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521“…Enzymes which catalyze the formation of free radicals in vitro will catalyze similar reactions in vivo. …”
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522“…The B2 subunit contains an antiferromagnetically coupled pair of ferric ions and a stable tyrosyl free radical. EPR studies show that the tyrosyl radical, formed by loss of ferric ions and a stable tyrosyl free radical. …”
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526Publicado 1988“…In the study reported here, we examine microtubule dynamics within the centrosome-free fragments and find that, after severing, microtubule reorganization is initiated at the proximal (cut) end of an arm and migrates distally with the aggregated pigment mass until it becomes permanently positioned at the middle of the arm. …”
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527“…The electrophoretic fractions of serum proteins were studied up to the 5th generation in a colony of germ-free rats. The germ-free animals had significantly lower concentrations of beta and the gamma globulins, while the other fractions were within normal limits. …”
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531“…A flow injection analyser has been constructed to allow an operator-free determination of up to 40 samples. Besides the usual FIA apparatus, the analyser includes a home-made sample introduction device made with three electromechanical three-way valves and an auto-sampler from Technicon which has been adapted to be commanded by an external digital signal. …”
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532por Aon, Miguel A., Roussel, Marc R., Cortassa, Sonia, O'Rourke, Brian, Murray, Douglas B., Beckmann, Manfred, Lloyd, David“…Therefore we conclude that in S. cerevisiae and cardiomyocytes the dynamics are scale-free in vivo. Applying RDA and PSA to data generated from an in silico model of mitochondrial function indicated that in yeast and cardiomyocytes the underlying mechanisms regulating the scale-free behavior are similar. …”
Publicado 2008
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533por Kaufmann, Michael“…An indispensable thermodynamic prerequisite for such a primordial anabolism is the mechanistic coupling to processes that supplied the free energy required. Here I review different sources of free energy and discuss the potential of each form having been involved in the very first anabolic reactions that were fundamental to increase molecular complexity and thus were essential for life.…”
Publicado 2009
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534“…Physiological alteration and pathological states produced by free radicals depend on disequilibrium between free radical production and antioxidant levels leading to oxidative stress. …”
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537“…However, it is not known whether the antioxidant actions of dexrazoxane are totally dependent on its metabolization to its rings-opened hydrolysis product and whether dexrazoxane has any effect on the iron-independent oxygen free radical production. In this study, we examined the scavenging effect of dexrazoxane on hydroxyl, superoxide, lipid, DPPH and ABTS(+) free radicals in vitro solution systems. …”
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538por Meynen, Gerben“…As it turns out, philosophers of free will frequently refer to mental disorders as conditions that compromise free will and reduce moral responsibility. …”
Publicado 2010
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539“…Moreover, hepcidin controls ferroportin and plays a central role in the iron metabolism. Excess “free” reactive iron produces damaging free radicals via Fenton or Harber-Weiss reactions. …”
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