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Climatic variables influence annual P. montezumae growth
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10261por Ishiko, Shinya, Morisada, Naoya, Kondo, Atsushi, Nagai, Sadayuki, Aoto, Yuya, Okada, Eri, Rossanti, Rini, Sakakibara, Nana, Nagano, China, Horinouchi, Tomoko, Yamamura, Tomohiko, Ninchoji, Takeshi, Kaito, Hiroshi, Hamada, Riku, Shima, Yuko, Nakanishi, Koichi, Matsuo, Masafumi, Iijima, Kazumoto, Nozu, Kandai“…The minigene assay results indicate the importance of functional analysis, and call into question the fundamental belief that at least one non-truncating mutation is necessary for perinatal survival. …”
Publicado 2021
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10262por Sundaram, Kumaran, Mu, Jingyao, Kumar, Anil, Behera, Jyotirmaya, Lei, Chao, Sriwastva, Mukesh K, Xu, Fangyi, Dryden, Gerald W, Zhang, Lifeng, Chen, ShaoYu, Yan, Jun, Zhang, Xiang, Park, Juw Won, Merchant, Michael L, Tyagi, Neetu, Teng, Yun, Zhang, Huang-Ge“…Memory function of the mice was determined by several memory functional analysis. The effect of GaELNs on glucose and insulin response of the mice was determined by glucose and insulin tolerance tests. c-Myc localization and interaction with BASP1 and calmodulin was determined by confocal microscopy. …”
Publicado 2022
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10263por Zago, Elisa, Dal Molin, Alessandra, Dimitri, Giovanna Maria, Xumerle, Luciano, Pirazzini, Chiara, Bacalini, Maria Giulia, Maturo, Maria Giovanna, Azevedo, Tiago, Spasov, Simeon, Gómez-Garre, Pilar, Periñán, María Teresa, Jesús, Silvia, Baldelli, Luca, Sambati, Luisa, Calandra-Buonaura, Giovanna, Garagnani, Paolo, Provini, Federica, Cortelli, Pietro, Mir, Pablo, Trenkwalder, Claudia, Mollenhauer, Brit, Franceschi, Claudio, Liò, Pietro, Nardini, Christine“…Moreover, interestingly, functional analysis revealed that hsa-miR-144-3p is involved in the regulation of coagulation, a process known to be altered in Parkinson’s Disease. …”
Publicado 2022
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10264por Pramanick, Rinku, Nathani, Neelam, Warke, Himangi, Mayadeo, Niranjan, Aranha, Clara“…Proteobacteria positively correlated to Tenericutes, and Bacteroidetes were shown to be positively correlated to Fusobacteria. Predicted functional analysis indicated differences in the functional profiles between BV and normal microbiota. …”
Publicado 2022
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10265“…CONCLUSION: Our methodology increases the level of integration of genomics data analysis tools to network inference, facilitating hypothesis building, functional analysis and genomics discovery from large scale NGS data. …”
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10266“…The differentially expressed genes (DEGs) in gastric cancer were derived from The Cancer Genome Atlas (TCGA) database, the protein-protein interaction (PPI) network was derived from the Human Protein Reference Database (HPRD), and the Database for Annotation, Visualization and Integrated Discovery (DAVID) facilitated the functional analysis. The cell function was tested by CCK-8 cell viability assay, colony formation assay, acridine orange/ethidium bromide (AO/EB) staining, and Transwell assay. …”
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10267por Zhen, Jianhua, Zhao, Pengfei, Li, Yini, Cai, Yanan, Yu, Wanchen, Wang, Wei, Zhao, Lu, Wang, Hesong, Huang, Guangrui, Xu, Anlong“…Differences in GM, urine metabolites and plasma proteins between allergic and healthy individuals were displayed using principal component analysis (PCoA) and heatmap, and the co-occurrence network was visualized in Cytoscape using Spearman correlation among differential predominant genera, metabolites and proteins. The functional analysis was performed according to the Kyoto Encyclopedia of Genes and Genomes (KEGG) dataset. …”
