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Análisis funcional
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Climatic variables influence annual P. montezumae growth
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4041por Gregoracci, Gustavo B., Nascimento, Juliana R., Cabral, Anderson S., Paranhos, Rodolfo, Valentin, Jean L., Thompson, Cristiane C., Thompson, Fabiano L.“…According to the subsystems (SEED) functional analysis, GB has a distinctive metabolic signature, comprising a higher number of sequences in the metabolism of phosphorus and aromatic compounds and a lower number of sequences in the photosynthesis subsystem. …”
Publicado 2012
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4042“…Here we report the identification and functional analysis of the novel cis-encoded sRNA h2cR, from the human opportunistic pathogen Burkholderia cenocepacia J2315. …”
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4043por Hsu, Ku-Lung, Tsuboi, Katsunori, Adibekian, Alexander, Pugh, Holly, Masuda, Kim, Cravatt, Benjamin F.“…Here, we report a series of in vivo-active 1,2,3-triazole urea inhibitors, along with paired negative-control and activity-based probes, for the functional analysis of DAGLβ in living systems. Optimized inhibitors showed excellent selectivity for DAGLβ over other serine hydrolases, including DAGLα (~60-fold selectivity), and the limited off-targets, such as ABHD6, were also inhibited by the negative-control probe. …”
Publicado 2012
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4044por Mullokandov, Gavriel, Baccarini, Alessia, Ruzo, Albert, Jayaprakash, Anitha D., Tung, Navpreet, Israelow, Benjamin, Evans, Matthew J., Sachidanandam, Ravi, Brown, Brian D.“…We introduce two large-scale resources for functional analysis of microRNA—a decoy/sponge library for inhibiting microRNA function and a sensor library for monitoring microRNA activity. …”
Publicado 2012
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4045por Zhang, Xiujun, Hao, Lili, Meng, Lijun, Liu, Meiling, Zhao, Lina, Hu, Fen, Ding, Cunbao, Wang, Yang, He, Baoling, Pan, Yuxin, Fang, Wei, Chen, Jing, Hu, Songnian, Jia, Mengchun“…Gene expression patterns vary significantly between mouse type B spermatogonia and primary spermatocytes. The functional analysis revealed that genes related to junction assembly, regulation of the actin cytoskeleton and pluripotency were most significantly differently expressed. …”
Publicado 2013
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4046por Wei, Tong, Ou, Bin, Li, Jinbin, Zhao, Yang, Guo, Dongshu, Zhu, Youyong, Chen, Zhangliang, Gu, Hongya, Li, Chengyun, Qin, Genji, Qu, Li-Jia“…We found that the transcriptional profiles of rice compatible and incompatible interactions with M. oryzae were mostly similar, with genes regulated more prominently in the incompatible interactions. The functional analysis showed that the genes involved in signaling and secondary metabolism were extensively up-regulated. …”
Publicado 2013
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4047“…BACKGROUND: In a functional analysis of gene expression data, biclustering method can give crucial information by showing correlated gene expression patterns under a subset of conditions. …”
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4048por Kandoth, Pramod K, Heinz, Robert, Yeckel, Greg, Gross, Nathan W, Juvale, Parijat S, Hill, John, Whitham, Steven A, Baum, Thomas J, Mitchum, Melissa G“…BACKGROUND: Bean pod mottle virus (BPMV) based virus-induced gene silencing (VIGS) vectors have been developed and used in soybean for the functional analysis of genes involved in disease resistance to foliar pathogens. …”
Publicado 2013
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4049“…Subsequent gene expression analysis identified 998 differentially expressed transcripts and functional analysis revealed that metal- and ion-homeostasis pathways are likely to be the most important mechanisms contributing to the metal tolerance exhibited by this population.…”
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4050“…This annotation and functional analysis supports multiple roles for U. maydis NATs in controlling gene expression and influencing pathogenesis.…”
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4051por Zhou, Jiao, Zhang, Haolin, Li, Juan, Sheng, Xia, Zong, Shixiang, Luo, Youqing, Nagaoka, Kentaro, Weng, Qiang, Watanabe, Gen, Taya, Kazuyoshi“…These results suggest that the sequence character and expression profile of HhSpo were well conserved and provided the basic information for its functional analysis.…”
