“…METHODS: Longitudinal data (follow-up wave 7–9) were taken from the multicenter prospective cohort “Study on needs, health service use, costs, and health-related quality of life in a large sample of oldest-old primary care patients (85+)” (AgeQualiDe), covering primary care patients ≥ 85 years (FU7 n = 741, mean age 88.9 years (SD 2.9; 85–100)). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Neutrality tests of Pfs25 variations showed significant negative values of Tajima’s D (-2.15, p<0.01) and Fu’s F (-10.91, p<0.001) statistics tests. Three loci pairs (123, 372), (364, 428) and (390, 394) were detected to be under linkage disequilibrium and none had history of recombination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…FR+ CTC level [≥12.6 folate units (FU)/3 ml, hazard ratio (HR) = 6.957, p = 0.005] and CA19-9 (>34 ng/ml, HR = 3.855, p = 0.037) were independent prognostic factors in multivariate analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Based on different chemotherapy schemes, they were assigned to an observation (Obs) group (DDP + GEM, n = 55) and a control (Con) group [DDP + FU (fluorouracil), n = 45]. The two groups were compared regarding the following items: therapeutic efficacy; serum levels of platelet-derived growth factor-BB (PDGF-BB), soluble epithelial cadherin (SE-CAD), and inflammation-related factors before and after treatment; toxic and side effects; 1-year survival rate; and quality of life (QOL) 6 months after treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To differentiate cytostatic from cytotoxic effects, LDH cytotoxicity was performed, with 5-fluorouracil (5-FU) as positive control. In screening for metastatic potential, scratch wound assay was done, with percent gap closure as indicator of cell migration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…NHT consists of four herbs: Crataegus pinnatifida (Shan Zha), Triticum aestivum (Fu Xiao Mai), Lilium brownii (Baihe), and the fruit of Ziziphus jujuba (Da Zao). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, knockout of MUC3A significantly inhibited invasion ability and enhanced the sensitivity to the chemotherapeutic agent 5-FU. Furthermore, we found that knockout of MUC3A repressed the PI3K/Akt/mTOR pathway through RNA-seq. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Sensitivity of the organoids to chemotherapeutic drugs and tyrosine kinase inhibitors included: 5-FU (IC(50) 43.95 μM), Oxaliplatin (IC(50) 23.49 μM), SN38 (IC(50) 1.02 μM), Apatinib (IC(50) 0.10 μM), Dasatinib (IC(50) 2.27 μM), Docetaxel (IC(50) 5.26 μM), Regorafenib (IC(50) 18.90 μM), and Everolimus (IC(50) 9.20 μM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Addition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival and served as the first line adjuvant chemotherapy in advanced colorectal cancer (CRC) patients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Their diagnoses and treatments followed routine protocols in Fu-Xing Hospital affiliated to Capital Medical University, Beijing, China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The design included a one-session treatment intervention with pre, post, 1-month, and 6-month follow-up (FU) measurements. This treatment session used a “Blind 2 Therapist” EMDR therapy scripted protocol as videoconference psychotherapy that involves non-disclosure of traumatic memory. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…When curative resection is not possible, palliative systemic chemotherapy with gemcitabine and platinum derivate as first line followed by a 5-FU doublet combination as second line is the standard therapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After IC-PCE, 26 patients received concurrent cisplatin and radiotherapy (CDDP-RT), one received concurrent carboplatin/5-fluorouracil and radiotherapy (CBDCA/5-FU-RT), and two received RT alone. The % completion of CDDP-RT was 88.5%. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The star-like shape of the median joining haplotype network, a unimodal mismatch distribution, and significant negative values for Tajima’s D and Fu’s F(S) tests indicated that populations had undergone recent expansion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, these cell lines were treated with chemotherapeutic agents (cisplatin or 5-FU) and SDF-1α, alone or in combination. Our in vitro study results showed SDF-1α promoted the proliferation of tumor cells and overcame the cytotoxic effect of chemotherapy (p < 0.001). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Carboplatin has previously been used in combination with 5-Fluoro uracil (5-FU) or gemcitabine for the treatment of various carcinomas. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The core medicinal materials consisted of Astragalus mongholicus Bunge and Crataegus pinnatifida Bunge, and the core formulae were Bu-Yang-Huan-Wu-Tang and Xie-Fu-Zhu-Yu-Tang. In addition, 7 groups of folk misused medicinal materials were found. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Subconjunctival injection conditions included: no injection, balanced salt solution (BSS), VEGFC, 5-fluorouracil (5FU) and two concentrations of mitomycin-C (MMC). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…He underwent concurrent chemoradiation therapy (CCRT) with cisplatin (30 mg/m(2)) and 5- fluorouracil (5-FU, 500 mg/m(2)) plus IGRT with 70 Gy in 35 fractions for 7 weeks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SEC6‐based risk stratification indicated that 5‐FU treatment was beneficial for low‐risk patients, whereas only aggressive treatments (FOLFOX and FOLFIRI) provided benefits to high‐risk patients in stages II and III. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso