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  1. 9721
    “…A total of 2838 genes were found to be differentially expressed, among which 1495 genes were significantly downregulated and 1343 genes were significantly upregulated in the CMS line. Functional analysis showed that most of the differentially expressed genes (DEGs) were involved in protein processing in the endoplasmic reticulum, plant hormone signal transduction, and biosynthesis. …”
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    Differentially Expressed Genes between Carrot Petaloid Cytoplasmic Male Sterile and Maintainer during Floral Development
  2. 9722
    “…We used 2D-gel electrophoresis-based proteomics and tandem mass spectrometry followed by a functional analysis using Ingenuity Pathway analysis (IPA) to evaluate functional pathways associated with the luteinization process. …”
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    Proteomic Analysis of Porcine Pre-ovulatory Follicle Differentiation Into Corpus Luteum
  3. 9723
    “…These data will apply to functional analysis on the glossiness and the MAS breeding program to improve the eating quality of japonica as a donor line. …”
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    Improving the Glossiness of Cooked Rice, an Important Component of Visual Rice Grain Quality
  4. 9724
    “…Two stable QTL regions were identified on chromosomes 2 and 16, and gene content within these regions provided valuable information for further functional analysis of yield component traits. CONCLUSIONS: This study represents a new HDGM based on the cultivated peanut genome using SLAF-seq and SSRs. …”
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    QTL identification for seed weight and size based on a high-density SLAF-seq genetic map in peanut (Arachis hypogaea L.)
  5. 9725
    “…C. ramosum was positively correlated with 5-HT (rcm: 0.85, P < 0.001). A functional analysis of the intestinal flora showed that NPC_F was associated with Neurodegenerative Diseases (P = 0.023) and that NPC_S was associated with Neurodegenerative Diseases (P = 0.045) as well. …”
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    Intestinal Flora Disruption and Novel Biomarkers Associated With Nasopharyngeal Carcinoma
  6. 9726
    “…Gene oncology (GO) and gene set enrichment analysis (GSEA) were performed for the functional analysis of the seven-gene-based risk signature. …”
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    Gene Expression Profiling Stratifies IDH-Wildtype Glioblastoma With Distinct Prognoses
  7. 9727
    por Rahimmanesh, Ilnaz, Fatehi, Razieh
    Publicado 2020
    “…Furthermore, the functional analysis resulted in which most of them are expected to be associated with ADPKD pathogenesis, such as signal pathways that involved in cell growth, inflammation, and cell polarity. …”
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    Systems biology approaches toward autosomal dominant polycystic kidney disease (ADPKD)
  8. 9728
    “…Downregulation of caveolin-1 significantly alleviated AFB1-induced apoptosis and decreased cell viability, whereas overexpression of caveolin-1 reversed these effects. Further functional analysis showed that caveolin-1 participates in AFB1-induced oxidative stress through its interaction with Nrf2, leading to the downregulation of cellular antioxidant enzymes and the promotion of oxidative stress-induced apoptosis. …”
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    Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy
  9. 9729
    “…To develop methodology for functional analysis of miRNAs in tapeworms, we performed miRNA knockdown experiments in primary cell cultures of Echinococcus multilocularis, which mimic the development of metacestode vesicles from parasite stem cells in vitro. …”
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    Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro
  10. 9730
    “…We found that several hub genes (e.g., tumor necrosis factor, interleukin 1 beta, interleukin 6, C-X-C motif chemokine ligand 1, C-X-C motif chemokine ligand 2) were marked as significant biomarkers. Functional analysis suggested that these genes were enriched in the Toll-like receptor signaling pathway. …”
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    Identification of candidate biomarkers correlated with pathogenesis of postoperative peritoneal adhesion by using microarray analysis
  11. 9731
    “…The expression levels of the crucial genes from the functional analysis were also confirmed by quantitative PCR (qPCR). …”
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    Microarray Expression Profiling and Raman Spectroscopy Reveal Anti-Fatty Liver Action of Berberine in a Diet-Induced Larval Zebrafish Model
  12. 9732
    “…We then determined IC(50) and combination index values using Calcusyn. Functional analysis of single and combination treatments was performed using reverse phase protein array and cell cycle analysis. …”
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    Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer
  13. 9733
    “…METHODS: Between January 2001 and June 2018, patients suspected of having PIDs were subjected to FCM tests, including lymphocyte subset analysis, detection of surface- or intracellular-target proteins, and functional analysis of immune cells, at Samsung Medical Center, Seoul, Korea. …”
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    Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases: A Single Center Experience
  14. 9734
    “…Among them, 5723 genes were up-regulated, and 8515 genes were down-regulated. Functional analysis revealed the coordination of tuber plant involved in processes of cell events, metabolism, biosynthesis, and signal transduction pathways at transcriptional level, suggesting that these differentially expressed genes are somehow involved in response to tuber expansion, including CDPK, CaM, CDL, SAUR, DELLA, SuSy, and expansin. …”
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    Integrated mRNA and miRNA transcriptome analysis reveals a regulatory network for tuber expansion in Chinese yam (Dioscorea opposita)
  15. 9735
    “…Using reverse transcription-polymerase chain reaction (RT-PCR), miR-210-5p was found to be upregulated in clinical OS specimens and cell lines. Further functional analysis demonstrated that miR-210-5p promoted epithelial–mesenchymal transition (EMT) and induced oncogenic autophagy. …”
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    miR-210-5p promotes epithelial–mesenchymal transition by inhibiting PIK3R5 thereby activating oncogenic autophagy in osteosarcoma cells
  16. 9736
    “…The molecules were characterized as peptides of the class of ocellatins and were named as Ocellatin-K1(1–16) and Ocellatin-K1(1–21). Functional analysis revealed that Ocellatin-K1(1–16) and Ocellatin-K1(1–21) showed weak antibacterial activity. …”
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    Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons
  17. 9737
    “…This is the first to report on the bHLH gene family analysis in B. oleracea and B. napus, which can offer useful information on the functional analysis of the bHLH gene in plants.…”
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    Comparative analysis of basic helix–loop–helix gene family among Brassica oleracea, Brassica rapa, and Brassica napus
  18. 9738
    “…To further investigate the termite microbiomes as sources of biotechnologically relevant glycosyl hydrolases, a putative GH10 endo-β-1,4-xylanase, Xyl10E, was cloned and expressed in Escherichia coli. Functional analysis of the recombinant metagenome-derived enzyme showed high specificity towards beechwood xylan (288.1 IU/mg), with the optimum activity at 50 °C and a pH-activity range from 5 to 10. …”
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    Neotropical termite microbiomes as sources of novel plant cell wall degrading enzymes
  19. 9739
    “…In the present study, we performed an elaborate phenotypical and functional analysis of the chBMDC culture and addressed its heterogeneity. …”
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    In vitro Chicken Bone Marrow-Derived Dendritic Cells Comprise Subsets at Different States of Maturation
  20. 9740
    “…Nevertheless, systemic identification and functional analysis of GCs in crop plant species have not yet been conducted. …”
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    Characterization of tomato protein kinases embedding guanylate cyclase catalytic center motif
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