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  1. 3421
    “…We reported 11 classes of structured ncRNA candidates with significant covariations in humans. Functional analysis showed that these ncRNAs may have variable functions. …”
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    Online Artículo Texto
    Identification of 11 candidate structured noncoding RNA motifs in humans by comparative genomics
  2. 3422
    “…The functional analysis showed that most of the attributes of the microbiome was related to metabolism, followed by cellular processes and environmental information processing functions. …”
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    Online Artículo Texto
    Comparative Metagenomic Analysis of Two Alkaline Hot Springs of Madhya Pradesh, India and Deciphering the Extremophiles for Industrial Enzymes
  3. 3423
    “…Here, an integrated taxonomic and functional analysis of the microbiome of the eastern oyster, Crassostrea virginica, was performed using 16S rRNA gene-based amplicon profiling, shotgun metagenomics, and genome-scale metabolic reconstruction. …”
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    Microbiome Analysis Reveals Diversity and Function of Mollicutes Associated with the Eastern Oyster, Crassostrea virginica
  4. 3424
    “…We demonstrated a general overrepresentation of Clostridiales and underrepresentation of Bacteroidetes in patients with dystonia in comparison with healthy controls. The functional analysis found that genes related to the biosynthesis of tryptophan, which is the precursor of the neurotransmitter serotonin, were more active in isolated dystonia patients. …”
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    Gut Microbiome and Serum Metabolome Alterations Associated with Isolated Dystonia
  5. 3425
    “…The regulation of this gene was intensively analyzed under normal bacterial infection and heat/cold-shock inductions. A functional analysis of this gene under heat and infectious stress conditions was performed by gene knockdown. …”
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    Characterization, Stress Response and Functional Analyses of Giant River Prawn (Macrobrachium rosenbergii) Glucose-Regulated Protein 78 (Mr-grp78) under Temperature Stress and during Aeromonas hydrophila Infection
  6. 3426
    “…SIGNIFICANCE STATEMENT: Here we report, supported by careful phenotyping, genotyping and functional analysis, a prismatic case series of patients with congenital adrenal hyperplasia due to 17α-hydroxylase (CYP17A1) deficiency (17OHD). …”
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    Online Artículo Texto
    The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency: a case series
  7. 3427
    “…The detailed functions were investigated using functional analysis. The single-sample gene set enrichment analysis (ssGSEA) score was used to evaluate the tumor microenvironment. …”
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    Online Artículo Texto
    Development and Validation of a Prognostic Signature Associated With Tumor Microenvironment Based on Autophagy-Related lncRNA Analysis in Hepatocellular Carcinoma
  8. 3428
    “…Moreover, our mutagenesis approach serves as a guide for the functional analysis of other complex multicistronic viral loci. …”
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    Online Artículo Texto
    A Panel of Kaposi’s Sarcoma-Associated Herpesvirus Mutants in the Polycistronic Kaposin Locus for Precise Analysis of Individual Protein Products
  9. 3429
    “…Following synbiotic supplementation, microbiome analysis revealed increased microbial diversity, and functional analysis of the microbiota showed an increased abundance of carbohydrate and lipid metabolism. …”
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    Online Artículo Texto
    Effects of Synbiotic Preparation Containing Lactobacillus gasseri BNR17 on Body Fat in Obese Dogs: A Pilot Study
  10. 3430
    “…Several tools were used to predict the miRNAs targeted by the circRNAs and the miRNAs targeted mRNAs, which then overlapped with the cocaine-associated differentially expressed mRNAs to determine the functional roles of circRNAs. Functional analysis for the obtained mRNAs was performed via Gene Ontology (GO) in Metascape database. …”
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    Online Artículo Texto
    Identification of Functional CircRNA–miRNA–mRNA Regulatory Network in Dorsolateral Prefrontal Cortex Neurons of Patients With Cocaine Use Disorder
  11. 3431
