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  1. 4161
    “…In this study, we found that the transcripts of 10 banana ATG8s responded to drought stress in different ways, and MaATG8f with the highest transcript in response to drought stress among them was chosen for functional analysis. Overexpression of MaATG8f improved drought stress resistance in Arabidopsis, with lower malonaldehyde level and higher level of assimilation rate. …”
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    Overexpression of Banana ATG8f Modulates Drought Stress Resistance in Arabidopsis
  2. 4162
    “…Of interest, serine protease activity was 10-fold higher in IBD fecal samples compared to healthy controls. Moreover, functional analysis of these fecal proteolytic activities revealed that the most increased activities are trypsin-like, elastase-like and cathepsin G-like. …”
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    Fecal Serine Protease Profiling in Inflammatory Bowel Diseases
  3. 4163
    “…Methods: In this study, we examined NCAPH expression in OSCC and performed a functional analysis of human OSCC cells. Results: NCAPH expression was higher in OSCC than in normal oral mucosa. …”
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    Non-SMC Condensin I Complex Subunit H (NCAPH) Is Associated with Lymphangiogenesis and Drug Resistance in Oral Squamous Cell Carcinoma
  4. 4164
    “…In the current report, we show the in vivo and in vitro overexpression of S6K1 in HCC. In the functional analysis, we demonstrate that S6K1 is required for the proliferation and colony formation abilities in HCC. …”
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    Transcriptomic analysis reveals the oncogenic role of S6K1 in hepatocellular carcinoma
  5. 4165
    “…Provisioned macaques also showed a higher abundance of Firmicutes and a lower abundance of Bacteroidetes than wild macaques. Functional analysis revealed that wild macaques had enriched microbial pathways involved in glycan biosynthesis and metabolism, transport and catabolism, and the digestive and endocrine systems, while provisioned macaques were richer in pathways associated with signaling molecules and interaction, neurodegenerative diseases. …”
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    Gut microbiota of provisioned and wild rhesus macaques (Macaca mulatta) living in a limestone forest in southwest Guangxi, China
  6. 4166
    “…Furthermore, a functional analysis in C. elegans was used. We found that feeding C. elegans the micronutrient blend increased longevity as well as vitality. …”
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    A Novel Micronutrient Blend Mimics Calorie Restriction Transcriptomics in Multiple Tissues of Mice and Increases Lifespan and Mobility in C. elegans
  7. 4167
    “…More recent efforts have moved beyond genetic analysis to functional analysis of the molecules involved, including identification of immunodominant antigens and peptides as well as the role of post-translational glycosylation. …”
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    Microarrays in infection and immunity
  8. 4168
    “…We performed the bioinformatic functional analysis and gene ontology classification. We also identified 12 differentially regulated miRNAs, from which three can influence the two targets (assigned as DEGs) in one of the studied transgenic lines (line 224). …”
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    Effect of Transgenesis on mRNA and miRNA Profiles in Cucumber Fruits Expressing Thaumatin II
  9. 4169
    “…Highly upregulated expression was observed for ribosomal proteins such as RplB, Rpsl, RpsR, DNA damage response proteins (DdrA, DdrB), DNA repair proteins (RecN, RecA), and transcriptional regulators (members of TetR, AsnC, and GntR families, DdrI). The functional analysis of proteins in response to oxidative stress is discussed in detail. …”
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    Comparative Proteomics Analysis Reveals New Features of the Oxidative Stress Response in the Polyextremophilic Bacterium Deinococcus radiodurans
  10. 4170
    por Martínez-Salas, Encarnación
    Publicado 2008
    “…The biological relevance of RNA structure-mediated mechanisms involved in internal ribosome recruitment is now emerging from the structural and functional analysis of viral IRES elements. However, because IRES elements found in genetically distant mRNAs seem to be organized in different RNA structures, the definition of the structural requirements for IRES activity is challenging and demands multidisciplinary approaches. …”
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    The impact of RNA structure on picornavirus IRES activity
  11. 4171
    “…KEGG and gene ontology functional analysis revealed that genes up-regulated in the presence of GOS were involved in digestion and absorption processes, fatty acids and steroids metabolism, potential antimicrobial proteins, energy-dependent and -independent transmembrane trafficking of solutes and amino acids. …”
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    In Vitro Evaluation of the Effects of Commercial Prebiotic GOS and FOS Products on Human Colonic Caco–2 Cells
  12. 4172
    “…Here, we studied the role of apelin/APLNR signaling in GBM angiogenesis and growth. By functional analysis of apelin in orthotopic GBM mouse models, we found that apelin/APLNR signaling is required for in vivo tumor angiogenesis. …”
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    Apelin Controls Angiogenesis-Dependent Glioblastoma Growth
  13. 4173
    “…Dietary RNA interference (RNAi)-based functional analysis showed substantially reduced fecundity in parthenogenetically reproduced females, suggesting a potential role of BtabCSP11 in B. tabaci reproduction. …”
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    A Chemosensory Protein BtabCSP11 Mediates Reproduction in Bemisia tabaci
  14. 4174
    “…Gene ontology annotation was performed to investigate the functional analysis of the genes. To uncover the metabolic pathway of these differentially expressed genes, they were mapped into the KEGG BRITE pathway database. …”
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    Studying the Gene Expression of Penicillium rubens Under the Effect of Eight Essential Oils
  15. 4175
    “…Among the HBV genome integrants, we performed functional analysis and demonstrated the automatic expression of some HBV proteins encoded by HBV integrants from chromosomes 3 and 11 in Huh7 cells transfected with these DNA sequences. …”
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    Analysis of HBV Genomes Integrated into the Genomes of Human Hepatoma PLC/PRF/5 Cells by HBV Sequence Capture-Based Next-Generation Sequencing
  16. 4176
    “…Methods to analyze this phenomenon are particularly relevant to evaluate crop agronomic performance, to genetically dissect out the wilting process, and for functional analysis of genetically modified plants. In this study, a low-cost, semi-automated method to quantify leaf folding of wilting plants is described that can replace visual analysis. …”
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    A Low-Cost Method for Phenotyping Wilting and Recovery of Wheat Leaves under Heat Stress Using Semi-Automated Image Analysis
  17. 4177
    “…Although most of the studies only stayed in the stage of initial discovery, several proteins were further verified to be efficient for disease diagnosis. Functional analysis of all the combined significant proteins also showed that a small number of proteins are known to be involved in the regulation of insulin or indirect signaling pathways. …”
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    A Critical Review of Proteomic Studies in Gestational Diabetes Mellitus
  18. 4178
    por Wójcik, Anna Maria
    Publicado 2020
    “…Here, we attempted to summarise the toolbox for functional analysis of miRNAs during plant embryogenesis. …”
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    Research Tools for the Functional Genomics of Plant miRNAs During Zygotic and Somatic Embryogenesis
  19. 4179
    “…Interactions between the transmembrane portions of the subunits may also contribute, but the nature of transmembrane packing is unclear. Using functional analysis of a mutagenesis scan, biochemistry, and modeling, we find that the subunits form a dimer interface along the entire length of S1, and also have intersubunit contacts between S1 and S4. …”
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    Dimer interaction in the Hv1 proton channel
  20. 4180
    “…Only 12 of these genes maintained high expression activity during late larval development. Functional analysis of two larval proteins, MmCPR3 and MmCPR14, suggested their important role in the proper organization of the cuticle layers of larvae. …”
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    Identification and temporal expression profiles of cuticular proteins in the endoparasitoid wasp, Microplitis mediator
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