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  1. 486181
    “…This protocol details an implementation study of mailing free HIV self-tests (HIVSTs) nested within a randomized controlled trial designed to assess the benefit of a mobile phone app for increasing the uptake of HIV prevention and other social services. …”
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    Engaging Black or African American and Hispanic or Latino Men Who Have Sex With Men for HIV Testing and Prevention Services Through Technology: Protocol for the iSTAMP Comparative Effectiveness Trial
  2. 486182
    “…RESULTS: Our results showed high NUF2 expression in OC tissues and OC cell lines, which was associated with shorter overall survival and progression-free survival in patients. NUF2 depletion by siRNA suppressed the proliferation abilities and induced cell apoptosis of OC cells in vitro, and impeded OC growth in vivo. …”
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    NUF2 promotes tumorigenesis by interacting with HNRNPA2B1 via PI3K/AKT/mTOR pathway in ovarian cancer
  3. 486183
    “…Outcomes included progression-free survival (PFS), overall survival (OS), objective response rate (ORR), and rate of grade 3–4 toxicity assessment. …”
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    Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy
  4. 486184
    “…METHODS: Integrated proteomics and metabolomics analysis were performed for plasma-derived exosomes collected from tumor-free controls (TFC), PCa and CRPC patients. Expression of specific exosomal proteins were further validated by targeted 4D-parallel reaction monitoring (PRM) mass spectrometry among the three cohorts. …”
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    Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer
  5. 486185
    “…The median progression-free survival (PFS) was 4.67 months (95% confidence interval [CI], 2.91–6.42) in the AG group and 3.33 months (95% CI, 1.87–4.79, p = 0.106) in the FFX group. …”
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    The efficacy and safety of Nab-paclitaxel plus gemcitabine versus mFOLFIRINOX in the first-line treatment of metastatic pancreatic cancer: a retrospective study
  6. 486186
    “…The Kaplan-Meier method was used for outcomes of interest, including local control (LC), locoregional control, distant metastatic control, progression-free survival, and overall survival (OS). Cox proportional hazards regression modeling was used to assess associations of covariates with OS. …”
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    Evaluation of Proton Therapy Reirradiation for Patients With Recurrent Head and Neck Squamous Cell Carcinoma
  7. 486187
    “…A single reviewer extracted free-text data relevant to clinical AI implementation, noting the stakeholders contributing to each excerpt. …”
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    Stakeholder Perspectives of Clinical Artificial Intelligence Implementation: Systematic Review of Qualitative Evidence
  8. 486188
    “…DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study included incident patients with type 2 diabetes who were free of cardiovascular disease and cancer at the time of diabetes diagnosis and completed the diabetes supplementary questionnaires in the Nurses’ Health Study (in 2000 and 2005) and the Health Professionals Follow-Up Study (in 2000, 2004, and 2008) in the US. …”
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    Adherence to a Healthy Lifestyle in Association With Microvascular Complications Among Adults With Type 2 Diabetes
  9. 486189
    “…The web-based assessment was free and could be found via search engines, but attention was also drawn to the service via newspaper articles, radio reports, and podcasts. …”
