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486041por Greene, M. A., Udoka, A. N. S., Powell, R. R., Noorai, R. E., Bruce, T., Duckett, S. K.“…BACKGROUND: Longissimus muscle samples were collected from lambs exposed in utero to mycotoxins [E-, endophyte-free tall fescue seed without ergot alkaloids (negative control) or E + , endophyte-infected tall fescue seed containing ergot alkaloids] during mid-gestation (MID; E + /E-) or late-gestation (LATE; E-/E +) harvested at two developmental stages (FETAL, gestational d133) or (MAT, near maturity, 250 d of age; n = 3/treatment/developmental stage). …”
Publicado 2022
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486042“…METHODS: This retrospective observational cohort study evaluated patients from the Flatiron MM Core Registry who received VRd as first LOT between November 1, 2015, and February 28, 2021. Progression-free survival (PFS) was analyzed using the Kaplan-Meier method. …”
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486043por Lan, Wang, Lihong, Liu, Chun, Han, Shutang, Liu, Qi, Wang, Liang, Xu, Xiaoning, Li, Likun, Liu“…The median progression-free survival (PFS) in the SD-IMRT and SIB-IMRT groups was 22 and 19 months, respectively, and the median overall survival duration was 24 and 22 months, respectively, with χ(2) = 0.244 and P = 0.621. …”
Publicado 2022
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486044“…Use of the acidic transesterification method can avoid side reactions, such as the conversion of 3-chloropropanediol, 2-chloropropanediol, and 3-bromopropanediol to free glycidol under alkaline conditions. The method developed in this study was more efficient, and the results were more accurate and reproducible. …”
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486045por CHEN, Guohong, GUO, Zehua, CAO, Yiren, FAN, Liuyin, LIU, Weiwen, MA, Yixin, CAO, Chengxi, ZHANG, Qiang“…The EE model has the following advantages: (i) increase in specificity by eluting FITC absorbed to the surface of beads; (ii) high efficiency in the removal of free FITC with more than 97% clearance; (iii) rapid decrease in noise in the mass hydrogel (within 30 min). …”
Publicado 2022
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486046por KE, Qingqing, LI, Shiyan, WANG, Dingnan, ZHOU, Qin, ZHOU, Fan, BEI, Yijiang, CHEN, Xiaoming, WANG, Yang“…Sixty fishery drug samples were evaluated, among which eight Chinese herbal medicine samples were found to contain unspecified ingredients and one antibiotic sample was found to be free of any active substances. Thus, an effective technical method to monitor the quality and safety of fishery drugs was developed.…”
Publicado 2022
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486047por Dong, Min, Zhang, Lu, Wu, Pei, Feng, Lin, Jiang, Weidan, Liu, Yang, Kuang, Shengyao, Li, Shuwei, Mi, Haifeng, Tang, Ling, Zhou, Xiaoqiu“…RESULTS: Appropriate levels of dietary protein increased the feed intake, percentage weight gain, specific growth rate, body composition, unsaturated fatty acid content in muscle, partial free amino acid content in muscle, and muscle hardness of grass carp. …”
Publicado 2022
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486048por Fan, Yuanchun, Cheng, Huimin, Liu, Yueping, Liu, Shihao, Lowe, Scott, Li, Yaru, Bentley, Rachel, King, Bethany, Tuason, John Pocholo W., Zhou, Qin, Sun, Chenyu, Zhang, Hui“…Studies in OC have shown a limited effect of bevacizumab in the general population, with a slight improvement in progression-free survival (PFS) and no effect on overall survival (OS). …”
Publicado 2022
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486049por SHANG, Shiting, DONG, Hangyan, LI, Yuanyuan, ZHANG, Wanjun, LI, Hang, QIN, Weijie, QIAN, Xiaohong“…A total of 1016 N-glycoproteins and 2192 N-glycopeptides were identified in the mid-morning urine samples of the 40 healthy volunteers. A label-free quantitation strategy was used to investigate the fluctuation range of the physiologically abundant urinary N-glycopeptides. …”
Publicado 2021
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486050“…In terms of the life quality after treatment, 36 patients (50.00%) had augmented KPS score and 38 patients (52.78%) had augmented ZPS score in the observation group, which was noticeably higher compared to the control group, and the difference was statistically significant (P < 0.05). The progression-free survival (PFS) of the observation group was 31.67 months (95% confidence interval was 0.09657∼0.3019), and the PFS of the control group was 26.73 months (95% confidence interval was 3.313∼10.36). …”
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486051“…Furthermore, after 4 weeks of treatment, 74 patients (24.7%) in the cinnarizine/dimenhydrinate group were completely symptom free (MVS = 0), a significantly greater proportion than in any of the comparator groups. …”
