Mostrando 9,781 - 9,800 Resultados de 12,750 Para Buscar '"functional analysis"', tiempo de consulta: 4.11s Limitar resultados
  1. 9781
  2. 9782
  3. 9783
    “…The target miRNAs of DE-circRNAs and the bidirectional interaction between target miRNAs and DEGs were predicted. Functional analysis was performed, and the protein-protein interaction (PPI) network and the circRNA-miRNA-mRNA network were established. …”
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  4. 9784
  5. 9785
    por Rui, Li, Haonan, Li, Wanyi, Chen
    Publicado 2020
    “…It suggests the interaction between SARS-CoV2 S spike protein complex might have different binding conformations, which request full-length of SARS-CoV2 S protein complex in the structure-functional analysis. In this study, we built a full-length SARS-CoV2 S protein with human ACE2 complex by computational methods. …”
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  6. 9786
    “…Here, we developed a WBPH-resistant rice cultivar by overexpressing the OsF3H gene. A genetic functional analysis of the OsF3H gene confirmed its role in facilitating flavonoid contents and have indicated that the expression of the OsF3H gene is involved in regulation of the downstream genes (OsDFR and OsFLS) of the flavonoid pathway and genes (OsSLR1 and OsWRKY13) involved in other physiological pathways. …”
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  7. 9787
    “…Prognostic factors were identified using univariate Cox regression analysis. Functional analysis was performed using GO, KEGG pathways, and PPI network. …”
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  8. 9788
    “…In two lymphoma patients who exhibited resistance to CAR-T cell therapy, a mutation was detected in exon 3 of CD19 (p.174. L-V). Functional analysis revealed that FMC63 CAR-T cells exhibited antitumor ability against wild-type CD19(+) cells but were unable to eradicate these two types of mutated CD19(+) cells. …”
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  9. 9789
    “…Based on the bioinformatics analysis and the altered exosome proteome profile, we performed biochemical functional analysis to study the diverse properties of these exosomes where angiogenesis, stemness, and anti-oxidative stress properties were validated using different platforms. …”
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  10. 9790
    por Zheng, Wanchun, Xu, Shouming
    Publicado 2020
    “…Compared with the control group, 281 DEPs were significantly up-regulated and 218 were significantly down-regulated after paclitaxel treatment. GO functional analysis, we found that the main functions of these DEPs are binding, catalytic activity, molecular function regulator and so on. …”
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  11. 9791
  12. 9792
    “…Gene ontology (GO) analysis, pathway enrichment analysis, and gene set enrichment analysis (GSEA) were used for functional analysis. STRING and Cytoscape were used to assess the protein-protein interaction (PPI) network and screen hub genes. …”
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  13. 9793
    por Khalil, Ahmad M.
    Publicado 2020
    “…MAIN BODY: Genetic modification techniques cover a wide range of studies, including the generation of transgenic animals, functional analysis of genes, model development for diseases, or drug development. …”
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  14. 9794
    “…CONCLUSION: Our findings suggest that hsa-miR-1246 may act as a biomarker of emphysema in COPD. Functional analysis is guaranteed to elucidate its role in COPD.…”
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  15. 9795
    por Popper, Helmut
    Publicado 2020
    “…The intention of this review is to point to these different aspects and hopefully provoke research directed into a more functional analysis of the metastatic process.…”
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  16. 9796
    “…Of note that SRRM2 and miR-27a-3p were able to distinguish PD patients from healthy individuals. Functional analysis of the similarity between genes associated with SRRM2 and miR-27a/b-3p indicates common functional pathways and their dysfunction correlates with molecular etiopathology mechanisms of PD onset.…”
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  17. 9797
    “…Interestingly, ROR1-AS1 was packaged into exosomes and derived from tumor cells. Functional analysis showed exo-ROR1-AS1 promoted the progression of glioma cell lines SHG44 and U251. …”
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  18. 9798
    “…The expression of 79 genes was up-regulated, while 35 genes were down-regulated. The functional analysis identified a presence of dysregulated interferon signaling pathways (IFI27, IFITM3, RSAD12, GBP7). …”
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  19. 9799
    “…Target genes were also predicted and functional analysis based on Gene Set Enrichment Analysis (GSEA) were then performed. …”
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  20. 9800
    “…For measurement of functional activity of MHC-specific IgE in vitro, a release assay using a rat basophil cell line (RBL-2H3) was established. For functional analysis of MHC-specific IgE in vivo, a cutaneous hypersensitivity reaction assay was adapted for this purpose using MHC monomers. …”
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