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    Internet-Based Self-Assessment for Symptoms of Internet Use Disorder—Impact of Gender, Social Aspects, and Symptom Severity: German Cross-sectional Study
  10. 486190
    “…Study subjects were paired with comparison counterparts free of both diseases using Propensity Score Matching at a 1:1 ratio. …”
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    Disparities in the medical expenditures of patients with cancer and concomitant mental disorder: analyzing the effects of diagnosis sequence order
  11. 486191
    por Haas, Shalaila S, Ge, Ruiyang, Agartz, Ingrid, Amminger, G. Paul, Andreassen, Ole A, Bachman, Peter, Baeza, Inmaculada, Choi, Sunah, Colibazzi, Tiziano, Cropley, Vanessa L, de la Fuente-Sandoval, Camilo, Ebdrup, Bjørn H, Fortea, Adriana, Fusar-Poli, Paolo, Glenthøj, Birte Yding, Glenthøj, Louise Birkedal, Haut, Kristen M, Hayes, Rebecca A, Heekeren, Karsten, Hooker, Christine I, Hwang, Wu Jeong, Jahanshad, Neda, Kaess, Michael, Kasai, Kiyoto, Katagiri, Naoyuki, Kim, Minah, Kindler, Jochen, Koike, Shinsuke, Kristensen, Tina D, Kwon, Jun Soo, Lawrie, Stephen M, Lee, Jimmy, Lemmers-Jansen, Imke LJ, Lin, Ashleigh, Ma, Xiaoqian, Mathalon, Daniel H, McGuire, Philip, Michel, Chantal, Mizrahi, Romina, Mizuno, Masafumi, Møller, Paul, Mora-Durán, Ricardo, Nelson, Barnaby, Nemoto, Takahiro, Nordentoft, Merete, Nordholm, Dorte, Omelchenko, Maria A, Pantelis, Christos, Pariente, Jose C, Raghava, Jayachandra M, Reyes-Madrigal, Francisco, Røssberg, Jan I, Rössler, Wulf, Salisbury, Dean F, Sasabayashi, Daiki, Schall, Ulrich, Smigielski, Lukasz, Sugranyes, Gisela, Suzuki, Michio, Takahashi, Tsutomu, Tamnes, Christian K, Theodoridou, Anastasia, Thomopoulos, Sophia I, Thompson, Paul M, Tomyshev, Alexander S, Uhlhaas, Peter J, Værnes, Tor G, van Amelsvoort, Therese AMJ, van Erp, Theo GM, Waltz, James A, Wenneberg, Christina, Westlye, Lars T, Wood, Stephen J, Zhou, Juan H, Hernaus, Dennis, Jalbrzikowski, Maria, Kahn, René S, Corcoran, Cheryl M, Frangou, Sophia
    Publicado 2023
    “…DESIGN, SETTING, AND PARTICIPANTS: Clinical, IQ and FreeSurfer-derived regional measures of cortical thickness (CT), cortical surface area (SA), and subcortical volume (SV) from 1,340 CHR-P individuals [47.09% female; mean age: 20.75 (4.74) years] and 1,237 healthy individuals [44.70% female; mean age: 22.32 (4.95) years] from 29 international sites participating in the ENIGMA Clinical High Risk for Psychosis Working Group. …”
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    Normative modeling of brain morphometry in Clinical High-Risk for Psychosis
  12. 486192
    “…Additionally, the FMT of fecal microbiota from the PA-treated TgCRND8 mice significantly alleviated the cognitive impairments and AD-like pathologies in the germ-free TgCRND8 mice. CONCLUSION: All these findings amply demonstrated that PA could ameliorate the cognitive deficits in TgCRND8 mice via suppressing Aβ plaques deposition, hyperphosphorylation of tau protein, neuroinflammation and gut dysbiosis through inhibiting the activation of C/EBPβ/AEP pathway, suggesting that PA is a promising naturally occurring chemical worthy of further development into the pharmaceutical treatment of AD.…”
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    Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer’s disease via modulating neuropathology and gut microbiota through suppressing C/EBPβ/AEP pathway
  13. 486193
    “…RESULTS: In the discovery cohort, 17 of 108 (15.7%) patients had detectable ctDNA. ctDNA-positive patients had a significantly high recurrence rate (76.5% vs. 16.5%, P < 0.001) and short recurrence-free survival (RFS; P < 0.001) versus ctDNA-negative patients. …”
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    Development and validation of postoperative circulating tumor DNA combined with clinicopathological risk factors for recurrence prediction in patients with stage I-III colorectal cancer
