“…Here, we describe HeLa cell lines, in which we have identified—by functional analysis—genomic loci, from which the expression of transgenes can be tightly controlled via tetracycline-regulated expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…GeneCodis is a web server application for functional analysis of gene lists that integrates different sources of information and finds modular patterns of interrelated annotations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: The Globaltest identified significantly associated gene sets in one of the three contrasts made in the microarray experiment whereas the functional analysis of the differentially expressed genes using GOEAST revealed enriched GO terms in all three contrasts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The N-terminal RfaH domain (RfaH(N)) recognizes the ops element, binds to the RNAP and reduces pausing and termination in vitro. Functional analysis of single substitutions in this domain reported here suggests that three separate RfaH(N) regions mediate these functions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Functional analysis of multiple genes is key to understanding gene regulatory networks controlling embryonic development. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…African trypanosomes possess only two candidate myosins and thus represent a useful system for functional analysis of these motors. One of these candidates is an unusual class I myosin (TbMyo1) that is expressed at similar levels but organized differently during the life cycle of Trypanosoma brucei. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study reports the isolation and functional analysis of RAV1, which encodes a RAV family transcription factor. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Systematic study of cell signaling networks increasingly involves high throughput proteomics, transcriptional profiling, and automated literature mining with the aim of assembling large scale interaction networks. In contrast, functional analysis of cell signaling usually focuses on a much smaller sets of proteins and eschews computation but focuses directly on cellular responses to environment and perturbation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, differences in expression profiles indicate that the abomasum, rumen, and intestine are more closely related to each other, while the reticulum and omasum are more closely related to the rumen. Functional analysis using Gene Ontology (GO) categories also supports the proposed evolutionary relationships by identifying shared functions, such as muscle activity and development, lipid transport, and urea metabolism, between all sections of the digestive tract investigated.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Because most of these proteins have no known function, the task of functional analysis of these proteins and the discovery of novel pharmacologically active compounds becomes possible.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results broaden the mutational spectrum in FATP4 associated with IPS for molecular diagnosis of and further functional analysis of FATP4.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The genes identified in this study represent valuable candidates for further functional analysis in UM and should be informative in studying the biology of this tumor.…”
Enlace del recurso
Enlace del recurso

“…To investigate the pathogenicity of this bacterium, we cloned exfoliative toxin C (ExhC), a major toxin of the S. sciuri isolate and performed functional analysis of the recombinant ExhC-his (rExhC) protein using in vitro cell cultures and newborn mice as models. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Gd-EOB-DTPA is also emerging as a promising tool for functional analysis, enabling the calculation of post-surgical liver function in the remaining segments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Detailed X-ray structural and functional analysis shed light on why serine-for-alanine mistranslation is a universal problem, and on the selective pressures that engendered the appearance of AlaXps at the base of the Tree of Life.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we show that a Bayesian statistical framework by VoyaGene(®) identified a secreted protein acidic and rich in cysteine (SPARC) gene, a tumor-invasiveness related gene, as a possible modulator of bortezomib-induced cell death in ATL cells. Functional analysis using RNAi experiments revealed that inhibition of the expression SPARC by siRNA enhanced the apoptotic effect of bortezomib on ATL cells in accordance with an increase of cleaved caspase 3. …”
Enlace del recurso
Enlace del recurso

“…With the permutation test method, we identified a set of genes with significant changes in the inequality and duality measure of edge weight. Functional analysis shows that these genes are highly enriched for the immune system, which plays an essential role in the Sym-Pat duality (SPD) of microbial infections. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Dynamic neuronal networks are a key paradigm of increasing importance in brain research, concerned with the functional analysis of biological neuronal networks and, at the same time, with the synthesis of artificial brain-like systems. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review addresses the current state of research and experimental data regarding embryonic stem cells (ESCs), myoblast transplantation, histological and functional analysis of transplantation of co-cultured myoblasts and mesenchymal stem cells, as well as comparison between mononuclear and mesenchymal stem cells in a model of myocardium infarction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Our results demonstrate that the new pEG101-SacB/R destination vector can be used for Gateway(® )cloning in Agrobacterium tumefaciens. pEG101-SacB/R will be a valuable tool for high-throughput functional analysis of genes in planta.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso