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485981“…The IRL classifier could availably classify patients into the low-risk and high-risk groups based on the different endpoints, including recurrence-free survival (RFS) and overall survival (OS). In terms of predictive ability and clinical utility, the IRL classifier was superior to other clinical characteristics. …”
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485982por Palanimuthu, Asvinkumar“…In the sessions, possible causes of these symptoms were discussed, his family members were also psycho-educated about the psychosomatic nature of the symptoms and advised to encourage him for a symptom-free lifestyle. They were also given an instruction not to pay attention to his complaints of physical nature. …”
Publicado 2022
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485983por Parveen, Farzana, Madni, Asadullah, Torchilin, Vladimir P, Rehman, Mubashar, Jamshaid, Talha, Filipczak, Nina, Rai, Nadia, Khan, Muhammad Muzamil, Khan, Muhammad Imran“…Hemolysis assay and acute toxicity studies with drug-free and doxorubicin lipid nanocarrier formulations provided evidence for their non-toxic nature. …”
Publicado 2022
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485984por Kaboré, Jean Moise Tanga, Siribié, Mohamadou, Hien, Denise, Soulama, Issiaka, Barry, Nouhoun, Nombré, Yacouba, Dianda, Frederic, Baguiya, Adama, Tiono, Alfred Bewendtaoré, Burri, Christian, Tchouatieu, André-Marie, Sirima, Sodiomon Bienvenu“…Behaviour change regarding malaria treatment and free medication for children under five were the main reasons for participants to seek care at health centres. …”
Publicado 2022
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485985por Carril-Ajuria, Lucia, Desnoyer, Aude, Meylan, Maxime, Dalban, Cécile, Naigeon, Marie, Cassard, Lydie, Vano, Yann, Rioux-Leclercq, Nathalie, Chouaib, Salem, Beuselinck, Benoit, Chabaud, Sylvie, Barros-Monteiro, Janice, Bougoüin, Antoine, Lacroix, Guillaume, Colina-Moreno, Irelka, Tantot, Florence, Boselli, Lisa, De Oliveira, Caroline, Fridman, Wolf Herve, Escudier, Bernard, Sautes-Fridman, Catherine, Albiges, Laurence, Chaput-Gras, Nathalie“…The association of blood and tissue-based biomarkers, with overall survival (OS), progression-free survival (PFS) and response was analyzed. RESULTS: Among the 44 patients, baseline unswitched memory B cells (NSwM B cells) were enriched in responders (p=0.006) and associated with improved OS (HR=0.08, p=0.002) and PFS (HR=0.54, p=0.048). …”
Publicado 2022
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485986por Saad, Mariam, Lee, Sandra J., Tan, Aik Choon, El Naqa, Issam M., Hodi, F. Stephen, Butterfield, Lisa H., LaFramboise, William A., Storkus, Walter, Karunamurthy, Arivarasan D., Conejo-Garcia, Jose, Hwu, Patrick, Streicher, Howard, Sondak, Vernon K., Kirkwood, John M., Tarhini, Ahmad A.“…Forest plots were created to compare overall survival (OS) and relapse free survival (RFS) between ipi and HDI. Gene expression profiling (GEP) was performed on tumors of 718 (454 male, 264 female) patients. …”
Publicado 2022
