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  1. 485821
    “…Longitudinal trends in physical and mental well-being were displayed graphically. Free-text responses reporting variables impacting well-being were semiquantified using natural language processing. …”
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    Determinants of Shielding Behavior During the COVID-19 Pandemic and Associations With Well-being Among National Health Service Patients: Longitudinal Observational Study
  2. 485822
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    Derivation and external validation of a risk score for predicting HIV-associated tuberculosis to support case finding and preventive therapy scale-up: A cohort study
  3. 485823
    “…The 3-year progression-free survival (PFS) rate was 43.33% in the test group and 26.67% in the control group; the overall survival (OS) rate was 48.33% in the test group and 33.33% in the control group; the differences were not statistically significant (P > 0.05). …”
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    Endu combined with concurrent chemotherapy and radiotherapy for stage IIB-IVA cervical squamous cell carcinoma patients
  4. 485824
    “…Routine and specialized coagulation tests were performed on patients' platelet-poor plasma at the time of study inclusion (day 0), days 3, 7 and at discharge on STAR Max®3 (Diagnostica Stago France) automated coagulation analyzer and included prothrombin time (PT), international normalized ratio (INR) (STA® -NeoPTimal), activated partial thromboplastin time (APTT) (STA® -Cephascreen), fibrinogen (STA® Liquid Fib), D-dimer (STA® LiatestD- Dimer), Protein C (STA Stachrom® Protein C), Protein S (STA® Latest Free Protein S) and Antithrombin (STA® Chrom ATIII). …”
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    A Prospective Study of Specialized Coagulation Parameters in Admitted COVID-19 Patients and Their Correlation With Acute Respiratory Distress Syndrome and Outcome
  5. 485825
    “…Historical elimination of Triatoma infestans from 125 municipalities reduced TriatoScores by ~ 27% (range, 20–44%); eight municipalities reported T. infestans since Bahia was certified free of Trypanosoma cruzi transmission by this non-native species. …”
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    TriatoScore: an entomological-risk score for Chagas disease vector control-surveillance
  6. 485826
    “…The trilacunary POT [P(V)(2)W(VI)(15)O(56)](12−) rearranges to the more stable monolacunary [α(2)-P(V)(2)W(VI)(17)O(61)](10−) (~ 62%) accompanied by release of free phosphates and shows the weakest inhibition (K(i) = 13.6 mM). …”
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    Wells–Dawson phosphotungstates as mushroom tyrosinase inhibitors: a speciation study
  7. 485827
    “…The clinicopathologic significance of circRNAs was measured through odds ratios (ORs) and their 95% confidence intervals (CIs), while the prognostic value was evaluated through hazard ratios (HRs) and their 95% CIs of overall survival (OS) and disease-free survival (DFS). Heterogeneity and publication bias were assessed. …”
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    Clinicopathologic significance and prognostic value of circRNAs in osteosarcoma: a systematic review and meta-analysis
  8. 485828
    “…RESULTS: With the highest mutation frequency among all PTPRs, PTPRD mutations in non-squamous NSCLC (ns-NSCLC) were linked to longer progression-free survivals (PFS, 324 vs 63 days, hazard ratio (HR)=0.36, p= 0.0152) and higher objective response rate (ORR, p=0.0099). …”
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    Identification and validation of tissue or ctDNA PTPRD phosphatase domain deleterious mutations as prognostic and predictive biomarkers for immune checkpoint inhibitors in non-squamous NSCLC
  9. 485829
    Publicado 2021
    “…The rates of complete hematological response, complete cytogenetic response, major molecular remission, and 5-year overall survival (OS) were not significantly different between the non-high-risk ACA and non-ACA groups (P>0.05 for all) ; however, the 5-year progression-free survival of the non-high-risk ACA group (42.0%) was significantly lower than that of the non-ACA group (74.5%) (χ(2)=4.766, P=0.029).② Of the 62 patients who progressed to CML-AP/BP during treatment, 41 patients (66.13%) had ACA, including 28 and 13 patients with high-risk and non-high-risk ACA, respectively, whereas the remaining 21 patients did not have ACA. …”
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    伴Ph阳性附加染色体异常慢性髓性白血病的生物学特征及疗效分析
  10. 485830
    “…Follow-ups were also done to investigate the 2-year progression-free survival (PFS) and Overall Survival (OS) of these patients. …”
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    The role of pre-treatment and mid-treatment 18F-FDG PET/CT imaging in evaluating prognosis of peripheral T-cell lymphoma-not otherwise specified (PTCL-NOS)
  11. 485831
    “…Co-primary endpoints were centrally assessed progression-free survival (PFS) and overall survival (OS). Secondary endpoints included time to intervention for central nervous system (CNS) disease, objective response rate, duration of response (DoR), clinical benefit rate, and safety. …”
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    Analysis of the pan-Asian subgroup of patients in the NALA Trial: a randomized phase III NALA Trial comparing neratinib+capecitabine (N+C) vs lapatinib+capecitabine (L+C) in patients with HER2+metastatic breast cancer (mBC) previously treated with two or more HER2-directed regimens
