“…In this trial, they compared standard 5FU-chemoradiotherapy (CRT) and radiotherapy with a simultaneous integrated boost (SIB) without concomitant chemotherapy in a non-inferiority design. …”
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“…Two hundred to 2500 hair follicular units were extracted, with an average recipient area of 22.7 cm(2), an average hair follicle unit density of 55.3 ± 9.1 per cm(2), and an average hair/follicular unit (hair/FU) ratio of 1.75 ± 0.07. Thirteen children in this group were followed up for 6–12 months with the following treatment options: FUE (follicular unit extraction, 9 cases), FUT (follicular unit transplantation, 3 cases), and FUT combined with FUE (1 case). …”
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“…Overall survival is favorable for patients who show metabolic response to 5-FU based chemotherapy and continue this during chemoradiation ABSTRACT: Background: Neoadjuvant chemoradiation with esophagectomy is standard management for locally advanced esophageal adenocarcinoma. …”
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“…The stem-related revision rate for any cause at the final FU was 1.7%, due to PJI. No patients underwent stem revision surgery for aseptic loosening. …”
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“…These findings demonstrate that HDAC2 and ATM modulate the responses of colorectal cancer cells towards 5-FU. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10565-022-09731-3.…”
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“…New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis methods (microwave-assisted and grinding techniques). 4,6-Diamino-1,3-diphenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile (2) shows high anti-cancer activity against both HepG2 and HCT-116 with IC(50) of 9.2 ± 2.8 and 7.7 ± 1.8 µM, respectively, which referenced to 5-Fu which is showing activity of 7.86 ± 0.5 and 5.35 ± 0.3 against both HepG2 and HCT-116, respectively. …”
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“…Significant patients had co-morbidities (15.4%) and complications (13.3%). Fluorouracil (5-FU)-based regimens were given to more than half (56%) of the patients. …”
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“…Primary end-point was infection control with a minimum FU of 12 months and according to internationally accepted criteria. …”
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“…Isobologram analysis of cytotoxicity data obtained suggests that the combination of titanocene dichloride and 5-fluorouracil (5-FU) is synergistic. The potent in vivo anti-tumour activity of this compound, supported by the encouraging results from two phase I clinical trials, suggests that titanocene dichloride could be a promising novel chemotherapeutic agent. …”
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“…The aim of this systematic review was to compare the following: (i) chemoradiation followed by chemotherapy (combined modality therapy) vs best supportive care (ii) radiotherapy vs chemoradiation (iii) radiotherapy vs combined modality therapy (iv) chemotherapy vs combined modality therapy (v) 5FU-based combined modality treatment vs another-agent-based combined modality therapy. …”
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“…MIA PaCa2, CFPAC-1 and Capan-1 pancreatic cancer cell lines were treated with GEM, fluouracil (5-FU), docetaxel (DCT), oxaliplatin (OXP), irinotecan (CPT-11), pemetrexed (PMX) and raltitrexed (RTX) as single agent. …”
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“…Given its ease of administration compared with combinations of oxaliplatin with 5-FU/LV, it represents a good therapeutic option in the elderly.…”
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“…NU3076 also caused a significant potentiation of FU cytotoxicity in L1210 cells. These studies demonstrate that nucleoside transport inhibition can be maintained in the absence of AGP binding with the dipyridamole pharmacophore and that such analogues can enhance the cytotoxicity of TS inhibitors. © 1999 Cancer Research Campaign…”
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“…It consisted of eight push injections, given over a 48-h period, of the following drug combination: cisplatin 8.5 mg m(–2), 5-FU 275 mg m(–2), methotrexate 27.5 mg m(–2), mitomycin C 1.2 mg m(–2), and bleomycin 4 mg m(–2). …”
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“…From April 1999 through December 2002, 30 patients with inoperable CBT were treated with gemcitabine 800 mg m(−2), intravenous infusion for 30 min, followed by 5-FU, 2000 mg m(−2) and leucovorin, 300 mg m(−2), intravenous infusion for 24 h, on day 1, 8 and 15, every 4 weeks. …”
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“…Zn(II)PPIX was unable to potentiate antitumor effects of 5-fluorouracil, cisplatin or doxorubicin in three different tumor models, but significantly potentiated toxicity of 5-FU and cisplatin. CONCLUSION: Inhibition of HO-1 exerts antitumor effects but should not be used to potentiate antitumor effects of cancer chemotherapeutics unless procedures of selective tumor targeting of HO-1 inhibitors are developed.…”
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“…In Colo205 cells, combinations of PEP005 with several cytotoxic agents including oxaliplatin, SN38, 5FU, gemcitabine, doxorubicin, vinorelbine, and docetaxel yielded sequence-dependent antiproliferative effects. …”
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“…All patients receive adjuvant chemotherapy (12 weeks continuous infusional 5-FU) and are followed up for 5 years. TME-quality is independently documented by the surgeon and the pathologist. …”
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“…Analyses using Tajima's D, Fu and Li's D* and F* tests indicated a non-neutral pattern of nucleotide variation in all fig wasps. …”
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“…RESULTS: Neutrality tests with Tajima’s D, Fu and Li’s D* and F*, and Fay and Wu’s H indicated possible roles of positive selection on the entire CYP3A locus in non-Africans. …”
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