“…BEAs most commonly involved the pituitary-adrenal axis [ACTH (N: 5-46 pg/mL): 6/21 (28.5%, 5 high, 1 low); serum cortisol (N: 5-25 mcg/dL): 5/21 (23.8%, 2 high, 3 low)], followed by pituitary-thyroid axis [TSH (N: 0.27-4.2 IU/mL): 6/21 (28.5%, 4 high, 2 low); free thyroxine (N: 0.9-1.7 ng/dL): 2/21 (9%, 0 high, 2 low)], pituitary-gonadal axis [FSH (N: 1-11 U/L): 2/21 (9%, 1 high, 1 low); LH (1-8 U/L): 1/21 (5%, 0 high, 1 low); total testosterone (N: 262-1593 ng/dL): 4/21 (19%, 0 high, 4 low)]; and growth hormone [3/21 (N: 0 - 3 ng/mL): (14.3%, 3 high, 0 low)]. …”
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“…Kaplan-Meier analysis revealed that NPDCD4 expression was associated with a longer overall survival (OS) and disease-free survival (DFS) in LumA-like (P = 0.008 and P = 0.028, respectively) and LumB-like (P = 0.004 and P = 0.012, respectively) subtypes. …”
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“…Additional endocrine testing showed TSH 6.4 mIU/L (n 0.3–4.2 mIU/L), free T4 1.1 ng/dL (n 0.9–1.7 ng/dL), and TPO antibody <0.3 IU/mL (n <9.0 IU/mL). …”
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“…A heterozygous pathogenic missense variant in the DIO1 gene (c.282C>A:p.N94K; N-linker) was identified in four family members with relatively higher serum rT(3), T(4,) and free T(4) than unaffected relatives, and normal TSH. …”
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“…All the subjects underwent cardiac MRI examinations on a 3T MRI scanner (MAGNETOM Trio a Tim System, Siemens Healthcare, Erlangen, Germany), including steady-state free-precession (SSFP) cine imaging and modified Look-Locker inversion recovery (MOLLI) imaging for T1 mapping. …”
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“…Participants were grouped according to free triiodothyronine [FT3] tertiles [low 2.3±0.8; medium 3.5±0.4; high 10.9±0.9 pg/ml]. …”
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“…Blood work on 09/24 showed: random cortisol 0.67 microg/dL, TSH 0.19 mIU/mL, free T4: 0.63 ng/dL, ACTH 11 pg/mL, LH 2.4 mIU/mL, FSH 4.7 MIU/mL, testosterone 13 ng/dl. …”
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“…Among the subjects who developed IH, the median TSH was 0.37 µIU/mL (0.01 - 62.39 µIU/mL) with a free T4 of 0.74 ng/dL (0.25-1.86 ng/dL) and the median cortisol was 0.80 µg/dL (0.25-24.5 µg/dL). …”
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“…CS had unilateral adrenal tumors in 6 cases and bilateral in 2 (size: 11.0 -200.0 mm; density (UH) <10.0: n= 7 and >10.0: n=1).All subjects collected 24-hour urine for urinary free cortisol (UFC). After the urine collection, they obtained whole saliva samples at 23 h for cortisol (SAF(23)). …”
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“…Diagnosis of endogenous Cushing’s syndrome entails corticotropic autonomy, lack of circadian rhythm and/or hypercortisolism, evaluated through 24h urinary free cortisol (UFC). Hair cortisol measurement (HCM) has been described as an alternative marker of cortisol exposure over the preceding three months. …”
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“…Lab parameters (HbA1c, cortisol, free thyroxine) were stable and generally remained within the normal range throughout the trials. …”
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“…PCOS women with detectable AMH had higher serum AMH (10.82 [6.74–13.40] ng/mL, Median [IQR]), total/free testosterone (T) (total T: 55.5 [49.5–62.5] ng/dL; fT: 5.65 [4.75–6.6] pg/mL) levels and greater total antral follicle numbers (AFNs) (46 [39–59] follicles) than controls (AMH: 4.03 [2.47–6.11] ng/ml; total T: 30 [24.5–34.5] ng/dL; fT: 2.2 [1.8–2.45] pg/mL; AFNs 16 [14.5–21.5] follicles, P<0.05, all values), along with a trend toward LH hypersecretion (P=0.06). …”
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“…During a median follow-up period of 30.5 months, 84 patients survived without relapse, 9 experienced tumour recurrence, and 4 died. The 2-year event-free survival (EFS) and overall survival (OS) rates were 89.4 ± 3.4%, and 95.2 ± 2.4%, respectively; they were significantly better among patients without metastasis (no metastasis vs metastasis: EFS, 93.5 ± 3.7% vs 46.7 ± 19.0%, adjusted p = 0.002. …”
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“…Images were processed using FreeSurfer (version 5.3) and the Desikan-Killiany atlas was used to extract the volumes of bilateral hippocampi, superior frontal, rostral and caudal middle frontal cortices as well as the whole brain volume. …”
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“…Of the probands 187 were diagnosed with SZ, 150 with BPP (psychosis type), 113 with SA disorders; after biotyping the same probands were categorized into three biotypes: 118 biotype 1 (BP1), 142 biotype 2 (BP2), 187 biotype 3 (BP3). 3T MRI data were quality checked and processed with FreeSurfer 6.0. The HP measures extracted were: the whole HP, and further HP subfields according to aHP and pHP. aHP and pHP subfields were reconstituted into left and right aHP and pHP. …”
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“…Simply testing patients on new information versus having them spend the same amount of time re-studying that information led to the same improvement in free recall following a one-week delay as what was seen in healthy volunteers. …”
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“…The eye movement indexes of smooth pursuit eye movement, fixation stability and free browsing were collected, so as to investigate the effects of left-behind on static attention retention, visual tracking and face recognition in social scenes. …”
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“…Structural T1 images underwent visual quality control, were realigned and parcellated into 176 gray and white matter regions using FreeSurfer software. Preliminary analyses were conducted comparing 1) MMP-9 levels between groups and 2) relating MMP-9 levels to ChP volume utilizing regression analyses. …”
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“…T1 and T2 weighted images were preprocessed using FreeSurfer 6.0. Freesurfer’s hippocampus subfield segmentation module was used to calculate left and right subfield volumes. …”
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“…Structural imaging data was segmented using the FreeSurfer 6.0 longitudinal pipeline. Intraclass correlation coefficients (ICCs) with a two-way mixed effects model of absolute agreement were calculated to assess intra- and inter-scanner reliability of brain morphometry. …”
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