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485987por Lamoureux, Audrey-Anne, Fisher, Michael, Lemelle, Lauriane, Pfaff, Elke, Kramm, Christof, De Wilde, Bram, Kazanowska, Bernarda, Hutter, Caroline, Pfister, Stefan M, Sturm, Dominik, Jones, David, Orbach, Daniel, Pierron, Gaëlle, Raskin, Scott, Drilon, Alexander, Diamond, Eli, Harada, Guilherme, Zapotocky, Michal, Ellezam, Benjamin, Weil, Alexander G, Venne, Dominic, Barritault, Marc, Leblond, Pierre, Coltin, Hallie, Hammad, Rawan, Tabori, Uri, Hawkins, Cynthia, Hansford, Jordan R, Meyran, Deborah, Erker, Craig, McFadden, Kathryn, Sato, Mariko, Gottardo, Nicholas G, Dholaria, Hetal, Nørøxe, Dorte Schou, Goto, Hiroaki, Ziegler, David S, Lin, Frank Y, Parsons, Donald Williams, Lindsay, Holly, Wong, Tai-Tong, Liu, Yen-Lin, Wu, Kuo-Sheng, Franson, Andrea Flynn, Hwang, Eugene, Aguilar-Bonilla, Ana, Cheng, Sylvia, Cacciotti, Chantel, Massimino, Maura, Schiavello, Elisabetta, Wood, Paul, Hoffman, Lindsey M, Cappellano, Andréa, Lassaletta, Alvaro, Van Damme, An, Llort, Anna, Gerber, Nicolas U, Ceruso, Mariella Spalato, Bendel, Anne E, Skrypek, Maggie, Hamideh, Dima, Mushtaq, Naureen, Walter, Andrew, Jabado, Nada, Alsahlawi, Aysha, Farmer, Jean-Pierre, Abadi, Christina Coleman, Mueller, Sabine, Mazewski, Claire, Aguilera, Dolly, Robison, Nathan, O’Halloran, Katrina, Abbou, Samuel, Berlanga, Pablo, Geoerger, Birgit, Øra, Ingrid, Moertel, Christopher L, Razis, Evangelia D, Vernadou, Anastasia, Doz, François, Laetsch, Theodore W, Perreault, Sébastien“…For LGG the median progression-free survival (PFS) after the first line of treatment was 17 months (95% CI: 0.0-35.5) and median overall survival (OS) was not reached. …”
Publicado 2022
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485988por Cozzi, Salvatore, Alì, Emanuele, Bardoscia, Lilia, Najafi, Masoumeh, Botti, Andrea, Blandino, Gladys, Giaccherini, Lucia, Ruggieri, Maria Paola, Augugliaro, Matteo, Iori, Federico, Sardaro, Angela, Iotti, Cinzia, Ciammella, Patrizia“…The clinical outcome seems to be very encouraging with 1-year local control (LC), overall survival (OS) and progression-free survival (PFS) rates ranging from 84 to 94%, 53 to 88% and 23 to 53.9%, respectively. …”
Publicado 2022
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485989por Gilles, Liese, Govarts, Eva, Rodriguez Martin, Laura, Andersson, Anna-Maria, Appenzeller, Brice M. R., Barbone, Fabio, Castaño, Argelia, Coertjens, Dries, Den Hond, Elly, Dzhedzheia, Vazha, Eržen, Ivan, López, Marta Esteban, Fábelová, Lucia, Fillol, Clémence, Franken, Carmen, Frederiksen, Hanne, Gabriel, Catherine, Haug, Line Småstuen, Horvat, Milena, Halldórsson, Thórhallur Ingi, Janasik, Beata, Holcer, Nataša Janev, Kakucs, Réka, Karakitsios, Spyros, Katsonouri, Andromachi, Klánová, Jana, Kold-Jensen, Tina, Kolossa-Gehring, Marike, Konstantinou, Corina, Koponen, Jani, Lignell, Sanna, Lindroos, Anna Karin, Makris, Konstantinos C., Mazej, Darja, Morrens, Bert, Murínová, Ľubica Palkovičová, Namorado, Sónia, Pedraza-Diaz, Susana, Peisker, Jasmin, Probst-Hensch, Nicole, Rambaud, Loïc, Rosolen, Valentina, Rucic, Enrico, Rüther, Maria, Sarigiannis, Dimosthenis, Tratnik, Janja Snoj, Standaert, Arnout, Stewart, Lorraine, Szigeti, Tamás, Thomsen, Cathrine, Tolonen, Hanna, Eiríksdóttir, Ása, Van Nieuwenhuyse, An, Verheyen, Veerle J., Vlaanderen, Jelle, Vogel, Nina, Wasowicz, Wojciech, Weber, Till, Zock, Jan-Paul, Sepai, Ovnair, Schoeters, Greet“…In October 2020 the EU commission published its new chemicals strategy for sustainability towards a toxic-free environment. The European Parliament called upon the commission to collect human biomonitoring data to support chemical’s risk assessment and risk management. …”
