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486261por Veldhuizen, Gregory Patrick, Röcken, Christoph, Behrens, Hans-Michael, Cifci, Didem, Muti, Hannah Sophie, Yoshikawa, Takaki, Arai, Tomio, Oshima, Takashi, Tan, Patrick, Ebert, Matthias P., Pearson, Alexander T., Calderaro, Julien, Grabsch, Heike I., Kather, Jakob Nikolas“…We assessed classification performance using the Area Under the Receiver Operating Characteristic Curve (AUROC) and prognostic value (overall, cancer specific and disease free survival) of the DL-based classifier with uni- and multivariate Cox proportional hazard models and Kaplan–Meier curves with log-rank test statistics. …”
Publicado 2023
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486262“…For PD1/L1-based immunotherapy, the relatively low objective response rate (ORR), short progression-free survival (PFS) of patients, and drug resistance and recurrence especially for solid malignancy, are the major clinical challenges. …”
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486263“…UV–vis absorption maxima (λ(max)) for the free mycolactone A/B was observed at 362 nm, and the values for the adducts myco-BA15, myco-BA18, and myco-BA21 were at 272 nm, 270 nm, and 286 nm respectively. …”
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486264“…Specimens were dissected free of all soft tissues except for the glenoid labrum of the shoulder and dorsal wrist ligaments of the distal radius. …”
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486266por Mugabi, Benedicto, Nanyingi, Miisa, Kabanda, Richard, Ndibazza, Juliet, Elyanu, Peter, Asiimwe, John Baptist, Nazziwa, Gorret, Habaasa, Gilbert, Kekitiinwa, Adeodata“…This could complicate the achievement of the UNAIDS sustainable development goal (SDG) of an HIV/AIDS-free generation by 2030 because low health literacy (HL) skills can affect the efficacy of almost all HIV disease prevention and health promotion efforts. …”
Publicado 2023
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486267por Vasudevan, Harish N., Delley, Cyrille, Chen, William C., Mirchia, Kanish, Pan, Sixuan, Shukla, Poojan, Aabedi, Alex A., Nguyen, Minh P., Morshed, Ramin A., Young, Jacob S., Boreta, Lauren, Fogh, Shannon E., Nakamura, Jean L., Theodosopoulos, Philip V., Phillips, Joanna, Hervey-Jumper, Shawn L., Daras, Mariza, Pike, Luke, Aghi, Manish K., Tsai, Katy, Raleigh, David R., Braunstein, Steve E., Abate, Adam R.“…Secondary outcomes included CNS progression-free survival (PFS), microenvironmental composition with decreased T-cell and macrophage populations, and responses to immunotherapy. …”
Publicado 2023
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486268Publicado 2023“…METHODS: The polyacrylamide (PAAm) hydrogel coating was prepared by UV-induced free radical polymerization. The morphology of the PAAm coating and its interfacial bonding with the silicone rubber substrates of nasogastric tubes were observed with scanning electron microscope. …”
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486269por Jin, Aina, Kan, Zhaobo, Tan, Qiushi, Shao, Jing, Han, Qi, Chang, Yashan, An, Nan, Yi, Muqing“…We analyzed plasma triglyceride species (TGs), free amino acids (FAAs), and tricarboxylic acid (TCA) cycle intermediates using omics methods. …”
Publicado 2023
