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561por Genc, Sidika, Taghizadehghalehjoughi, Ali, Yeni, Yesim, Jafarizad, Abbas, Hacimuftuoglu, Ahmet, Nikitovic, Dragana, Docea, Anca Oana, Mezhuev, Yaroslav, Tsatsakis, Aristidis“…Caco-2 colon cancer cells were treated during two different periods (24 and 72 h) with Fe(3)O(4) NPs (6 μg/mL), various concentrations of 5-FU (4–16 μg/mL), and Fe(3)O(4) NPs in combination with 5-FU (4–16 μg/mL) (Fe(3)O(4) NPs + 5-FU). (3) Results: The MTT assay showed that treating the cells with Fe(3)O(4) NPs + 5-FU at 16 µg/mL for 24 or 72 h decreased cell viability and increased their LDH release (p < 0.05 and p < 0.01, respectively). …”
Publicado 2023
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562por Umeki, Yusuke, Matsuoka, Hiroshi, Fujita, Masahiro, Goto, Ai, Serizawa, Akiko, Nakamura, Kenichi, Akimoto, Shingo, Nakauchi, Masaya, Tanaka, Tsuyoshi, Shibasaki, Susumu, Inaba, Kazuki, Uyama, Ichiro, Suda, Koichi“…METHODS: In this single-center study, patient background and treatment outcomes (NAC efficacy assessment, NAC adverse events, short-term postoperative outcomes, and one-year postoperative outcomes) in patients treated with preoperative DCF and preoperative cisplatin+5-FU (CF) were compared retrospectively. PATIENTS: Seventeen patients diagnosed with esophageal squamous cell carcinoma (ESCC) and treated with preoperative DCF therapy and 50 patients treated with preoperative CF therapy between January 2013 and July 2019 were included in this study. …”
Publicado 2023
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563“…Abies ernestii var. salouenensis (Bordères & Gaussen) W. C. Cheng & L. K. Fu is endemic to southwest China, including the southeastern Tibetan Plateau and the northwestern Yunnan Province. …”
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564por Kizilbash, Sani, Jaeckle, Kurt, Mrugala, Maciej, Allred, Jacob, Reid, Joel, Zhong, Wei, Burns, Terry, Giannini, Caterina, Sarkaria, Jann, Adjei, Alex“…WSD0922-Fu therapy will be resumed after post-operative recovery. …”
Publicado 2023
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565por Atzpodien, J, Kirchner, H, Illiger, H J, Metzner, B, Ukena, D, Schott, H, Funke, P J, Gramatzki, M, Jürgenson, S von, Wandert, T, Patzelt, T, Reitz, MEnlace del recurso
Publicado 2001
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566“…BCKGROUND: A number of studies have investigated whether the activity levels of enzymes involved in 5-fluorouracil (5-FU) metabolism are prognostic factors for survival in patients with colorectal carcinoma. …”
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567por Wang, Bi-Dar, Kline, Christina Leah B, Pastor, Danielle M, Olson, Thomas L, Frank, Bryan, Luu, Truong, Sharma, Arun K, Robertson, Gavin, Weirauch, Matthew T, Patierno, Steven R, Stuart, Joshua M, Irby, Rosalyn B, Lee, Norman H“…Treating Par-4-overexpressing HT29 cells with a miR-34a antagomir functionally reversed both BCL2 down-regulation and apoptosis by 5-FU. Conversely, bypassing Par-4 overexpression by direct knockdown of DROSHA expression in native HT29 cells increased miR-34a expression and 5-FU sensitivity. …”
Publicado 2010
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568por Sulzyc-Bielicka, Violetta, Domagala, Pawel, Urasinska, Elzbieta, Bielicki, Dariusz, Safranow, Krzysztof, Domagala, Wenancjusz“…Expression of p21(WAF1) in colorectal tumor cells identifies a subgroup of Astler–Coller stage B2 patients who could benefit significantly from 5FU-based chemotherapy and may improve the selection of patients for adjuvant chemotherapy.…”
Publicado 2011
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569“…BACKGROUND: Despite genetic polymorphism in response to platinum/5-Fu chemotherapy in gastric cancer (GC) has been studied, data reported so far are conflicting and critical consideration is needed before translation to the treatment of GC. …”