  14. 486194
    “…METHODS: Wild-type (WT; males, n=9; females, n=9) and TNF-Tg (males, n=12; females, n=14) mice were singly housed with free access to a running wheel starting at 2 months until 5 to 5.5 months of age. …”
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    Implementation of automated behavior metrics to evaluate voluntary wheel running effects on inflammatory-erosive arthritis and interstitial lung disease in TNF-Tg mice
  15. 486195
    “…MAIN OUTCOMES AND MEASURES: Patients with CH and CH-PD in peripheral blood samples were identified, and these findings were correlated with survival outcomes (progression-free survival [PFS] and overall survival [OS]) during first-line chemotherapy and ICB, as well as baseline white blood cell levels and the need for granulocyte colony-stimulating factor (G-CSF) support. …”
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    Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers
  16. 486196
    “…RESULTS: The median disease-free survival was 21.3 months and estimated median overall survival (OS) was 60 months. …”
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    Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma
  17. 486197
    “…The results showed a higher incidence of relapse among FL3a patients, in which more patients underwent histological transformation (HT) when compared to FL1-2 (P = 0.003). 1470 (76.2%) patients of the entire cohort received R-CHOP therapy; survival analysis revealed that FL3a patients had a worse progression-free survival (PFS) rate than FL1-2 patients. Survival of FL3a patients with respect to FLIPI showed an inferior PFS in the intermediate and high-risk groups than FL1-2 patients. …”
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    Differences in clinical characteristics and outcomes between patients with grade 3a and grades 1–2 follicular lymphoma: a real-world multicenter study
  18. 486198
    “…We have developed the CoronaCheck mobile health (mHealth) platform, the first free app that provides easy access to valid information about the risk of infection with SARS-CoV-2 in English and German. …”
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    Associations of Country-Specific and Sociodemographic Factors With Self-Reported COVID-19–Related Symptoms: Multivariable Analysis of Data From the CoronaCheck Mobile Health Platform
  19. 486199
    por Zhu, Hai-Dong, Li, Hai-Liang, Huang, Ming-Sheng, Yang, Wei-Zhu, Yin, Guo-Wen, Zhong, Bin-Yan, Sun, Jun-Hui, Jin, Zhi-Cheng, Chen, Jian-Jian, Ge, Nai-Jian, Ding, Wen-Bin, Li, Wen-Hui, Huang, Jin-Hua, Mu, Wei, Gu, Shan-Zhi, Li, Jia-Ping, Zhao, Hui, Wen, Shu-Wei, Lei, Yan-Ming, Song, Yu-Sheng, Yuan, Chun-Wang, Wang, Wei-Dong, Huang, Ming, Zhao, Wei, Wu, Jian-Bing, Wang, Song, Zhu, Xu, Han, Jian-Jun, Ren, Wei-Xin, Lu, Zai-Ming, Xing, Wen-Ge, Fan, Yong, Lin, Hai-Lan, Zhang, Zi-Shu, Xu, Guo-Hui, Hu, Wen-Hao, Tu, Qiang, Su, Hong-Ying, Zheng, Chuan-Sheng, Chen, Yong, Zhao, Xu-Ya, Fang, Zhu-Ting, Wang, Qi, Zhao, Jin-Wei, Xu, Ai-Bing, Xu, Jian, Wu, Qing-Hua, Niu, Huan-Zhang, Wang, Jian, Dai, Feng, Feng, Dui-Ping, Li, Qing-Dong, Shi, Rong-Shu, Li, Jia-Rui, Yang, Guang, Shi, Hai-Bin, Ji, Jian-Song, Liu, Yu-E, Cai, Zheng, Yang, Po, Zhao, Yang, Zhu, Xiao-Li, Lu, Li-Gong, Teng, Gao-Jun
    Publicado 2023
    “…The primary endpoint was progression-free survival (PFS) according to modified RECIST. …”
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    Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001)
  20. 486200
    “…METHODS: Forty-two maintenance hemodialysis (MHD) patients and 36 health controls were enrolled in this study. Plasma cell-free MtDNA was detected by TaqMan-based qPCR assay. …”
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    Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation
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