Publicado 2022
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485990por van Eekelen, R, van Geloven, N, van Wely, M, Bhattacharya, S, van der Veen, F, Eijkemans, M J, McLernon, D J“…Despite adjustment for the three most important prognostic patient characteristics, namely female age, duration of subfertility and primary or secondary subfertility, our estimates might not be free from residual confounding. WIDER IMPLICATIONS OF THE FINDINGS: IVF should be used selectively based on judgements on gain compared to continuing expectant management for a given couple. …”
Publicado 2019
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485991por Li, Jian-Xu, Deng, Wen-Xiang, Huang, Shi-Ting, Lin, Xiao-Feng, Long, Mei-Ying, Zhang, Jie, Su, Ting-Shi, Li, Li-Qing, Pang, Ya-Dan, Liang, Chun-Feng, Zhou, Hong-Mei, Lu, Hai-Yan, Liang, Shi-Xiong, Xiang, Bang-De“…BACKGROUND: The combination of transcatheter arterial chemoembolization (TACE) plus sorafenib prolonged progression-free survival (PFS) and overall survival (OS) than sorafenib or TACE monotherapy for patients with hepatocellular carcinoma (HCC). …”
Publicado 2022
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485992por Namango, Isaac Haggai, Marshall, Carly, Saddler, Adam, Ross, Amanda, Kaftan, David, Tenywa, Frank, Makungwa, Noely, Odufuwa, Olukayode G., Ligema, Godfrey, Ngonyani, Hassan, Matanila, Isaya, Bharmal, Jameel, Moore, Jason, Moore, Sarah J., Hetzel, Manuel W.“…The Centres for Disease Control light trap (CDC-LT) and the human decoy trap (HDT) are exposure-free alternatives. This study compared the CDC-LT and HDT against HLC for measuring Anopheles biting in rural Tanzania and assessed their suitability as HLC proxies. …”
Publicado 2022
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485993“…Compared to the NUSAP1 low expression group, the NUSAP1 high expression group was more likely to also have lymph node metastasis, pathological PTC type, shorter progression-free survival (PFS), and higher scores for immune checkpoint inhibitor treatment. …”
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485994por Wang, Zhenghang, Zhang, Qi, Qi, Changsong, Bai, Yuezong, Zhao, Feilong, Chen, Hui, Li, Zhongwu, Wang, Xicheng, Chen, Mifen, Gong, Jifang, Peng, Zhi, Zhang, Xiaotian, Cai, Jinping, Chen, Shiqing, Zhao, Xiaochen, Shen, Lin, Li, Jian“…RESULTS: AKT1 and CDH1 mutations were identified as independent predictors of poor progression-free survival (PFS) and primary resistance to ICIs in dMMR/MSI-H GI cancer. …”
Publicado 2022
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485995por Ricciuti, Biagio, Wang, Xinan, Alessi, Joao V., Rizvi, Hira, Mahadevan, Navin R., Li, Yvonne Y., Polio, Andrew, Lindsay, James, Umeton, Renato, Sinha, Rileen, Vokes, Natalie I., Recondo, Gonzalo, Lamberti, Giuseppe, Lawrence, Marissa, Vaz, Victor R., Leonardi, Giulia C., Plodkowski, Andrew J., Gupta, Hersh, Cherniack, Andrew D., Tolstorukov, Michael Y., Sharma, Bijaya, Felt, Kristen D., Gainor, Justin F., Ravi, Arvind, Getz, Gad, Schalper, Kurt A., Henick, Brian, Forde, Patrick, Anagnostou, Valsamo, Jänne, Pasi A., Van Allen, Eliezer M., Nishino, Mizuki, Sholl, Lynette M., Christiani, David C., Lin, Xihong, Rodig, Scott J., Hellmann, Matthew D., Awad, Mark M.“…MAIN OUTCOMES AND MEASURES: Association of TMB levels with objective response rate (ORR), progression-free survival (PFS), and overall survival (OS). RESULTS: In the entire cohort of 1552 patients with advanced NSCLC who received PD-1/PD-L1 blockade, the median (range) age was 66 (22-92) years, 830 (53.5%) were women, and 1347 (86.8%) had cancer with nonsquamous histologic profile. …”
