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661por Roviello, Giandomenico, Petrioli, Roberto, Nardone, Valerio, Rosellini, Pietro, Multari, Andrea Giovanni, Conca, Raffaele, Aieta, MicheleEnlace del recurso
Publicado 2018
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662por Zhang, Yu, Zhang, Ling, Zhang, Yan, Fan, Xiaoxue, Yang, Weiwei, Yu, Boyang, Kou, Junping, Li, Fang“…The YiQiFuMai powder injection (YQFM), a traditional Chinese medicine (TCM) prescription re-developed based on Sheng-Mai-San, is widely applied for the treatment of cardiovascular diseases. …”
Publicado 2019
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663por Gao, Xiaolei, Zheng, Xuan, Zhang, Yixin, Dong, Liying, Sun, Liangjie, Zhao, Na, Ding, Chong, Ma, Zeyun, Wang, Yixiang“…The mutant cancer cells were also observed to be significantly resistant to 5-FU. Xenografts also confirmed that HCT116 cells harboring deficient or mutant p53 promoted cancer growth and 5-FU tolerance. …”
Publicado 2022
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667por Battaglin, Francesca, Schirripa, Marta, Buggin, Federica, Pietrantonio, Filippo, Morano, Federica, Boscolo, Giorgia, Tonini, Giuseppe, Lutrino, Eufemia Stefania, Lucchetti, Jessica, Salvatore, Lisa, Passardi, Alessandro, Cremolini, Chiara, Arnoldi, Ermenegildo, Scartozzi, Mario, Pella, Nicoletta, Boni, Luca, Bergamo, Francesca, Zagonel, Vittorina, Loupakis, Fotios, Lonardi, Sara“…DISCUSSION: The PANDA study aims at exploring safety and efficacy of panitumumab in combination with FOLFOX or with 5FU/LV in elderly patients affected by RAS and BRAF wild-type metastatic colorectal cancer, to identify the most promising treatment strategy in this setting. …”
Publicado 2018
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668por Kim, Myung Kwan, Leem, Jungtae, Kim, Young Il, Kim, Eunseok, Park, Yang Chun, Sul, Jae-Uk, Jo, Hee-Geun, Yoon, Sang-hoon, Kim, Jeeyong, Jeon, Ju-Hyun, Jung, In Chul“…BACKGROUND: Gyejigachulbutang (GUI-ZHI-JIA-SHU-FU-TANG, GCB) is an herbal formula widely prescribed in traditional East Asian medicine practice for arthritis and muscle pain. …”
Publicado 2020
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669por Tsakonas, Georgios, Specht, Lena, Kristensen, Claus Andrup, Moreno, Maria Herlestam Calero, Haugen Cange, Hedda, Soderstrom, Karin, Friesland, Signe“…SIMPLE SUMMARY: The purpose of the CET-MET trial was to find a new platinum- based chemotherapy regimen in combination with cetuximab for relapsed or metastatic squamous cell carcinoma of the head and neck (RM- SCCHN), that would achieve an equivalent PFS with standard cetuximab and 5-FU/platinum-based chemotherapy (EXTREME regimen), albeit with less toxicity. …”
Publicado 2020
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670por Balahura, Liliana-Roxana, Dinescu, Sorina, Balaș, Mihaela, Cernencu, Alexandra, Lungu, Adriana, Vlăsceanu, George Mihail, Iovu, Horia, Costache, Marieta“…The structure and biocompatibility analysis of a hydrogel based on cellulose nanofibers (CNFs) combined with alginate/pectin (A.CNF or P.CNF) and enriched with 1% or 5% 5-FU revealed more favorable properties for the cellular component when pectin was dispersed within CNFs. 5-Fluorouracil (5-FU) is an antimetabolite fluoropyrimidine used as antineoplastic drug for the treatment of multiple solid tumors. 5-FU activity leads to caspase-1 activation, secretion and maturation of interleukins (IL)-1, IL-18 and reactive oxygen species (ROS) generation. …”
Publicado 2021
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671por Jiang, Lin, Zhang, Yingjing, Su, Pengfei, Ma, Zhiqiang, Ye, Xin, Kang, Weiming, Liu, Yuqin, Yu, Jianchun“…CONCLUSIONS: The findings from the current study showed HNF1A-AS1 promoted 5-FU resistance by acting as a ceRNA of miR-30b-5p and promoting EIF5A2-induced EMT process in GC. …”
Publicado 2022
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672“…XueFu ZhuYu Decoction (XFZYD) is an effective prescription that is widely used to improve blood circulation by removing blood stasis. …”
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673por Ko, Mi Mi, Kim, Pyung-Wha, Jung, So Young, Kim, Cheol-Hyun, Lee, Byung-Cheol, Jung, JeeyounEnlace del recurso
Publicado 2023
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674“…Colon cancer is the third most common cancer and the third largest cause of cancer-related death. Fluorouracil (5-FU) is the front-line chemotherapeutic agent for colon cancer. …”
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675por Satake, Hironaga, Tsuji, Akihito, Nakamura, Masato, Ogawa, Masaaki, Kotake, Takeshi, Hatachi, Yukimasa, Yasui, Hisateru, Takagane, Akinori, Okita, Yoshihiro, Nakamura, Kumi, Onikubo, Toshihide, Takeuchi, Masahiro, Fujii, Masashi“…METHODS: Patients received combination therapy consisting of panitumumab (6 mg/kg on day 1) + FOLFOXIRI [irinotecan (CPT-11), oxaliplatin (L-OHP) 85 mg/m(2), and folinate (LV) 200 mg/m(2)] on day 1, followed by fluorouracil (5-FU) 3200 mg/m(2) infused as a 46-h continuous infusion starting on day 1) repeated every 2 weeks as first-line treatment of RAS wild-type mCRC patients. …”
Publicado 2018
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676por Sul, Jae-Uk, Kim, Myung Kwan, Leem, Jungtae, Jo, Hee-Geun, Yoon, Sang-hoon, Kim, Jeeyong, Lee, Eun-Jung, Yoo, Jeong-Eun, Park, So Jung, Kim, Young Il, Kim, Eunseok, Jung, In Chul, Jeon, Ju-Hyun, Park, Yang-ChunEnlace del recurso
Publicado 2019
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678por Kalbakis, K, Kouroussis, Ch, Kakolyris, S, Mavroudis, D, Souglakos, J, Agelaki, S, Vamvakas, L, Christodoulakis, M, Stylianou, K, Georgoulias, V“…Cyclophosphamide (600 mg m(−2)) was given i.v. bolus on day 1 and LV (500 mg m(−2) d(−1)) as a 2-h infusion followed by 5-FU (1.5 g m(−2) d(−1)) over a 22 h c.i. for 2 consecutive days. …”
Publicado 2001
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679por Dahan, Laetitia, Bonnetain, Frank, Ychou, Marc, Mitry, Emmanuel, Gasmi, Mohamed, Raoul, Jean-Luc, Cattan, Stéphane, Phelip, Jean-Marc, Hammel, Pascal, Chauffert, Bruno, Michel, Pierre, Legoux, Jean-Louis, Rougier, Philippe, Bedenne, Laurent, Seitz, Jean-François“…Although the 5-fluorouracil (5FU), folinic acid and cisplatin combination (LV5FU2-CDDP) is an option, the optimal order of the regimens must be determined. …”
Publicado 2010
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680“…BACKGROUND: Although 5-Flourouracil(5-FU) is used as the first-choice treatment for advanced hepatocellular carcinoma (HCC), it is associated with acquired and intrinsic resistance. …”
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