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  1. 486541
    por Earp, Madalene, Tyrer, Jonathan P., Winham, Stacey J., Lin, Hui-Yi, Chornokur, Ganna, Dennis, Joe, Aben, Katja K. H., Anton‐Culver, Hoda, Antonenkova, Natalia, Bandera, Elisa V., Bean, Yukie T., Beckmann, Matthias W., Bjorge, Line, Bogdanova, Natalia, Brinton, Louise A., Brooks-Wilson, Angela, Bruinsma, Fiona, Bunker, Clareann H., Butzow, Ralf, Campbell, Ian G., Carty, Karen, Chang-Claude, Jenny, Cook, Linda S., Cramer, Daniel W, Cunningham, Julie M., Cybulski, Cezary, Dansonka-Mieszkowska, Agnieszka, Despierre, Evelyn, Doherty, Jennifer A., Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Easton, Douglas F., Eccles, Diana M., Edwards, Robert P., Ekici, Arif B., Fasching, Peter A., Fridley, Brooke L., Gentry-Maharaj, Aleksandra, Giles, Graham G., Glasspool, Rosalind, Goodman, Marc T., Gronwald, Jacek, Harter, Philipp, Hein, Alexander, Heitz, Florian, Hildebrandt, Michelle A. T., Hillemanns, Peter, Hogdall, Claus K., Høgdall, Estrid, Hosono, Satoyo, Iversen, Edwin S., Jakubowska, Anna, Jensen, Allan, Ji, Bu-Tian, Jung, Audrey Y., Karlan, Beth Y., Kellar, Melissa, Kiemeney, Lambertus A., Kiong Lim, Boon, Kjaer, Susanne K., Krakstad, Camilla, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Le, Nhu D., Lele, Shashi, Lester, Jenny, Levine, Douglas A., Li, Zheng, Liang, Dong, Lissowska, Jolanta, Lu, Karen, Lubinski, Jan, Lundvall, Lene, Massuger, Leon F. A. G., Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R., McNeish, Iain, Menon, Usha, Milne, Roger L., Modugno, Francesmary, Moysich, Kirsten B., Ness, Roberta B., Nevanlinna, Heli, Odunsi, Kunle, Olson, Sara H., Orlow, Irene, Orsulic, Sandra, Paul, James, Pejovic, Tanja, Pelttari, Liisa M., Permuth, Jenny B., Pike, Malcolm C., Poole, Elizabeth M., Rosen, Barry, Rossing, Mary Anne, Rothstein, Joseph H., Runnebaum, Ingo B., Rzepecka, Iwona K., Schernhammer, Eva, Schwaab, Ira, Shu, Xiao-Ou, Shvetsov, Yurii B., Siddiqui, Nadeem, Sieh, Weiva, Song, Honglin, Southey, Melissa C., Spiewankiewicz, Beata, Sucheston-Campbell, Lara, Tangen, Ingvild L., Teo, Soo-Hwang, Terry, Kathryn L., Thompson, Pamela J., Thomsen, Lotte, Tworoger, Shelley S., van Altena, Anne M., Vergote, Ignace, Vestrheim Thomsen, Liv Cecilie, Vierkant, Robert A., Walsh, Christine S., Wang-Gohrke, Shan, Wentzensen, Nicolas, Whittemore, Alice S., Wicklund, Kristine G., Wilkens, Lynne R., Woo, Yin-Ling, Wu, Anna H., Wu, Xifeng, Xiang, Yong-Bing, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Lee, Alice W, Pearce, Celeste L., Berchuck, Andrew, Schildkraut, Joellen M., Ramus, Susan J., Monteiro, Alvaro N. A., Narod, Steven A., Sellers, Thomas A., Gayther, Simon A., Kelemen, Linda E., Chenevix-Trench, Georgia, Risch, Harvey A., Pharoah, Paul D. P., Goode, Ellen L., Phelan, Catherine M.
    Publicado 2018
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    Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility
  2. 486542
    por Harausz, Elizabeth P., Garcia-Prats, Anthony J., Law, Stephanie, Schaaf, H. Simon, Kredo, Tamara, Seddon, James A., Menzies, Dick, Turkova, Anna, Achar, Jay, Amanullah, Farhana, Barry, Pennan, Becerra, Mercedes, Chan, Edward D., Chan, Pei Chun, Ioana Chiotan, Domnica, Crossa, Aldo, Drobac, Peter C., Fairlie, Lee, Falzon, Dennis, Flood, Jennifer, Gegia, Medea, Hicks, Robert M., Isaakidis, Petros, Kadri, SM, Kampmann, Beate, Madhi, Shabir A., Marais, Else, Mariandyshev, Andrei, Méndez-Echevarría, Ana, Moore, Brittany Kathryn, Nargiza, Parpieva, Ozere, Iveta, Padayatchi, Nesri, ur-Rehman, Saleem-, Rybak, Natasha, Santiago-Garcia, Begoña, Shah, N. Sarita, Sharma, Sangeeta, Shim, Tae Sun, Skrahina, Alena, Soriano-Arandes, Antoni, van den Boom, Martin, van der Werf, Marieke J., van der Werf, Tjip S., Williams, Bhanu, Yablokova, Elena, Yim, Jae-Joon, Furin, Jennifer, Hesseling, Anneke C.
