“…Moreover, we also found 11 CRs-based model was an independent prognostic factor. Functional analysis suggested that CRs were mainly enriched in cancer-related signaling pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…_HMT_898 in plaques from the BTS group. Functional analysis of the microbial species suggested the existence of a hyperactive metabolic state on teeth surfaces with BTS plaques and revealed that ferric iron, the iron complex transport system, and the iron (III) transport system were more abundant in BTS plaque samples. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we analyzed the clinical impact of Sdc-1 expression by analysis of public gene expression datasets and studied the effect of an overexpression of Sdc-1 and its membrane-bound and soluble forms on the malignant properties of the human cervical carcinoma cell line HeLa through functional analysis. For this purpose, the HeLa cells were stably transfected with the control plasmid pcDNA3.1 and three different Sdc-1-DNA constructs,encoding wild-type, permanently membrane-bound, and constitutively soluble Sdc-1. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We selected 28 genes co-expressed in the hippocampus and PBMCs. A functional analysis of differential genes revealed that they were primarily involved in neuronal death, immune response, and mitochondrial function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This is even more so in the field of genomics, where the advent of next-generation sequencing and the increased ability to perform functional analysis of raw data have had a major effect on the applicability of machine learning in OMICS fields. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The model was then evaluated in three groups (training group, test group and validation group). Functional analysis and immune analysis were used to assess the difference between high-risk and low-risk groups. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, Gene Set Enrichment Analysis (GSEA), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, and Gene Ontology (GO) analysis were performed for biological functional analysis. Finally, the expression level of two m(5)C-related regulators in clinical samples and cell lines was detected by quantitative reverse transcription-polymerase chain reaction and through the Human Protein Atlas database. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Receiver operating characteristic (ROC) curves were used to validate the model in both internal and external cohorts. Functional analysis was generated to evaluate the potential correlation between tumor immunity and ferroptosis-related genes in BRCA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: The results showed that transcriptome profile was globally changed by CELF1 overexpression (CELF1-OE). Functional analysis revealed CELF1 specifically increased the expression of genes in extracellular matrix disassembly, extracellular matrix organization, and proteolysis, which could be classified into matrix metalloproteinases (MMPs) family. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: The described method for cutoff identification may be used to prioritize variables in descriptive omics studies for a focused functional analysis, in situations where other methods of dichotomization of data are inaccessible. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The ESCA hazard model and nomogram map were constructed by integrating the clinical data. We used functional analysis and protein-protein interaction (PPI) networks to explore underlying pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, we found that GGT5 was positively co-expressed with immune-related genes and immune checkpoint genes. Functional analysis revealed that differentially expressed genes relative to GGT5 were mainly involved in the biological processes of immune and inflammatory responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OCTA revealed a significant decrease in vascular flow in the deep capillary layer of the retina. Functional analysis showed that scotopic responses were intact at 2 weeks; however, normal photopic and scotopic responses were hardly detected in mice with EAU mice at 3 weeks postimmunization. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The injured nerve in group C was covered with a collagen membrane soaked with FK506 (0.5 mg/0.1 mL) and fibrin glue. Functional analysis and microscopic evaluation were performed at 2 and 4 weeks after injury. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, the functional analysis revealed that AhSAUR3 played a negative role in response to drought tolerance. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The NET-associated regulatory patterns linked to shorter or longer cancer patient survival were distinct from each other. Functional analysis revealed that more of the NET-associated regulatory genes linked to poor cancer survival were associated with extracellular matrix (ECM) remodeling and pan-cancerous risk factors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A miRNA–mRNA regulatory network including these three key differentially expressed miRNAs and 119 intersecting differentially expressed mRNAs was constructed. Functional analysis of the intersecting differentially expressed mRNAs revealed that an abnormal inflammatory response characterized by disturbed T-helper cell 17 (Th17) differentiation was the primary altered biological function. qRT-PCR validated the decreased expression of Th17 cell differentiation-related genes, including interleukin (IL)17A, IL21, IL22, and IL1β, and the increased expression of retinoic acid receptor-related orphan receptor gamma-t (RORγt) in CSDS mice, which showed significant depressive- and anxiety-like behaviors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Soil microorganisms regulated sorghum growth mainly through 30 pathways, focus including ko00540, ko00471, ko00072 and ko00550, of which ko02030 (Bacterial chemotaxis) and ko00072 (Synthesis and degradation of ketone bodies) played the most critical role. The functional analysis of soil microbial populations revealed that N0Y fertilizer model significantly reduced the intracellular trafficking, secretion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: We proposed a modulatory analysis to infer the ceRNA effects among mRNAs and lncRNAs and performed functional analysis to reveal the plausible mechanisms of lncRNA modulation in the four breast cancer subtypes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, we applied multivariate Cox regression analysis adjusted for clinical characteristics and treatment responses to identify a set of survival-predictive lncRNAs, which were subsequently used for functional analysis of protein-encoding genes to identify downstream biological pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso