“…Finally, most mutations of concern are either in or in the vicinity of high local topological free energy conformations, suggesting that high local topological free energy conformations could be targets for mutations with significant impact of protein function. …”
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“…To solve the problem, this paper proposes a model-free stereo calibration method for binocular fisheye camera based on neural-network. …”
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“…Here we engineer a fatigue-free yet fully healable hybrid ionic skin toughened by a high-energy, self-healable elastic nanomesh, resembling the repairable nanofibrous interwoven structure of human skin. …”
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“…OBJECTIVE: To compare fatigue and its subtypes between adolescents with chronic MSK pain and pain-free controls and to test if fatigue subtypes were associated with concurrent pain and its impact (pain intensity, number of pain sites, pain interference, and functional disability) or experimental pain (intensity and tolerance) in adolescents with chronic MSK pain. …”
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“…Single-cell suspensions enriched for undifferentiated spermatogonia from pre-pubertal bucks were seeded on laminin-coated tissue culture plates and maintained in a commercial media based on serum-free composition. The serum-free media was conditioned on goat fetal fibroblasts and supplemented with a growth factor cocktail that included glial cell line-derived neurotrophic factor (GDNF), leukemia inhibitory factor (LIF), stromal cell-derived factor (SDF), and fibroblast growth factor (FGF) before use. …”
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“…Here, we report that femtosecond time-resolved pump-probe microscopy could provide label-free and chemical-specific detection of melanin species in human UM based on their distinct transient relaxation dynamics at the subpicosecond timescale. …”
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“…Aim: The Cass Clinic is a student-run free clinic in Detroit, Michigan that treats chronic diseases including hypertension (HTN), diabetes mellitus (DM), and obesity. …”
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“…Carotid free-floating thrombus (FFT) is very rarely diagnosed in patients with acute ischemic stroke. …”
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“…For laying hens, it is more challenging under cage-free conditions comparing to caged systems. In this study, we developed a deep learning model (YOLOv5x-hens) to monitor hens’ behaviors in cage-free facilities. …”
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“…SIMPLE SUMMARY: Monitoring diseases and lesions in free-ranging and captive wild animals is important for biodiversity conservation and for understanding factors that can impact not only animal health but also human and environmental health. …”
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“…The strategies in the present study are ready to be incorporated into field collections in free-roaming bison herds.…”
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“…Signal strength difference (DIFF), a calibration-free solution for handling the received signal strength variance between diverse devices, can effectively reduce the negative impact of signal fluctuation. …”
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“…Historically, studies have aimed at the detection of specific mutations on cell-free DNA (cfDNA), but recently, the study of cell-free RNA (cfRNA) has gained traction. …”
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“…Formaldehyde-free hair-straightening products are hair-smoothening solutions widely used by professional beauty salons. …”
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“…However, the deployment of reference objects or ground control points (GCPs) for velocity calibration is still a challenge for in situ free-surface velocity measurements. By combining space-time image velocimetry (STIV) with direct sensor orientation (DSO) photogrammetry, a laser distance meter (LDM)-supported photogrammetric device is designed, to realize the GCPs-free surface velocity measurement under an oblique shooting angle. …”
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