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341“…The present study aimed to investigate the influence of circular RNA nuclear receptor-interacting protein 1 (circNRIP1) on the chemotherapeutic effect of 5-fluorouracil (5-FU) in colorectal cancer (CRC) and reveal its potential molecular mechanisms. …”
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342por Zarghami Dehaghani, Maryam, Yousefi, Farrokh, Sajadi, S. Mohammad, Tajammal Munir, Muhammad, Abida, Otman, Habibzadeh, Sajjad, Mashhadzadeh, Amin Hamed, Rabiee, Navid, Mostafavi, Ebrahim, Saeb, Mohammad Reza“…Methods: First, interactions parameters of the atoms of 5-FU were quantified from the DREIDING force field. …”
Publicado 2021
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343por Zeng, Di, Wang, Yaping, Chen, Yi, Li, Danyang, Li, Guoli, Xiao, Hanxianzhi, Hou, Jiyin, Wang, Ziling, Hu, Ling, Wang, Lu, Li, Jing“…Oxidative stress induced by chemotherapeutic agents causes hepatotoxicity. 5-Fluorouracil (5-FU) has been found to have a variety of side effects, but its toxic effect on the liver and the mechanism are still unclear. …”
Publicado 2021
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345por Zhang, Xuan, Li, Qing, Du, Aibei, Li, Yifei, Shi, Qing, Chen, Yanrong, Zhao, Yang, Wang, Bin, Pan, Feng“…The development of resistance to 5-fluorouracil (5FU) chemotherapy is a major handicap for sustained effective treatment in peritoneal carcinomatosis (PC) of colorectal cancer (CRC). …”
Publicado 2021
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346por Nivethaa, E. A. K., Dhanavel, S., Narayanan, V., Narayana Kalkura, S., Sivasankari, J., Sivanandham, N., Stephen, A.“…The prepared sample has been characterized using various techniques that confirm the formation of the nanocomposite, encapsulation of 5-FU into the nanocomposite, the structure of 5-FU and Au in the nanocomposite and the formation of the polymer matrix nanocomposite. …”
Publicado 2021
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347por Wu, Yuanjing, Li, Qianyun, Zheng, Hanqing, Luo, Shijie, Liu, Qunyue, Yan, Zhao, Huang, QitangEnlace del recurso
Publicado 2022
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348por Liu, Tian-Tian, Liu, Xiao-Tian, Huang, Gui-Li, Liu, Long, Chen, Qing-Xi, Wang, Qin“…In this study, lipase inhibitor Fu Brick Theophylline (FBT) was screened based on enzyme molecular dynamics, and the inhibition mechanism of lipase inhibitors on obesity was analyzed and discussed at the cellular level and animal model level. …”
Publicado 2022
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349por Xuexue, Zheng, Xin, Hong, Youlan, Jin, Chao, Wang, Zhonghua, Liu, Jianan, Huang, Qin, Li“…Floral-fungal aroma type, ripe-fungal aroma type and fresh-fungal aroma type were the main aroma types of Fu brick tea by QDA. A total of 112 volatile compounds were identified and quantified in tea samples by HS-SPME/GC–MS analysis. …”
Publicado 2022
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350por Ajalli, Narges, Pourmadadi, Mehrab, Yazdian, Fatemeh, Rashedi, Hamid, Navaei-Nigjeh, Mona, Díez-Pascual, Ana M.“…In the present work, an intelligent nano-system consisting of Chitosan (Ch)/Gamma alumina (γAl)/Fe(3)O(4) and 5-Fluorouracil (5-FU) was synthesized and designed for the first time in order to influence the Michigan Cancer Foundation-7 (MCF-7) cell line in the treatment of breast cancer. …”
Publicado 2022
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351“…(Ser878Arg)) with unknown significance was discovered in the whole exome; pathogenic MBTPS1 variants cause the autosomal recessive Kondo-Fu type of spondyloepiphyseal dysplasia (SEDKF, OMIM®: 618392). …”
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352“…Next, in a tumor-bearing nude mouse model, HCT116 was chosen as the sensitive cell line, and 5-fluorouracil (5-Fu) was chosen as the positive medicine. It was noteworthy that both 2′-FL group (2.41 ± 0.57 g) and 2′FL/5-Fu group (1.22 ± 0.35 g) had a significantly lower tumor weight compared with the control (3.87 ± 0.79 g), suggesting 2′-FL could inhibit colon cancer. …”
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353por Shen, Yao, Zhao, Pan, Dong, Kewei, Wang, Jiajia, Li, Huichen, Li, Mengyang, Li, Ruikai, Chen, Suning, Shen, Yuxia, Liu, Zhiyu, Xie, Mianjiao, Shen, Peng, Zhang, Jian“…Finally, the efficacy of combined treatment of tadalafil and 5-FU was verified. RESULTS: PRMT5 was highly expressed in colorectal cancer tissues compared with their normal counterparts and correlated with poor prognosis in CRC patients. …”
Publicado 2022
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354por Ndemazie, Nkafu Bechem, Inkoom, Andriana, Ebesoh, Dexter, Bulusu, Raviteja, Frimpong, Esther, Trevino, Jose, Han, Bo, Zhu, Xue, Agyare, Edward“…Objective: The main aim was to synthesize, characterize and evaluate the anticancer activity of 1,3-bistetrahydrofuran-2yl-5FU (MFU). Methods: MFU was synthesized by using 5-fluorouracil (5-FU) and tetrahydrofuran acetate, and characterized by nuclear magnetic resonance (NMR), micro-elemental analysis, high-performance liquid chromatography (HPLC), and liquid chromatography with mass spectrophotometry (LC-MS). …”
Publicado 2022
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355por Arjmandi, Khadijeh, Ameli, Fereshteh, Salahshourifar, Iman, Esfandbod, Mohsen, Irani, Shiva“…OBJECTIVE: Neoadjuvant chemotherapy with 5-fluorouracil (5FU) is one of the most effective treatment options for gastric cancer patients. …”
Publicado 2022
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356por Hwang, Ga-Ram, Yuen, John G., Fesler, Andrew, Farley, Hannah, Haley, John D., Ju, Jingfang“…In this study, we investigated the therapeutic potential of miR-129 modified with 5-fluorouracil (5-FU) in NSCLC. Our results show that 5-FU modified miR-129 (5-FU-miR-129) inhibits proliferation, induces apoptosis, and retains function as an miRNA in NSCLC cell lines A549 and Calu-1. …”
Publicado 2023
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359por Chaigneau, Thomas, Aguilera Munoz, Lina, Oger, Caroline, Gourdeau, Clémence, Hentic, Olivia, Laurent, Lucie, Muller, Nelly, Dioguardi Burgio, Marco, Gagaille, Marie-Pauline, Lévy, Philippe, Rebours, Vinciane, Hammel, Pascal, de Mestier, Louis“…OBJECTIVES: We aimed to report the efficacy and safety of the leucovorin and 5-fluorouracil (LV5FU2) and carboplatin combination in this setting. …”
Publicado 2023
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360“…SNHG6 silencing markedly promoted 5-FU-mediated suppression on KYSE150 and KYSE450 cells. …”
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