Publicado 2022
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10268“…The comprehensive investigation reported in this study will be an important basis for studying the molecular evolution of the vertebrate C6astacin genes, hatching enzyme, and its paralogous genes and for identifying these genes without the need for gene expression and functional analysis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12862-022-01966-2.…”
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10269por Wang, Guanglin, Wang, Feifei, Meng, Zesong, Wang, Na, Zhou, Chaoxi, Zhang, Juan, Zhao, Lianmei, Wang, Guiying, Shan, Baoen“…METHODS: Firstly, the data of gene transcriptome and genome-wide DNA methylation expression were downloaded from the Gene Expression Omnibus database. Secondly, functional analysis of differentially expressed and differentially methylated genes was performed, followed by protein-protein interaction (PPI) analysis. …”
Publicado 2022
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10270“…The assembly serves as a reference for read mapping, and the annotation is necessary for functional analysis of genes found to be differentially expressed. …”
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10271por Su, Linfan, Qiao, Yixian, Luo, Jinmei, Huang, Rong, Li, Zhiwei, Zhang, Hongbing, Zhao, Hongmei, Wang, Jing, Xiao, Yi“…Furthermore, discriminative bacteria, such as Haemophilus, were identified as being specific taxa in AECOPD patients. Functional analysis showed that genes involved in membrane transport and signal transduction metabolism were enriched in the AECOPD group. …”
Publicado 2022
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10272por Soma, Emi, Yamayoshi, Asako, Toda, Yuki, Mishima, Yuji, Hosogi, Shigekuni, Ashihara, Eishi“…We also conducted a functional analysis of anti-CD63 mAb-conjugated siRNAs. …”
Publicado 2022
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10273por Ding, Hongmei, Jiang, Fei, Deng, Lifeng, Wang, Juan, Wang, Ping, Ji, Mintao, Li, Jie, Shi, Weiqiang, Pei, Yufang, Li, Jiafu, Zhang, Yue, Zhang, Zengli, Chen, Youguo, Li, Bingyan“…Intriguingly, the p-value of combined 3-lncRNAs was lower than that of each lncRNA, indicating that the 3-lncRNA signature also showed higher performance in EC tissue than paracancerous. Functional analysis revealed that cortactin might be involved in the mechanism of 3-lncRNA signatures. …”
Publicado 2022
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10274por Wang, Jiao, Cai, Wei, Yu, Jiao, Liu, Honghong, He, Shasha, Zhu, Lingyan, Xu, Jixiong“…Associations between CAGs and clinical parameters were analyzed using Spearman correlation; predictive functional analysis of gut microbiota was performed using Kyoto Encyclopedia of Genes and Genomes data. …”
Publicado 2022
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10275por Kalinichenko, Liubov S., Mühle, Christiane, Jia, Tianye, Anderheiden, Felix, Datz, Maria, Eberle, Anna-Lisa, Eulenburg, Volker, Granzow, Jonas, Hofer, Martin, Hohenschild, Julia, Huber, Sabine E., Kämpf, Stefanie, Kogias, Georgios, Lacatusu, Laura, Lugmair, Charlotte, Taku, Stephen Mbu, Meixner, Doris, Tesch, Nina, Praetner, Marc, Rhein, Cosima, Sauer, Christina, Scholz, Jessica, Ulrich, Franziska, Valenta, Florian, Weigand, Esther, Werner, Markus, Tay, Nicole, Mc Veigh, Conor J., Haase, Jana, Wang, An-Li, Abdel-Hafiz, Laila, Huston, Joseph P., Smaga, Irena, Frankowska, Malgorzata, Filip, Malgorzata, Lourdusamy, Anbarasu, Kirchner, Philipp, Ekici, Arif B., Marx, Lena M., Suresh, Neeraja Puliparambil, Frischknecht, Renato, Fejtova, Anna, Saied, Essa M., Arenz, Christoph, Bozec, Aline, Wank, Isabel, Kreitz, Silke, Hess, Andreas, Bäuerle, Tobias, Ledesma, Maria Dolores, Mitroi, Daniel N., Miranda, André M., Oliveira, Tiago G., Gulbins, Erich, Lenz, Bernd, Schumann, Gunter, Kornhuber, Johannes, Müller, Christian P.