    Publicado 2018
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    Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis
  3. 486543
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    Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial
  4. 486544
    “…STUDY SELECTION: English-language randomized clinical trials with available data that measured overall survival (OS), progression-free survival (PFS), or objective response rate comparing immune checkpoint inhibitors, tumor vaccines, or cellular immunotherapy with conventional therapy for patients with advanced or metastatic NSCLC were included. …”
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    Association of Survival and Immune-Related Biomarkers With Immunotherapy in Patients With Non–Small Cell Lung Cancer: A Meta-analysis and Individual Patient–Level Analysis
  5. 486545
    “…Participants aged 69–71 years received T1 and FLAIR volumetric MRI, florbetapir amyloid-PET imaging, and cognitive assessment at University College London (London, UK); all participants were dementia-free. Blood pressure measurements had been collected at ages 36, 43, 53, 60–64, and 69 years. …”
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    Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study
  6. 486546
    por Ellis, Natalya, Takhar, Gagandeep
    Publicado 2019
    “…Following this episode, she was seen at the Periodic Fever Clinic at the Royal Free, where they confirmed a diagnosis of phenotypical adult-onset Still’s disease, however her genetic testing was negative. …”
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    23. Adult-onset Still’s disease presenting as SLE
  7. 486547
    por Davies, Edward, Hajela, Vijay
    Publicado 2019
    “…Subsequent genetic analysis at the Royal Free hospital for fever syndromes has not found a pre-described genetic polymorphism. …”
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    19. Fever, dyspnoea and a raised CRP: just another chest sepsis?
  8. 486548
    por Chen, Ping, Li, Xiaodong
    Publicado 2019
    “…Background: Exercise therapy has been widely applied in clinical rehabilitation as an important practical and side effect—free adjuvant therapy, with a significant effect in alleviating motor dysfunction of patients with Parkinson’s disease (PD) or animal PD models. …”
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    Study on Effect of Striatal mGluR2/3 in Alleviating Motor Dysfunction in Rat PD Model Treated by Exercise Therapy
  9. 486549
    “…The cost of messages could also be a problem, and many thought that messages should be free of charge (high confidence). Language issues as well as skills in reading, writing, and using mobile phones could also be a problem (moderate confidence). …”
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    Clients’ perceptions and experiences of targeted digital communication accessible via mobile devices for reproductive, maternal, newborn, child, and adolescent health: a qualitative evidence synthesis
  10. 486550
    “…Cases with intra-abdominal free air were excluded. Collected CT imaging data and an additional 149 clinical data elements per patient for a total of 75 PI cases. …”
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    3132 Machine Learning for Prediction of Pathologic Pneumatosis Intestinalis Using CT Scans
  11. 486551