Publicado 2022
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485996por Zeng, Mengyao, Yang, Liu, Mao, Yanyan, He, Yang, Li, Min, Liu, Jun, Zhu, Qianxi, Chen, Liang, Zhou, Weijin“…A total of 57,586 women (57,708 pregnancies) from all 39 counties of Chongqing who participated in the National Free Preconception Health Examination Project were included. …”
Publicado 2022
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485997por Wolf, Jule, Kurz, Steffen, Rothe, Thomas, Serpa, Marco, Scholber, Jutta, Erbes, Thalia, Gkika, Eleni, Baltas, Dimos, Verma, Vivek, Krug, David, Juhasz-Böss, Ingolf, Grosu, Anca-Ligia, Nicolay, Nils H., Sprave, Tanja“…BACKGROUND: Radiotherapy using the deep inspiration breath-hold (DIBH) technique compared with free breathing (FB) can achieve substantial reduction of heart and lung doses in left-sided breast cancer cases. …”
Publicado 2022
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485998por Tawbi, Hussein A, Robert, Caroline, Brase, Jan C, Gusenleitner, Daniel, Gasal, Eduard, Garrett, James, Savchenko, Alexander, Görgün, Güllü, Flaherty, Keith T, Ribas, Antoni, Dummer, Reinhard, Schadendorf, Dirk, Long, Georgina V, Nathan, Paul D, Ascierto, Paolo A“…BACKGROUND: The randomized phase 3 COMBI-i trial did not meet its primary endpoint of improved progression-free survival (PFS) with spartalizumab plus dabrafenib and trametinib (sparta-DabTram) vs placebo plus dabrafenib and trametinib (placebo-DabTram) in the overall population of patients with unresectable/metastatic BRAF V600-mutant melanoma. …”
Publicado 2022
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485999por Ursini, Lucia Anna, Nuzzo, Marianna, Rosa, Consuelo, Borgia, Marzia, Caravatta, Luciana, Di Tommaso, Monica, Trignani, Marianna, Di Guglielmo, Fiorella Cristina, Ausili Cefaro, Giampiero, Angelucci, Domenico, Muzi, Marzia, Martino, Gianluigi, Cianchetti, Ettore, Grossi, Simona, Tavoletta, Saveria, Brocco, Davide, Grassadonia, Antonino, Tinari, Nicola, Gildetti, Simona, D’Ostilio, Nicola, Stuppia, Liborio, Porreca, Annamaria, Di Nicola, Marta, Genovesi, Domenico“…RESULTS: In all, 199 patients underwent conservative surgery and SLN biopsy; 133 patients meeting criteria were analysed: 41 patients (30.8%) pN1mic and 92 (69.2%) pN1a. The 5‑year disease-free survival (DFS) was 95.0% (85.9–100%) in group 1 and 93.0% (86.3–100.0%) in group 2 (p = 0.78). …”
Publicado 2022
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486000por Baskal, Svetlana, Kaiser, Annette, Mels, Catharina, Kruger, Ruan, Tsikas, Dimitrios“…Selected-ion monitoring of m/z 811 and m/z 814 was used in quantitative analyses. Free Hyp was found in spot urine samples (10 µL) of two healthy subjects at 0.60 µM (0.29 µmol Hyp/mmol creatinine) in the female and 1.80 µM (0.19 µmol Hyp/mmol creatinine) in the male subject. …”
Publicado 2022
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