    por Schwarz, Niklas, Seiffert, Simone, Pendziwiat, Manuela, Rademacher, Annika Verena, Brünger, Tobias, Hedrich, Ulrike B.S., Augustijn, Paul B., Baier, Hartmut, Bayat, Allan, Bisulli, Francesca, Buono, Russell J., Bruria, Ben Zeev, Doyle, Michael G., Guerrini, Renzo, Heimer, Gali, Iacomino, Michele, Kearney, Hugh, Klein, Karl Martin, Kousiappa, Ioanna, Kunz, Wolfram S., Lerche, Holger, Licchetta, Laura, Lohmann, Ebba, Minardi, Raffaella, McDonald, Marie, Montgomery, Sarah, Mulahasanovic, Lejla, Oegema, Renske, Ortal, Barel, Papacostas, Savvas S., Ragona, Francesca, Granata, Tiziana, Reif, Phillip S., Rosenow, Felix, Rothschild, Annick, Scudieri, Paolo, Striano, Pasquale, Tinuper, Paolo, Tanteles, George A., Vetro, Annalisa, Zahnert, Felix, Goldberg, Ethan M., Zara, Federico, Lal, Dennis, May, Patrick, Muhle, Hiltrud, Helbig, Ingo, Weber, Yvonne
    Publicado 2022
    “…METHODS: Individuals with KCNC2 variants detected by exome sequencing were selected for clinical, further genetic, and functional analysis. Cases were referred through clinical and research collaborations. …”
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    Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With KCNC2 Pathogenic Variants
  12. 3432
    “…Subsequently, gene clustering and a functional analysis were performed to explore the roles of the DEGs. …”
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    Online Artículo Texto
    Identification of candidate biomarkers associated with gastric cancer prognosis based on an integrated bioinformatics analysis
  13. 3433
    “…Methods: We developed an in vitro mammalian cell expression and functional analysis system based on guidelines established by the Clinical Genome Resource (ClinGen) Sequence Variant Interpretation Working Group for PS3/BS3. …”
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    Development of a clinically validated in vitro functional assay to assess pathogenicity of novel GAA variants in patients with Pompe disease identified via newborn screening
  14. 3434
    por Guo, Ziwei, Liang, Jun
    Publicado 2022
    “…ER stress was considered as an important component by functional analysis. A 10-gene risk signature compared the clinicopathology characteristics, immunosuppressive events and a nomogram in HCC patients. …”
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    Online Artículo Texto
    Characterization of a lipid droplet and endoplasmic reticulum stress related gene risk signature to evaluate the clinical and biological value in hepatocellular carcinoma
  15. 3435
    “…Phosphoproteomics was employed to dissect the molecular regulation mechanisms of F1 cross chicken cecum infected with S. Enteritidis. Functional analysis and functional classification were performed for those differentially phosphorylated proteins (DPPs). …”
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    Phosphoproteomics Profile of Chicken Cecum in the Response to Salmonella enterica Serovar Enteritidis Inoculation
  16. 3436
    “…The results showed 5 SNPs significantly associated with reproductive efficiency, located in two genomic regions (BTA4 and BTA28). The functional analysis revealed the presence of 5 candidate genes located within these regions, which were previously involved in different aspects related to fertility in cattle and mice models. …”
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    Estimation of the Genetic Components of (Co)variance and Preliminary Genome-Wide Association Study for Reproductive Efficiency in Retinta Beef Cattle
  17. 3437
    “…Machine cryogenic equipment is installed in a 26.7-km circumference ring deep underground tunnel and are maintained at their nominal operating conditions via a distribution system consisting of transfer lines, cold interconnection boxes at each cryogenic island and a cryogenic distribution line. The functional analysis of the whole system during all operating conditions was established and validated during the first sector commissioning in order to maximize the system availability. …”
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    Validation and Performance of the LHC Cryogenic System through Commissioning of the First Sector
  18. 3438
    “…The exposition is self-contained; in the first part the reader finds the mathematical background in chapters about functional analysis, operators on Hilbert spaces and their spectral theory, as well as operator sets and algebras. …”
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    Hilbert Space Operators in Quantum Physics
  19. 3439
    “…The selected topics are: - Real analysis, Complex analysis, Functional analysis, Lebesgue integration theory, Fourier analysis, Laplace analysis, Wavelet analysis, Differential equations, and Tensor analysis. …”
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    Higher Mathematics for Physics and Engineering: Mathematical Methods for Contemporary Physics
  20. 3440
    por Spataru, Aurel
    Publicado 2013
    “…The initial section will also be useful for those interested in topology, measure theory, real analysis and functional analysis. The second part of the book presents the concepts, methodology and fundamental results of probability theory. …”
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    Analysis and probability
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