Publicado 2013
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4052por Horn, Henning F., Kim, Dae In, Wright, Graham D., Wong, Esther Sook Miin, Stewart, Colin L., Burke, Brian, Roux, Kyle J.“…Here we provide a functional analysis of KASH5, a mammalian dynein-binding protein of the outer nuclear membrane that forms a meiotic complex with Sun1. …”
Publicado 2013
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4053por Cantacessi, Cinzia, Seddon, Jennifer M., Miller, Terrence L., Leow, Chiuan Yee, Thomas, Laëtitia, Mason, Lyndel, Willis, Charlene, Walker, Giselle, Loukas, Alex, Gasser, Robin B., Jones, Malcolm K., Hofmann, Andreas“…This study illuminates annexin diversity from a novel perspective using contemporary phylogenetic hypotheses of eukaryote evolution, and will aid the consolidation of annexin protein identities in public databases and provide a foundation for future functional analysis and characterisation of these proteins in parasites of socioeconomic importance.…”
Publicado 2013
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4054por Yuan, Xiaowei, Zhang, Shizhong, Sun, Meihong, Liu, Shiyang, Qi, Baoxiu, Li, Xinzheng“…Our data provide a useful reference for the identification and functional analysis of the members of this protein family.…”
Publicado 2013
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4055por Abiatari, Ivane, Esposito, Irene, Oliveira, Tiago De, Felix, Klaus, Xin, Hong, Penzel, Roland, Giese, Thomas, Friess, Helmut, Kleeff, Jörg“…Cancer cells of different malignant lesions of human and transgenic mice pancreata were evaluated by immunohistochemistry. For functional analysis, cell growth, adhesion and invasion assays were carried out after transient and stable knock-down of moesin expression in pancreatic cancer cells. …”
Publicado 2010
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4056por Chen, Eric CH, Buen Abad Najar, Carlos Fernando, Zheng, Chunfang, Brandts, Alex, Lyons, Eric, Tang, Haibao, Carretero-Paulet, Lorenzo, Albert, Victor A, Sankoff, David“…CONCLUSIONS: The gene loss analysis represents an assessment of post-polyploidization evolution, at the level of individual gene families within and across sister genomes. Functional analysis confirms universal trends previously reported for more recent plant polyploidy events: genes involved with regulation and responses were retained in multiple copies, while genes involved with metabolic and catalytic processes tended to lose copies, across all three groups of plants.…”
Publicado 2013
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4057por Lambrot, R., Xu, C., Saint-Phar, S., Chountalos, G., Cohen, T., Paquet, M., Suderman, M., Hallett, M., Kimmins, S.“…Genome-wide DNA methylation analysis and the subsequent functional analysis identify differential methylation in sperm of genes implicated in development, chronic diseases such as cancer, diabetes, autism and schizophrenia. …”
Publicado 2013
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4058por Pandian, Ganesh N., Taniguchi, Junichi, Junetha, Syed, Sato, Shinsuke, Han, Le, Saha, Abhijit, AnandhaKumar, Chandran, Bando, Toshikazu, Nagase, Hiroki, Vaijayanthi, Thangavel, Taylor, Rhys D., Sugiyama, Hiroshi“…Through microarray studies and functional analysis, here we demonstrate for the first time the remarkable ability of thirty-two different SAHA-PIPs to trigger the transcriptional activation of exclusive clusters of genes and noncoding RNAs. …”
Publicado 2014
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4059por Amir, Asad, Rana, Khyati, Arya, Arvind, Kapoor, Neelesh, Kumar, Hirdesh, Siddiqui, Mohd Asif“…These enzymes were also found to be essential for survival of the Mycobacterium tuberculosis according to the DEG database. Further, the functional analysis using Uniprot showed involvement of all the unique enzymes in the different cellular components.…”
Publicado 2014
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4060por Cukusic Kalajzic, Andrea, Skrobot Vidacek, Nikolina, Huzak, Miljenko, Ivankovic, Milena, Rubelj, Ivica“…Structural and functional analysis of telomeres is very important for understanding basic biological functions such as genome stability, cell growth control, senescence and aging. …”
Publicado 2014
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