  12. 485832
    por Hackeng, Wenzel M, Brosens, Lodewijk A A, Kim, Joo Young, O'Sullivan, Roderick, Sung, You-Na, Liu, Ta-Chiang, Cao, Dengfeng, Heayn, Michelle, Brosnan-Cashman, Jacqueline, An, Soyeon, Morsink, Folkert H M, Heidsma, Charlotte M, Valk, Gerlof D, Vriens, Menno R, Nieveen van Dijkum, Els, Offerhaus, G Johan A, Dreijerink, Koen M A, Zeh, Herbert, Zureikat, Amer H, Hogg, Melissa, Lee, Kenneth, Geller, David, Marsh, J Wallis, Paniccia, Alessandro, Ongchin, Melanie, Pingpank, James F, Bahary, Nathan, Aijazi, Muaz, Brand, Randall, Chennat, Jennifer, Das, Rohit, Fasanella, Kenneth E, Khalid, Asif, McGrath, Kevin, Sarkaria, Savreet, Singh, Harkirat, Slivka, Adam, Nalesnik, Michael, Han, Xiaoli, Nikiforova, Marina N, Lawlor, Rita Teresa, Mafficini, Andrea, Rusev, Boris, Corbo, Vincenzo, Luchini, Claudio, Bersani, Samantha, Pea, Antonio, Cingarlini, Sara, Landoni, Luca, Salvia, Roberto, Milione, Massimo, Milella, Michele, Scarpa, Aldo, Hong, Seung-Mo, Heaphy, Christopher M, Singhi, Aatur D
    Publicado 2022
    “…The results were correlated with numerous clinicopathological features including relapse-free survival (RFS). RESULTS: ATRX/DAXX loss and ALT were associated with several adverse prognostic findings and distant metastasis/recurrence (p<0.001). …”
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    Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size
  13. 485833
    “…AVT02 is produced at a 100 mg/mL concentration with a citrate-free formulation. OBJECTIVES: The aim of this study was to compare the efficacy, safety and immunogenicity of AVT02 versus Humira(®) in subjects with moderate to severe chronic plaque psoriasis. …”
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    Efficacy, Safety and Immunogenicity of AVT02 Versus Originator Adalimumab in Subjects with Moderate to Severe Chronic Plaque Psoriasis: A Multicentre, Double-Blind, Randomised, Parallel Group, Active Control, Phase III Study
  14. 485834
    “…Correlative light-electron microscopy revealed that majority of the extracellular mitochondria are in free form and, on rare occasions, some are enclosed in membrane-surrounded vesicles. …”
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    Alternative mitochondrial quality control mediated by extracellular release
  15. 485835
    “…METHODS: An ICVHMs based on smoking, drinking, physical activity, diets, body mass index, waist circumference, blood pressure, blood glucose, and blood lipids, and a polygenic risk score (PRS) for HF were constructed in the China Kadoorie Biobank (CKB) of 96,014 participants and UK Biobank (UKB) of 335,782 participants which were free from HF and severe chronic diseases at baseline. …”
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    Modification effect of ideal cardiovascular health metrics on genetic association with incident heart failure in the China Kadoorie Biobank and the UK Biobank
  16. 485836
    “…Children’s exposure to tobacco declined substantially in years following the introduction of smoke-free legislation, with smoking uptake and perceived smoking norms declining. …”
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    Changes in childhood experimentation with, and exposure to, tobacco and e-cigarettes and perceived smoking norms: a repeated cross-sectional study of 10–11 year olds’ in Wales
  17. 485837
    “…Total 25(OH)D [t-25(OH)D] and ratios of 25(OH)D2/25(OH)D3 and C3-epi/25(OH)D3 were then respectively calculated. Free 25(OH)D [f-25(OH)D] was also measured. RESULTS: 25(OH)D3 and f-25(OH)D levels in short-stature subgroups 2 (school age: 7~12 years old) and 3 (adolescence: 13~18 years old) were significantly lower compared with those of healthy controls. …”
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    Vitamin D Status in Children With Short Stature: Accurate Determination of Serum Vitamin D Components Using High-Performance Liquid Chromatography–Tandem Mass Spectrometry
  18. 485838
    “…METHODS: Using self-reported questionnaires, chronic fatigue and quality of life are compared between 134 ovarian cancer survivors (cancer-free ≥2 years after treatment) treated with surgery and chemotherapy and 2 control groups (67 ovarian cancer survivors treated with surgery alone and 67 age-matched healthy women). …”
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    “Chronic fatigue, quality of life and long-term side-effects of chemotherapy in patients treated for non-epithelial ovarian cancer: national case-control protocol study of the GINECO-Vivrovaire rare tumors INCa French network for rare malignant ovarian tumors”
  19. 485839
    “…OBJECTIVE: Our aim was to pilot acT1ve in a free-living setting to assess its acceptability and functionality, and gather feedback on the user experience before testing it in a larger clinical trial. …”
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    A Novel Mobile Health App to Educate and Empower Young People With Type 1 Diabetes to Exercise Safely: Prospective Single-Arm Mixed Methods Pilot Study
  20. 485840
    “…METHODS: The cohort comprised 3081 participants over 35 years old who were free of CVDs. They were selected through multi-stage cluster sampling in Isfahan, Iran. …”
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    Long-term exposure to PM(2.5) and cardiovascular disease incidence and mortality in an Eastern Mediterranean country: findings based on a 15-year cohort study
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