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486270por Villanueva, Vicente, Laloyaux, Cédric, D’Souza, Wendyl, Faught, Edward, Klein, Pavel, Reuber, Markus, Rosenow, Felix, Salas-Puig, Javier, Insuga, Victor Soto, Strzelczyk, Adam, Szaflarski, Jerzy P., Chinn, Chris, Daniels, Tony, Floricel, Florin, Friesen, David, Sendersky, Veronica, Besson, Hervé, Steinhoff, Bernhard J.“…Patients with missing data after BRV discontinuation were considered non-responders/not seizure free. Analyses were performed for all adult patients (≥ 16 years), and for subgroups by seizure type recorded at baseline; by number of prior antiseizure medications (ASMs) at index; by use of BRV as monotherapy versus polytherapy at index; for patients who switched from levetiracetam to BRV versus patients who switched from other ASMs to BRV; and for patients with focal-onset seizures and a BRV dose of ≤ 200 mg/day used as add-on at index. …”
Publicado 2023
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486271por Chida-Nagai, Ayako, Masaki, Naoki, Maeda, Kay, Sasaki, Konosuke, Sato, Hiroki, Muneuchi, Jun, Ochiai, Yoshie, Murayama, Hiroomi, Tahara, Masahiro, Shiono, Atsuko, Shinozuka, Atsushi, Kono, Fumihiko, Machida, Daisuke, Toyooka, Shinichi, Sugimoto, Seiichiro, Nakamura, Kazufumi, Akagi, Satoshi, Kondo, Maiko, Kasahara, Shingo, Kotani, Yasuhiro, Koizumi, Junichi, Oda, Katsuhiko, Harada, Masako, Nakajima, Daisuke, Murata, Akira, Nagata, Hazumu, Yatsunami, Koichi, Kobayashi, Tomio, Matsunaga, Yoshikiyo, Inoue, Takahiro, Yamagishi, Hiroyuki, Nakagawa, Naomi, Ohtani, Katsuki, Yamamoto, Masaki, Ito, Yushi, Hokosaki, Tatsunori, Kuwahara, Yuta, Masutani, Satoshi, Nomura, Koji, Wada, Tsutomu, Sawada, Hirofumi, Abiko, Masayuki, Takahashi, Tatsunori, Ishikawa, Yuichi, Okada, Seigo, Naitoh, Atsushi, Toda, Takako, Ando, Tatsuya, Masuzawa, Akihiro, Hoshino, Shinsuke, Kawada, Masaaki, Nomura, Yuichi, Ueno, Kentaro, Ohashi, Naoki, Tachibana, Tsuyoshi, Cao, Yuchen, Ueda, Hideaki, Yanagi, Sadamitsu, Koide, Masaaki, Mitsushita, Norie, Higashi, Kouji, Minosaki, Yoshihiro, Hayashi, Tomohiro, Okamoto, Takashi, Kuraishi, Kenji, Ehara, Eiji, Ishida, Hidekazu, Horigome, Hitoshi, Murakami, Takashi, Takei, Kohta, Ishii, Taku, Harada, Gen, Hirata, Yasutaka, Maeda, Jun, Tatebe, Shunsuke, Ota, Chiharu, Hayabuchi, Yasunobu, Sakazaki, Hisanori, Sasaki, Takashi, Hirono, Keiichi, Suzuki, Sayo, Yasuda, Masahiro, Takeda, Atsuhito, Sawai, Madoka, Miyaji, Kagami, Kitagawa, Atsushi, Nakai, Yosuke, Kakimoto, Nobuyuki, Agematsu, Kouta, Manabe, Atsushi, Saiki, Yoshikatsu“…RESULTS: The 5-year, 10-year, 15-year, and 20-year cardiovascular death-free survival rates for all patients were 92.0%, 90.4%, 87.3%, and 86.1%, respectively. …”
Publicado 2023
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486272por Zhao, Jie, He, Yayi, Yang, Xue, Tian, Panwen, Zeng, Liang, Huang, Kun, Zhao, Jing, Zhou, Jiaqi, Zhu, Yin, Wang, Qiyuan, Chen, Mailin, Li, Wen, Gao, Yi, Zhang, Yongchang, Xia, Yang“…After a median follow-up time of 12.1 months, the median progression-free survival (mPFS) was 7.1 (95% CI 6.6 to 7.7) months, whereas the median overall survival (mOS) was not reached. …”
Publicado 2023
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486273por Miao, Xin, Wu, Liviawati S., Lin, Shun Xin Wang, Xu, Yan, Chen, Yang, Iwaki, Yuki, Kobos, Rachel, Stephenson, Tara, Kemmerer, Kristy, Uhlar, Clarissa M., Banerjee, Arnob, Goldberg, Jenna D., Trancucci, Danielle, Apte, Amit, Verona, Raluca, Pei, Lixia, Desai, Rachit, Hickey, Kathleen, Su, Yaming, Ouellet, Daniele, Samtani, Mahesh N., Guo, Yue, Garfall, Alfred L., Krishnan, Amrita, Usmani, Saad Z., Zhou, Honghui, Girgis, Suzette“…Exposure–response analyses were conducted, including overall response rate (ORR), duration of response (DoR), progression-free survival (PFS), overall survival (OS), and the incidence of grade ≥ 3 anemia, neutropenia, lymphopenia, leukopenia, thrombocytopenia, and infection. …”