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486052por Hasannia, Maliheh, Abnous, Khalil, Taghdisi, Seyed Mohammad, Nekooei, Sirous, Ramezani, Mohammad, Alibolandi, Mona“…The obtained data indicated highest therapeutic index for Apt-Pep@MUA.GNR-DOX compared to Pep@MUA.GNR-DOX and free DOX. Moreover, the prepared system showed capability of CT imaging of tumor tissue in 4T1 tumorized mice through tumor accumulation even 24 h post-administration. …”
Publicado 2022
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486053por Kolberg-Liedtke, Cornelia, Feuerhake, Friedrich, Garke, Madlen, Christgen, Matthias, Kates, Ronald, Grischke, Eva Maria, Forstbauer, Helmut, Braun, Michael, Warm, Mathias, Hackmann, John, Uleer, Christoph, Aktas, Bahriye, Schumacher, Claudia, Kuemmel, Sherko, Wuerstlein, Rachel, Graeser, Monika, Nitz, Ulrike, Kreipe, Hans, Gluz, Oleg, Harbeck, Nadia“…This preplanned translational analysis assessed impacts of sTIL measurements at baseline (sTIL-0) and after 3 weeks of chemotherapy (sTIL-3) on pCR and invasive disease-free survival (iDFS). Predictive performance of sTIL-0 and sTIL-3 for pCR was quantified by ROC analysis and logistic regression; Kaplan–Meier estimation and Cox regression (with mediation analysis) were used to determine their impact on iDFS. …”
Publicado 2022
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486054por Sodhi, Punita K, Shaw, Ekta, Gautam, Akanksha, Yadav, Alka, R, Archana T, Rao, Kavya C, Sharma, Shantanu, Tewari, Ruchir“…Objective: The foveal avascular zone (FAZ) is the round capillary-free zone within the macula and is supplied only by a single-layered parafoveal capillary arcade. …”
Publicado 2022
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486055por Zhan, Shukai, Liu, Caiguang, Li, Na, Li, Tong, Tian, Zhenyi, Zhao, Min, Wu, Dongxuan, Chen, Minhu, Zeng, Zhirong, Zhuang, Xiaojun“…DATA SOURCES AND METHODS: This meta-analysis was conducted following the PRISMA guidelines. Free-text words and subject terms, including ‘Behcet’s Syndrome’, ‘Biologics’, ‘Tumor Necrosis Factor Antagonist’, were used to systematically research the relevant studies in the electronic databases (PubMed, Web of Science, Embase, and Cochrane Library). …”
Publicado 2022
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486056por Powell-Wiley, Tiffany M, Martinez, Marie F, Tamura, Kosuke, Neally, Sam J, O'Shea, Kelly J, Curlin, Kaveri, Albarracin, Yardley, Vijayakumar, Nithya P, Morgan, Matthew, Ortiz-Chaparro, Erika, Bartsch, Sarah M, Osei Baah, Foster, Wedlock, Patrick T, Ortiz-Whittingham, Lola R, Scannell, Sheryl, Potharaju, Kameswari A, Randall, Samuel, Solano Gonzales, Mario, Domino, Molly, Ranganath, Kushi, Hertenstein, Daniel, Syed, Rafay, Weatherwax, Colleen, Lee, Bruce Y“…METHODS: We developed our Virtual Population Obesity Prevention, agent-based model of Washington, DC, to simulate the impact of a place-tailored digital health app that provides information about free recreation center classes on PA, BMI, and overweight and obesity prevalence among African American women. …”
Publicado 2022
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486057por Lu, Yitian, Zhang, Jintao, Zeng, Fanning, Wang, Peng, Guo, Xiangna, Wang, Haitao, Qin, Zaisheng, Tao, Tao“…BACKGROUND: Mesenchymal stem cell (MSCs)-derived small Extracellular Vesicles (sEVs) are considered as a new cell-free therapy for pain caused by nerve injury, but whether human placental mesenchymal stem cell-derived sEVs relieve pain in sciatic nerve injury and its possible mechanism are still unclear. …”
Publicado 2022
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486058por Li, Zhenhui, Zhu, Haibin, Pang, Xiaolin, Mao, Yun, Yi, Xiaoping, Li, Chunxia, Lei, Ming, Cheng, Xianshuo, Liang, Lei, Wu, Jiamei, Ding, Yingying, Yang, Jun, Sun, Yingshi, Zhang, Tao, You, Dingyun, Liu, Zaiyi“…Based on Cox models, associations of preoperative CA19-9 with recurrence-free survival (RFS) and overall survival (OS) were evaluated in patients with or without elevated CEA, and interactions between CEA and CA19-9 were also calculated. …”
Publicado 2022
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486059por Huang, Ying, Ma, Jieyi, Yang, Cuiyun, Wei, Paijia, Yang, Minghui, Han, Hui, Chen, Hua Dong, Yue, Tianfang, Xiao, Shu, Chen, Xuanyu, Li, Zuoqing, Tang, Yanlai, Luo, Jiesi, Lin, Shuibin, Huang, Libin“…Despite existing therapy approaches, the 5-year event-free survival (EFS) for patients with advanced NBL remains below 30%, emphasizing urgent necessary for novel therapeutic strategies. …”
Publicado 2022
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486060por Schinke, Henrik, Shi, Enxian, Lin, Zhongyang, Quadt, Tanja, Kranz, Gisela, Zhou, Jiefu, Wang, Hongxia, Hess, Julia, Heuer, Steffen, Belka, Claus, Zitzelsberger, Horst, Schumacher, Udo, Genduso, Sandra, Riecken, Kristoffer, Gao, Yujing, Wu, Zhengquan, Reichel, Christoph A., Walz, Christoph, Canis, Martin, Unger, Kristian, Baumeister, Philipp, Pan, Min, Gires, Olivier“…Furthermore, a logistic regression model defined ITGB4 as a predictive marker of progression-free survival in response to Cetuximab in recurrent metastatic HNSCC patients. …”
Publicado 2022
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