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570por de la Cueva, Ana, Ramírez de Molina, Ana, Álvarez-Ayerza, Néstor, Ramos, Ma Angeles, Cebrián, Arancha, del Pulgar, Teresa Gómez, Lacal, Juan Carlos“…BACKGROUND: Colorectal cancer (CRC) is the third major cause of cancer related deaths in the world. 5-fluorouracil (5-FU) is widely used for the treatment of colorectal cancer but as a single-agent renders low response rates. …”
Publicado 2013
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571“…CONCLUSION: The mRNA expression of ERCC1 and TS were not applicable to predict the DFS of Chinese stage II-III CRC patients receiving 5-FU and oxaliplatin based adjuvant chemotherapy.…”
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572por Zhang, Guohua, Yang, Guang, Deng, Yan, Zhao, Xiangling, Yang, Yingbao, Rao, Jinjun, Wang, Wenya, Liu, Xin, He, Jian, Lv, Lin“…BACKGROUND: Xue-Fu-Zhu-Yu decoction (XFZYD), Tian-Ma-Gou-Teng-Yin (TMGTY) and Wen-Dan decoction (WDD) are Chinese herbal formulas used to treat hypertension and cardiovascular diseases in traditional Chinese medicine (TCM). …”
Publicado 2016
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573por Zhou, Mingyi, Yu, Ping, Hou, Kezuo, Fu, Lingyu, Chen, Ying, Qu, Jinglei, Qu, Xiujuan, Liu, Yunpeng, Zhang, Jingdong“…PURPOSE: To investigate the effect of RAS on anti-EGFR moAb + 5-FU infusion based chemotherapy in first-line treatment of mCRC. …”
Publicado 2016
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574por Russo, Annapina, Saide, Assunta, Cagliani, Roberta, Cantile, Monica, Botti, Gerardo, Russo, Giulia“…5-FU is a chemotherapy drug commonly used for the treatment of human cancers; however drug resistance represents a major challenge for its clinical application. …”
Publicado 2016
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575por Tan, Shu-Qiu, Geng, Xue, Liu, Jorn-Hon, Pan, Wynn Hwai-Tzong, Wang, Li-Xiang, Liu, Hui-Kang, Hu, Lei, Chao, Hsiao-Ming“…This study investigates the protective effects and mechanisms of Xue-Fu-Zhu-Yu decoction (XFZYD) with respect to retinal ischemia. …”
Publicado 2017
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576por Kang, Xin, Liang, Zhengkai, Lu, Xiaoguang, Zhan, Libin, Song, Jianbo, Wang, Yi, Yang, Yilun, Fan, Zhiwei, Bai, Lizhi“…OBJECTIVE: The aim of the present study was to examine whether Dai-Huang-Fu-Zi-Tang (DHFZT) could regulate mitochondrial permeability transition pore (MPTP) of intestinal mucosa epithelial cells for alleviating intestinal injury associated with severe acute pancreatitis (SAP). …”
Publicado 2017
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577por Tang, Cheng, Yu, Shan, Jiang, Huiqin, Li, Wei, Xu, Xiaojing, Cheng, Xi, Peng, Ke, Chen, Erbao, Cui, Yuehong, Liu, Tianshu“…5-fluorouracil (5-Fu) metabolism associated enzyme, methylenetetrahydrofolate reductase (MTHFR)'s polymorphism C677T can affect enzyme activity and a series of studies have been performed to examine the association of this MTHFR polymorphism with the clinical outcomes of gastric cancer (GC) patients treated with 5-Fu based chemotherapies. …”
Publicado 2018
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578por Orecchioni, Stefania, Talarico, Giovanna, Labanca, Valentina, Calleri, Angelica, Mancuso, Patrizia, Bertolini, Francesco“…Cyclophosphamide (at low doses) and 5-FU (at medium doses) slightly increased circulating Tregs. …”
Publicado 2018
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579“…The results demonstrated that VNIR-SWIR-FuSI could achieve the best accuracies on both full bands (97.3%) and SPA bands (93.2%). …”
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580“…TLX3 over-expression inhibited HCC cell viability, proliferation, migration, invasion and enhanced 5-FU treatment, whereas silencing TLX3 produced the opposite results. …”
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