Publicado 2023
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486274por Lundgren, Christine, Tutzauer, Julia, Church, Sarah E., Stål, Olle, Ekholm, Maria, Forsare, Carina, Nordenskjöld, Bo, Fernö, Mårten, Bendahl, Pär-Ola, Rydén, Lisa“…The median follow-up periods for a recurrence-free interval (RFi) and overall survival (OS) were 28 and 33 years, respectively. …”
Publicado 2023
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486275por Ferrand, Timothy, Boulant, Justine, He, Chloe, Chambost, Jérôme, Jacques, Céline, Pena, Chris-Alexandre, Hickman, Cristina, Reignier, Arnaud, Fréour, Thomas“…C.Hi. has received consulting fees and honoraria from Vitrolife, Merck Serono, Ferring, Cooper Surgical, Dibimed, Apricity, and Fairtility and travel support from Fairtility and Vitrolife, participates on an advisory board for Merck Serono, was the founder and organizer of the AI Fertility conference, has stock in Aria Fertility, TMRW, Fairtility, Apricity, and IVF Professionals, and received free equipment from Planar in exchange for first user feedback. …”
Publicado 2023
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486276por Marler, Jennifer D, Fujii, Craig A, Utley, MacKenzie T, Balbierz, Daniel J, Galanko, Joseph A, Utley, David S“…Participants were offered 12 weeks of free nicotine replacement therapy (NRT). Data were self-reported via a web-based questionnaire with videoconference biovalidation in participants who reported 7-day point-prevalence abstinence (PPA). …”
Publicado 2023
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486277por Tessnow, Alex, Wyne, Kathleen L, Patrick Schneiderman, Chris, Pinsky, Brett, Guo, Dianlin, Barger, Bruce, Antunez Flores, Oscar“…OHT was defined as presence of elevated thyroid-stimulating hormone (TSH >4.0 mIU/L) and a subnormal or low level of free thyroxine (FT4 < 0.8 ng/dL); patients with a documented prescription (Rx) for HT Tx with levothyroxine or liothyronine were also categorized with OHT regardless of lab values. …”
Publicado 2023
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486278por Simeoli, Chiara, Di Paola, Nicola, Stigliano, Antonio, Lardo, Pina, Kearney, Tara, Mezosi, Emese, Ghigo, Ezio, Giordano, Roberta, Mariash, Cary N, Donegan, Diane, Feelders, Richard A, Hand, Austin L, Moraitis, Andreas G, Pivonello, Rosario“…In the surgical study, baseline (BL) mean 24-h urinary free cortisol (UFC) was 615.6 mcg/day (by immunoassay; 2.1x upper limit of normal [ULN]); mean and median time to hemostasis assessment after remission were 6.2 and 6 mos, respectively. …”
Publicado 2023
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486279por De Andrade, Nathalia Liberatoscioli Menezes, de Assis Funari, Mariana Ferreira, Malaquias, Alexsandra, Branco Dantas, Naiara Castelo, Rezende, Raissa, de Polli Cellin, Laurana, Homma, Thais Kataoka, Lerario, Antonio Marcondes, Arnhold, Ivo J, Vasques, Gabriela Andrade, Lima Jorge, Alexander Augusto“…The difficulty to search for candidate genes increases the importance of using a hypothesis-free approach as whole exome sequencing (WES) for these children. …”
Publicado 2023
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486280por Osataphan, Soravis, Vamvini, Maria, Rosen, Evan D, Pei, Lei, Erlikh, Natanie, Singh, Gurcharan, Dhorajiya, Poojaben, Parker, J Anthony, Dreyfuss, Jonathan M, Rattani, Ahmed, Patti, Mary-Elizabeth“…Despite elevated insulin (537 uIU/mL), C-peptide (10.1 ng/mL), and proinsulin (634.0 pmol/L), he remains free of level 3 hypoglycemia. No adverse effects have been observed. …”
Publicado 2023
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