    “…Mice were dosed with 3 nmol/kg/d of targeted-ePTHrP, non-conjugated (free) ePTHrP, or saline. Following a 4-week study, fracture callus densities were measured using microCT. …”
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    3505 Fracture Targeted Parathyroid Hormone Agonist As An Effective Pharmaceutical For Bone Repair in Mouse and Canine Models
  12. 486552
    “…We found that by looking beyond the taken-for-granted features of translational research teams, we are free to discover new ways of organizing research and community engagement that are innovative yet productive. …”
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    2316 The extra-territorial translational team: Advances in multi-faceted community engagement
  13. 486553
    por Sønderby, Ida E, Gústafsson, Ómar, Doan, Nhat Trung, Hibar, Derrek P, Martin-Brevet, Sandra, Abdellaoui, Abdel, Ames, David, Amunts, Katrin, Andersson, Michael, Armstrong, Nicola J, Bernard, Manon, Blackburn, Nicholas, Blangero, John, Boomsma, Dorret I, Bralten, Janita, Brattbak, Hans-Richard, Brodaty, Henry, Brouwer, Rachel M, Bülow, Robin, Calhoun, Vince, Caspers, Svenja, Cavalleri, Gianpiero, Chen, Chi-Hua, Cichon, Sven, Ciufolini, Simone, Corvin, Aiden, Crespo-Facorro, Benedicto, Curran, Joanne E, Dale, Anders M, Dalvie, Shareefa, Dazzan, Paola, de Geus, Eco J C, de Zubicaray, Greig I., de Zwarte, Sonja M. C., Delanty, Norman, den Braber, Anouk, Desrivières, Sylvane, Donohoe, Gary, Draganski, Bogdan, Ehrlich, Stefan, Espeseth, Thomas, Fisher, Simon E, Franke, Barbara, Frouin, Vincent, Fukunaga, Masaki, Gareau, Thomas, Glahn, David C, Grabe, Hans, Groenewold, Nynke A., Haavik, Jan, Håberg, Asta, Hashimoto, Ryota, Hehir-Kwa, Jayne Y, Heinz, Andreas, Hillegers, Manon H. J., Hoffmann, Per, Holleran, Laurena, Hottenga, Jouke-Jan, Hulshoff, Hilleke E, Ikeda, Masashi, Jahanshad, Neda, Jernigan, Terry, Jockwitz, Christiane, Johansson, Stefan, Jonsdottir, Gudrun A, Jönsson, Erik G, Kahn, Rene, Kaufmann, Tobias, Kelly, Sinead, Kikuchi, Masataka, Knowles, Emma E M, Kolskår, Knut K, Kwok, John B, Hellard, Stephanie Le, Leu, Costin, Liu, Jingyu, Lundervold, Astri J, Lundervold, Arvid, Martin, Nicholas G., Mather, Karen, Mathias, Samuel R., McCormack, Mark, McMahon, Katie L., McRae, Allan, Milaneschi, Yuri, Moreau, Clara, Morris, Derek, Mothersill, David, Mühleisen, Thomas W, Murray, Robin, Nordvik, Jan E, Nyberg, Lars, Olde Loohuis, Loes M, Ophoff, Roel, Paus, Tomas, Pausova, Zdenka, Penninx, Brenda, Peralta, Juan M, Pike, Bruce, Prieto, Carlos, Pudas, Sara, Quinlan, Erin, Quintana, Daniel S, Reinbold, Céline S, Marques, Tiago Reis, Reymond, Alexandre, Richard, Genevieve, Rodriguez-Herreros, Borja, Roiz-Santiañez, Roberto, Rokicki, Jarek, Rucker, James, Sachdev, Perminder, Sanders, Anne-Marthe, Sando, Sigrid B, Schmaal, Lianne, Schofield, Peter R, Schork, Andrew J., Schumann, Gunter, Shin, Jean, Shumskaya, Elena, Sisodiya, Sanjay, Steen, Vidar M, Stein, Dan J, Steinberg, Stacy, Strike, Lachlan, Teumer, Alexander, Thalamuthu, Anbu, Tordesillas-Gutierrez, Diana, Turner, Jessica, Ueland, Torill, Uhlmann, Anne, Ulfarsson, Magnus O., van ’t Ent, Dennis, van der Meer, Dennis, van Haren, Neeltje E. M., Vaskinn, Anja, Vassos, Evangelos, Walters, G. Bragi, Wang, Yunpeng, Wen, Wei, Whelan, Christopher D, Wittfeld, Katharina, Wright, Margie, Yamamori, Hidenaga, Zayats, Tetyana, Agartz, Ingrid, Westlye, Lars T, Jacquemont, Sébastien, Djurovic, Srdjan, Stefánsson, Hreinn, Stefánsson, Kári, Thompson, Paul, Andreassen, Ole A.
