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161por Liu, Xia, Zhu, Wei, Guan, Shuhong, Feng, Ruihong, Zhang, Hui, Liu, Qiuhong, Sun, Peng, Lin, Donghai, Zhang, Naixia, Shen, Jun“…Based on the previous work, we developed and patented an anti-anxiety herbal formula Fu Fang Jin Jing Oral Liquid (FJJOL) with Herba Rhodiolae as a chief ingredient. …”
Publicado 2013
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162por Cheng, Mingrong, Gao, Xiaoyan, Wang, Yong, Chen, Houxiang, He, Bing, Li, Yingchun, Han, Jiang, Zhang, Zhiping“…GCGA nanoparticles significantly prolonged the efficacy of 5-FU on tumor cells, and alleviated the resistance of tumor cells to 5-FU. …”
Publicado 2013
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163por Guo, Na, Liu, Mingtao, Yang, Dawei, Huang, Ying, Niu, Xiaohong, Wu, Ruifan, Liu, Ying, Ma, Guizhi, Dou, Deqiang“…BACKGROUND: Shen-Fu decoction is a traditional Chinese medicine prescription with a 3:2 ratio of Radix Ginseng and Fuzi (Radix Aconiti lateralis praeparata). …”
Publicado 2013
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164por Qian, Ying, Liu, Yanning, Yan, Qiuyue, Lv, Juan, Ni, Xiaoyan, Wu, Yunlu, Dong, Xuejun“…However, Mus81 deficiency did not affect the apoptosis of T47D cells with 5-FU. CONCLUSION: Taken together, our data suggest that Mus81 inhibition significantly increased the chemosensitivity of MCF-7 and T47D cells in response to 5-FU. …”
Publicado 2014
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165“…Multiple-unit-type oral floating hollow microspheres of 5-fluorouracil (5-Fu) were developed using modified solvent evaporation technique to prolong gastric residence time, to target stomach cancer, and to increase drug bioavailability. …”
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166por Bonin, SerenaEnlace del recurso
Publicado 2015
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167por Zhou, Fen, Huang, Dengliang, Li, Yong, Hu, Guanghui, Rao, Hai, Lu, Quqin, Luo, Shiwen, Wang, Yao“…Despite the central importance of SuFu in the Hh pathway, little is known about SuFu regulation. …”
Publicado 2016
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168“…OBJECTIVE: This study aims to investigate cellular immunity and clinical efficacy of ShenQi FuZheng Injection (SFI) in the associated chemotherapy of colorectal cancer (CRC). …”
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169por Hu, Hanqing, Wang, Meng, Guan, Xu, Yuan, Ziming, Liu, Zheng, Zou, Chaoxia, Wang, Guiyu, Gao, Xu, Wang, Xishan“…The present study is aimed to investigate the putative mechanism of ABCB4 in 5-fluorouracil (5-Fu) resistance. Then, we found that ABCB4 was significantly down-regulated in the 5-Fu resistant HCT8 cell lines by polymerase chain reaction (PCR) and Western blot. …”
Publicado 2018
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170por Morawska, Katarzyna, Goirand, Françoise, Marceau, Laurine, Devaux, Madeline, Cueff, Adèle, Bertaut, Aurélie, Vincent, Julie, Bengrine-Lefevre, Leila, Ghiringhelli, François, Schmitt, Antonin“…AIMS: 5-FU is used as the main backbone of chemotherapy regimens for patients with colorectal and other gastrointestinal cancers. …”
Publicado 2018
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171“…The current study aimed to explore the potential function of miR-206 in 5-FU resistance. METHODS: To indentify the role of miR-206 in 5-FU resistance, the expression of miR-206 was examined by real-time polymerase chain reaction (RT-PCR) in 5-FU-resistant (FR) CRC (HCT116/FR and RKO/FR) and their parental cell lines. miR-206 mimic was transfected to 5-FU-FR CRC, and the 5-FU sensitivity was detected by MTS and flow cytometry. …”
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172por van den Broek, Evert, den Uil, Sjoerd H., Coupé, Veerle M.H., Delis-van Diemen, Pien M., Bolijn, Anne S., Bril, Herman, Stockmann, Hein B.A.C., van Grieken, Nicole C.T., Meijer, Gerrit A., Fijneman, Remond J.A.“…CONCLUSION: These data indicate that low nuclear expression of MACROD2 is associated with poor prognosis of patients with stage III MSS primary colon cancer who were treated with 5-FU-based adjuvant chemotherapy.…”
Publicado 2018
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173“…EZH2 knockdown enhanced 5-FU sensitivity of AGS/5-FU and SGC-7901/5-FU cells. …”
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174por Xu, Xiao, Hu, Wenxiu, Zhou, Siduo, Tu, Chuanhai, Xia, Xiudong, Zhang, Juanmei, Dong, Mingsheng“…In this study, we developed a novel fermented glutinous rice product with the supplementation of Fu brick tea. Using in vitro antioxidant evaluation and phenolic compounds analysis, fermentation with Fu brick tea increased the total phenolic content and enhanced the antioxidant activity of glutinous rice, including scavenging of 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) radical, 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical, and hydroxyl radical, ferric-reducing antioxidant power, and ferric ion reducing power and iron chelating capability. …”
Publicado 2019
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175“…Overcoming chemorestistance to 5-fluorouracil (5-FU) could offer a new treatment option for highly malignant colon cancer. …”
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176por Zhang, Qian, Liu, Rui-Xian, Chan, Ka-Wo, Hu, Jiancong, Zhang, Jingdan, Wei, Lili, Tan, Huiliu, Yang, Xiangling, Liu, Huanliang“…BACKGROUND: Acquired resistance remains a limitation of the clinical use of 5-fluorouracil (5-FU). Because exosomes, are important vesicles participating in intercellular communication, their contribution to the development of acquired 5-FU resistance needs to be elucidated. …”
Publicado 2019
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178por Rao, Shuyun, Peri, Suraj, Hoffmann, Jens, Cai, Kathy Q., Harris, Bryan, Rhodes, Michele, Connolly, Denise C., Testa, Joseph R., Wiest, David L.“…In summary, our data suggest that RPL22L1 might be a prognostic marker in CRC and predict 5-FU responsiveness.…”
Publicado 2019
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179por Qu, Ke Shen, Li, Yang, Liang, Yue, Hu, Xiao Jie, Wang, Xuan Yu, Chen, Xin, Que, Hua Fa“…Currently, the existing treatments are not satisfactory enough. In China, KangFuXin liquid (KFXL) has been clinically used to treat DFU and has shown good clinical efficacy. …”
Publicado 2019
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180por Yoshida, Yoichiro, Hashimoto, Yasuhiro, Miyazaki, Makoto, Aisu, Naoya, Yamada, Teppei, Kajitani, Ryuji, Munechika, Taro, Matsumoto, Yoshiko, Nagano, Hideki, Shimaoka, Hideki, Komono, Akira, Sakamoto, Ryohei, Yoshimatsu, Gumpei, Yoshimura, Fumihiro, Kiyomi, Fumiaki, Hasegawa, Suguru“…Capecitabine is selectively converted from 5′-DFUR to 5-fluorouracil (5-FU) in tumours by thymidine phosphorylase (TP). …”
Publicado 2020
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