“…A genetic association analysis in 456,693 volunteers found associations of haplotypes of SMPD3 coding for NSM-2 (NSM) with alcohol consumption, but also with affective state, and bone mineralisation. Functional analysis in mice showed that NSM controls alcohol consumption, affective behaviour, and their interaction by regulating hippocampal volume, cortical connectivity, and monoaminergic responses. …”
Publicado 2021
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10276por Kan, Shuang, Li, Rong, Tan, Yanhui, Yang, Fang, Xu, Shaohua, Wang, Lingzhu, Zhang, Lijun, Sun, Xuchen, Chen, Xuanming, Yang, Yuting, Shu, Wei, Wan, Huaibin, Chen, Zheng-Feng, Liang, Hong, Chen, Ming“…In vitro studies indicated that LXN was highly induced during adipocyte differentiation, and positively regulated adipocyte differentiation and adipogenesis in 3T3-L1 cells and primary preadipocytes. Functional analysis revealed that the expression of LXN was positively regulated by mTOR/RXR/PPARɤ signaling pathway during the differentiation of adipocytes, while LXN deletion decreased the protein level of PPARɤ in adipocyte through enhancing FABP4 mediated ubiquitination, which led to impaired adipocyte differentiation and lipogenesis. …”
Publicado 2022
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10277por Jiang, Aiming, Zou, Chengwu, Xu, Xiang, Ke, Zunwei, Hou, Jiangan, Jiang, Guihe, Fan, Chunli, Gong, Jianhua, Wei, Jiguang“…The phylogenetic tree indicated that HJ-2 is most closely related to P. peoriae IBSD35. Functional analysis of genome revealed numerous genes/gene clusters involved in plant colonization, biofilm formation, plant growth promotion, antibiotic and resistance inducers synthesis. …”
Publicado 2022
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10278por Shen, Chen-Hui, Peng, Li-Juan, Zhang, Yu-Xing, Zeng, Hua-Rui, Yu, Hong-Fei, Jin, Lin, Li, Guo-Qing“…Our findings will be beneficial for improving the accuracy of qRT-PCR analysis for future functional analysis of the target gene expression in P. operculella. …”
Publicado 2022
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10279por Cheng, Xinran, Gao, Chang, Liu, Xue, Xu, Dongmei, Pan, Xu, Gao, Wei, Yan, Shengnan, Yao, Hui, Cao, Jiajia, Min, Xiaoyu, Lu, Jie, Chang, Cheng, Zhang, Haiping, Ma, Chuanxi“…These findings provide useful information for further cloning and functional analysis of TaVQ genes and introduce useful candidate genes for the improvement of PHS resistance in wheat. …”
Publicado 2022
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10280por dos Santos, Guilherme Brzoskowski, da Silva, Edileuza Danieli, Kitano, Eduardo Shigueo, Battistella, Maria Eduarda, Monteiro, Karina Mariante, de Lima, Jeferson Camargo, Ferreira, Henrique Bunselmeyer, Serrano, Solange Maria de Toledo, Zaha, Arnaldo“…We identified 280 parasitic proteins from E. granulosus and 251 from E. ortleppi, including 52 parasitic proteins that were common to all hydatid fluid samples. The in silico functional analysis revealed important molecular functions and processes that are active in pulmonary cystic echinococcosis, such as adhesion, extracellular structures organization, development regulation, signaling transduction, and enzyme activity. …”
Publicado 2022
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