    Publicado 2018
    “…After stringent CNV calling procedures, and standardized FreeSurfer image analysis, we found negative dose-response associations with copy number on intracranial volume and on regional caudate, pallidum and putamen volumes (β = −0.71 to −1.37; P < 0.0005). …”
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    Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
  14. 486554
    “…Outcomes were determined with a validated ‘Readiness for Interprofessional Learning’ questionnaire, to which we added questions with free comments, combining quantitative and qualitative research methods. …”
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    Interprofessional education in geriatric medicine: towards best practice. A controlled before–after study of medical and nursing students
  15. 486555
    “…A recently developed catheter tracking technique using a real-time single-shot balanced steady-state free precession (bSSFP), flip angle (FA) 35–45°, echo time (TE) 1.3 ms, repetition time (TR) 2.7 ms, 40° partial saturation (pSAT) pre-pulse was used to visualize the gadolinium-filled balloon, MR-conditional guidewire, and cardiac structures simultaneously. …”
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    Invasive cardiovascular magnetic resonance (iCMR) for diagnostic right and left heart catheterization using an MR-conditional guidewire and passive visualization in congenital heart disease
  16. 486556
    “…One study assessed the maximum rash‐free period but provided insufficient data for analysis. …”
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    Topical antifungals for seborrhoeic dermatitis
  17. 486557
    por Pfeffer, Daniel A., Ley, Benedikt, Howes, Rosalind E., Adu, Patrick, Alam, Mohammad Shafiul, Bansil, Pooja, Boum, Yap, Brito, Marcelo, Charoenkwan, Pimlak, Clements, Archie, Cui, Liwang, Deng, Zeshuai, Egesie, Ochaka Julie, Espino, Fe Esperanza, von Fricken, Michael E., Hamid, Muzamil Mahdi Abdel, He, Yongshu, Henriques, Gisela, Khan, Wasif Ali, Khim, Nimol, Kim, Saorin, Lacerda, Marcus, Lon, Chanthap, Mekuria, Asrat Hailu, Menard, Didier, Monteiro, Wuelton, Nosten, François, Oo, Nwe Nwe, Pal, Sampa, Palasuwan, Duangdao, Parikh, Sunil, Pitaloka Pasaribu, Ayodhia, Poespoprodjo, Jeanne Rini, Price, David J., Roca-Feltrer, Arantxa, Roh, Michelle E., Saunders, David L., Spring, Michele D., Sutanto, Inge, Ley-Thriemer, Kamala, Weppelmann, Thomas A., von Seidlein, Lorenz, Satyagraha, Ari Winasti, Bancone, Germana, Domingo, Gonzalo J., Price, Ric N.
    Publicado 2020
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    Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis
  18. 486558
    Publicado 2019
    “…The median follow-up time was 42 (3–110) months. ②The 5-year progression-free survival (PFS) for R-CHOP group, dose-intensive chemotherapy group and auto-HSCT group were (33.5±10.7) %, (55.3±10.1) % and (65.8±13.6) % (P=0.012), the 5-year overall survival (OS) were (49.7±9.0) %, (61.6±10.2) % and (78.6±7.8) % (P=0.035), respectively. …”
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    诱导化疗联合或不联合自体造血干细胞移植治疗年龄≤60岁初治中高危/高危弥漫大B细胞淋巴瘤的比较研究
  19. 486559
    “…Blood biochemical parameters showed that Broiler chickens fed on the SP2 diet had higher levels of total protein (TP) (p ≤ 0.05), albumin (ALB) (p ≤ 0.05), creatinine (CRE) (p ≤ 0.05), and aspartate aminotransferase (AST) (p ≤ 0.05) and, lower level of uric acid (UA) (p ≤ 0.05), blood urea nitrogen (BUN) (p ≤ 0.05), glucose (GLU) (p ≤ 0.05), and alanine aminotransferase (ALT) (p ≤ 0.05) in the starter phase; however, higher level of TP (p ≤ 0.05), GLU (p ≤ 0.05), CRE (p ≤ 0.05), and AST (p ≤ 0.05), and lower level of ALB (p ≤ 0.05), UA (p ≤ 0.05), and ALT (p ≤ 0.05) in the grower phase; RPGC had higher level of TP (p ≤ 0.05), UA (p ≤ 0.05), GLU (p ≤ 0.05), ALT (p ≤ 0.05) and AST (p ≤ 0.05), and lower level of ALB (p ≤ 0.05), BUN (p ≤ 0.05), and CRE (p ≤ 0.05) in the starter phase; however, in grower phase, RPGC had higher level of TP (p ≤ 0.05), and ALB (p ≤ 0.05), and lower level of UA (p ≤ 0.05), CRE (p ≤ 0.05), ALT (p ≤ 0.05), and AST (p ≤ 0.05). Free amino acids profile showed that broiler fed on standard protein diet SP2 had reduced the methionine (p ≤ 0.05) concentration; RPC increased the concentrations of taurine (p ≤ 0.05), phosphoethanolamine (p ≤ 0.05), threonine (p ≤ 0.05), valine (p ≤ 0.05), isoleucine (p ≤ 0.05), phenylalanine (p ≤ 0.05), ornithine (p ≤ 0.05), and lysine (p ≤ 0.05) and reduced the citrulline (p ≤ 0.05) concentration; RPG increased the concentration of glutamate (p ≤ 0.05), glycine (p ≤ 0.05), cysteine (p ≤ 0.05), and arginine (p ≤ 0.05), and decreased the concentration of tyrosine (p ≤ 0.05); and RPGC increased the concentration of serine (p ≤ 0.05) and reduced the concentration of hydroxyproline (p ≤ 0.05). …”
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    The Response of Broiler Chickens to Dietary Soybean Meal Reduction with Glycine and Cysteine Inclusion at Marginal Sulfur Amino Acids (SAA) Deficiency
  20. 486560
    Publicado 2020
    “…Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. …”
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    Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019
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