, Hans-Georg, Gillessen, Anton, Hacke, Claudia, vor dem Esche, Johannes, Rippin, Gerd, Noetel, Andrea, Randerath, Olaf“…AIM: We conducted a meta-analysis to compare the effect of SPC with that of free-combination treatment (FCT) in patients with either hypertension, dyslipidemia or the combination of both diseases under conditions of daily practice. …”
Publicado 2020
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485589por Chen, Wei, Liang, Jing-Lin, Zhou, Kai, Zeng, Qing-Li, Ye, Jun-Wen, Huang, Mei-Jin“…It can be used as an independent prognostic indicator to determine overall survival (OS) and disease-free survival (DFS). Depletion of CIP2A substantially suppressed the growth of CRC cells and colony formation in vitro, and inhibited the growth of xenograft tumors in vivo. …”
Publicado 2020
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485590por Cai, Ming-Ci, Cheng, Shu, Wang, Xin, Hu, Jian-Da, Song, Yong-Ping, Huang, Yao-Hui, Yan, Zi-Xun, Jiang, Yu-Jie, Fang, Xiao-Sheng, Zheng, Xiao-Yun, Dong, Li-Hua, Ji, Meng-Meng, Wang, Li, Xu, Peng-Peng, Zhao, Wei-Li“…There was no difference in median progression-free survival (PFS; 15.4 months vs. 9.2 months, p = 0.122) or overall survival (OS; 24.3 months vs. 21.9 months, p = 0.178). …”
Publicado 2020
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485591por Zhao, Houli, Wei, Jieping, Wei, Guoqing, Luo, Yi, Shi, Jimin, Cui, Qu, Zhao, Mingfeng, Liang, Aibin, Zhang, Qing, Yang, Jianmin, Li, Xin, Chen, Jing, Song, Xianmin, Jing, Hongmei, Li, Yuhua, Hao, Siguo, Wu, Wenjun, Tan, Yamin, Yu, Jian, Zhao, Yanmin, Lai, Xiaoyu, Yin, Elaine Tan Su, Wei, Yunxiong, Li, Ping, Huang, Jing, Wang, Tao, Blaise, Didier, Xiao, Lei, Chang, Alex H., Nagler, Arnon, Mohty, Mohamad, Huang, He, Hu, Yongxian“…RESULTS: Compared with the non-transplant group, transplantation recipients had a higher 2-year overall survival (OS; 77.0% versus 36.4%; P < 0.001) and leukemia-free survival (LFS; 65.6% versus 32.8%; P < 0.001). …”
Publicado 2020
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485592por Ozmen, Vahit, Ilgun, Serkan, Celet Ozden, Burcu, Ozturk, Alper, Aktepe, Fatma, Agacayak, Filiz, Elbuken, Filiz, Alco, Gul, Ordu, Cetin, Erdogan Iyigun, Zeynep, Emre, Hocaoglu, Pilancı, Kezban, Soybir, Gursel, Ozmen, Tolga“…There were no differences identified between the groups in terms of tumor histology, hormonal receptors and HER-2 positivity, surgical morbidity, and 5-year overall and disease-free survival. Group 2 patients were significantly younger than group 1 (p = 0.003). …”
Publicado 2020
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485593por Fighera, Tayane Muniz, da Silva, Eliane Dias, Borba, Gustavo da Silva, Spritzer, Poli Mara“…No difference was observed regarding estradiol levels between the groups [105.7pmol/L (48.4-207.8) and 147.5 pmol/L (71.9-284.5), p=0.622]. Free androgen index (FAI) was significantly higher [0.45 (0.17 - 1.63) and 4.47 (0.70 - 36.4), p=0.002] and FSH significantly lower [60.4mIU/ml (37.9 - 75.6) and 2.6mIU/ml (0.6 - 4.4), p=0.000] in trans women CAS - N. …”
Publicado 2020
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485594por Antonio, Leen, Dejaeger, Marian, Wu, Frederick C, O’Neill, Terence, Pye, Stephen, Huhtaniemi, Ilpo T, Rastrelli, Giulia, Forti, Gianni, Casanueva, Felipe F, Slowikowska-Hilczer, Jolanta, Punab, Margus, Vanderschueren, Dirk M, Tournoy, Jos“…While TT declines with age, free T (FT) shows a greater fall, due to the rise in SHBG. …”
Publicado 2020
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485595por Thakur, Shilpa, Daley, Brianna, Jacobson, Orit, Wang, Zhantong, Chen, Xiaoyuan, Klubo-Gwiezdzinska, Joanna“…Consequently, the progression-free survival (PFS) was significantly longer in (177)Lu-EB-TATE group (24±0 days) compared with (177)Lu-DOTA-TATE (7.7±2.6 days, p<0.001) and (177)Lu-DOTA-JR11 (6.3±3 days, p<0.001). …”
Publicado 2020
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485596“…Further laboratory evaluation revealed ACTH 9 pg/mL (ref 6-50), Random Cortisol 16.1 at 1:36pm, TSH 1.40uIU/ml, Free T4 1.09 ng/dL, Cosyntropin stimulation test at baseline 15.4 ug/dL; at 30 min 22 ug/dL; at 60 min 28.3 ug/dL and Beta-Hydroxybutyrate 0.11 mmol/L. …”
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485597“…Labs showed a low phosphorus at 2.1 mg/dL [2.7–4.5], along with calcium 8.8 mg/dL [8.4–10.4], iPTH 48 pg/mL [12–88], and ALP of 155 [IU]/L [34–104]. 25-OH vitamin D and 1,25-(OH)(2) vitamin D were 27 ng/mL [30–80] and 12 pg/mL [20–80], respectively. Free testosterone was 4.4 ng/mL [5–21] and LH 2.2 mIU/mL [3.0–10.0]. …”
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485598“…Total testosterone 68 ng/dL (2–45), free testosterone 7 pg/mL (0.1 - 6.4), FSH 5.7 mIU/mL (2.5–10.2), LH 10.6 mIU/mL (1.9–12.5), Progesterone 2.1 ng/mL (<1), Estradiol 51 pg/mL (19–144), 17-OH Progesterone 6728 ng/dL (45–285), Androstenedione 710 ng/dL (35–250), DHEA 1216 ng/dL (102 - 1185), 11-Deoxycortisol 204 ng/dL (<107), Pregnenolone 661 ng/dL(22–237), DHEAS 435 ng/dL (18–391). …”
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485599por Mohan, Dipika R, Finco, Isabella, LaPensee, Christopher Ryan, Rege, Juilee, Else, Tobias, Almeida, Madson Q, Vinco, Michelle, Wakamatsu, Alda, Latronico, Ana Claudia, Mendonca, Berenice Bilharinho, Zerbini, Maria Claudia N, Fragoso, Maria Candida Barisson Villares, Rainey, William E, Venneti, Sriram, Marie, Suely K N, Giordano, Thomas J, Lerario, Antonio Marcondes, Hammer, Gary D“…In embryonic stem cells, the Polycomb repressive complex 2 (PRC2) represses differentiation programs through EZH2-mediated histone H3 lysine 27 trimethylation (H3K27me3) deposition in promoter CpG islands free of DNA methylation. Gain or loss of EZH2/PRC2 function prevails in a variety of human cancers, enabling proliferation in a tissue-specific manner. …”
Publicado 2020
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485600“…Lab investigation revealed elevated PRL 73 ng/mL (n [normal] = 1-24), Total T3 305 ng/dL (n = 71-180), Free T4 (FT4) 2.37 ng/dL (n = 0.6-1.15), TSH 6.09 UIU/mL (n = 0.5-5.0), and α subunit 7.7 ng/mL. …”
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